ChemicalBook > CAS DataBase List > 4-Nitrophenylacetic acid

4-Nitrophenylacetic acid

Product Name
4-Nitrophenylacetic acid
CAS No.
104-03-0
Chemical Name
4-Nitrophenylacetic acid
Synonyms
2-(4-NITROPHENYL)ACETIC ACID;4-NITRO-A-TOLUIC ACID;4-NITROBENZENEACETIC ACID;paraNitro Phenyl Acetic Acid;4-Nitrophenylacetic;RARECHEM AL BO 0237;4-Nitrobenzencacetic;-Nitro-a-toluic acid;p-Nitro-α-toluicacid;Nitrophenylacetic aci
CBNumber
CB1671726
Molecular Formula
C8H7NO4
Formula Weight
181.15
MOL File
104-03-0.mol
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4-Nitrophenylacetic acid Property

Melting point:
150-155 °C(lit.)
Boiling point:
314.24°C (rough estimate)
Density 
1.4283 (rough estimate)
refractive index 
1.5468 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
3.85(at 25℃)
form 
Crystalline Powder
color 
Beige to yellow
PH
2.98 at 22.8℃ and 10g/L
Water Solubility 
slightly soluble
Merck 
14,6621
BRN 
1911801
InChIKey
YBADLXQNJCMBKR-UHFFFAOYSA-N
LogP
0.3 at 30℃ and pH7.72
CAS DataBase Reference
104-03-0(CAS DataBase Reference)
EPA Substance Registry System
4-Nitrophenylacetic acid (104-03-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
AJ1130010
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29163900
Toxicity
dnr-bcs 500 mg/disc MUREAV170,11,86
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N20204
Product name
4-Nitrophenylacetic acid
Purity
ReagentPlus , 99%
Packaging
25g
Price
$54.1
Updated
2024/03/01
Sigma-Aldrich
Product number
N20204
Product name
4-Nitrophenylacetic acid
Purity
ReagentPlus , 99%
Packaging
100g
Price
$95.7
Updated
2024/03/01
TCI Chemical
Product number
N0227
Product name
4-Nitrophenylacetic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
N0227
Product name
4-Nitrophenylacetic Acid
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$254
Updated
2024/03/01
Alfa Aesar
Product number
A15901
Product name
4-Nitrophenylacetic acid, 98%
Packaging
25g
Price
$29.65
Updated
2024/03/01
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4-Nitrophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder
4-Nitrophenylacetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the para- position by a nitro group.

Uses

(4-Nitrophenyl)acetic Acid used in the synthesis of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones which may act as angiogenesis inhibitors. Also used in the one step construction of amino-substituted squaraine dye.

Uses

Intermediate for dyestuffs, pharmaceuticals, penicillin precursors, local anesthetics.

Definition

ChEBI: A monocarboxylic acid that is phenylacetic acid carrying a nitro substituent at position 4.

Safety Profile

Moderately toxic intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

Crystallise the acid from EtOH/water (1:1), then from sodium-dried diethyl ether and dry it over P2O5 in vacuo. The styphnate has m 196.5-197o (prisms from EtOH). The amide has m 191o (from EtOH). [Beilstein 9 III 2284, 9 IV 1698.]

4-Nitrophenylacetic acid Preparation Products And Raw materials

Raw materials

p-Nitrophenylacetonitrile

Preparation Products

4-Aminophenylacetic acid
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4-Nitrophenylacetic acid Suppliers

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View Lastest Price from 4-Nitrophenylacetic acid manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Nitrophenylacetic acid 104-03-0
Price
US $12.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-23
Hebei Weibang Biotechnology Co., Ltd
Product
(4-nitrophenyl)acetic acid 104-03-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-02-08
Henan Fengda Chemical Co., Ltd
Product
4-Nitrophenylacetic acid 104-03-0
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24

104-03-0, 4-Nitrophenylacetic acidRelated Search:

(4-Nitrophenyl)methyl 3-oxobutanoate 4-Nitrobenzaldehyde Ethyl 2-(Chlorosulfonyl)acetate 4-NITROPHENYLACETIC ACID ETHYL ESTER,P-NITROPHENYLACETIC ACID ETHYL ESTER 4-NITROPHENYL ACETATE 4-Nitrobenzyl alcohol 4-Nitroacetophenone Sodium 3-nitrobenzenesulphonate 4-Nitrobenzoic acid ALPHA-ETHYL-4-NITROPHENYLACETIC ACID 4-NITROPHENYLACETYLENE Methyl 4-bromobenzoate 4-Nitrophenyl chloroformate 4-Bromophenylacetic acid 4-Hydroxybenzoic acid 3-(4-Hydroxyphenyl)propionic acid 4-Bromomethylbenzoic acid 4'-Hydroxyacetophenone

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