DEXBROMPHENIRAMINE MALEATE

Product Name: DEXBROMPHENIRAMINE MALEATE
CAS No.: 2391-03-9
Chemical Name: DEXBROMPHENIRAMINE MALEATE
Synonyms: D03704;Disophrol;Disomer (tn);disomermaleate;DexbroMpheniraMin;Brompheniramine d-;Dexbrompheniraminum;d-brompheniraminemaleate;DEXBROMPHENIRAMINE MALEATE;(S)-BroMpheniraMine Maleate
CBNumber: CB1675360
Molecular Formula: C20H23BrN2O4
Formula Weight: 435.31
MOL File: 2391-03-9.mol

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DEXBROMPHENIRAMINE MALEATE Property

Melting point:: 132-134℃
storage temp.: -20°C Freezer
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 22-36/37/39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: US4026200
HS Code: 2933399090
Toxicity: guinea pig,LD50,oral,259mg/kg (259mg/kg),SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYEBEHAVIORAL: TREMORBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Chemotherapia. Vol. 3, Pg. 120, 1961.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB19340
Product name: (S)-Brompheniramine maleate
Packaging: 10mg
Price: $40
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19340
Product name: (S)-Brompheniramine maleate
Packaging: 25mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19340
Product name: (S)-Brompheniramine maleate
Packaging: 50mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19340
Product name: (S)-Brompheniramine maleate
Packaging: 100mg
Price: $190
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19340
Product name: (S)-Brompheniramine maleate
Packaging: 250mg
Price: $300
Updated: 2021/12/16

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DEXBROMPHENIRAMINE MALEATE Chemical Properties,Usage,Production

Originator

Disomer,White,US,1959

Uses

The S-enantimer of Brompheniramine maleate (B686355) as antihistaminic.

Definition

ChEBI: The maleic acid salt of the (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used for the symptomatic relief of allergic conditions, including rhinitis and co junctivitis.

Manufacturing Process

The following is taken from US Patent 3,061,517. Sixteen grams of racemic 3- (2-pyridyl)-3-p-bromophenyl-N,N,-dimethylpropylamine and 9.7 grams of dphenylsuccinic acid are dissolved in 150 ml of absolute alcohol and kept at room temperature until crystallization is effected. The crystals are filtered,washed with absolute ethyl alcohol, and recrystallized from the same solvent using 5 ml there of per gram of solid. Three subsequent crystallizations from 80% alcohol give d-3-(2-pyridyl)-3-p-bromophenyl-N,N-dimethylpropylamined-phenylsuccinate; MP 152-154°C; [α]D25 91 (concentration, 1% in dimethylformamide).
The free base, d-3-(2-pyridyl)-3-p-bromophenyl-N,N-dimethylpropylamine, is obtained from this salt with diethyl ether and aqueous potassium carbonate; [α]D25 +42.7 (concentration, 1% in dimethylformamide). The free base is then reacted with maleic acid.

brand name

Disomer (Schering).

Therapeutic Function

Antihistaminic

General Description

Like the chlorinederivative, the antihistaminic activity of brompheniramineexists predominantly in the dextro isomer, dexbrompheniraminemaleate (D-isomer), and is of comparable potency.

DEXBROMPHENIRAMINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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DEXBROMPHENIRAMINE MALEATE Suppliers

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2391-03-9, DEXBROMPHENIRAMINE MALEATERelated Search:

Maleic acid DEXBROMPHENIRAMINE MALEATE 4-Bromocumene DEXBROMPHENIRAMINE 3-(2-PYRIDINYL)PROPYLAMINE Brompheniramine Ammonium hydrogen maleate Pheniramine maleate

(+)-2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate

d-brompheniraminemaleate

disomermaleate

gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(s)-2-pyridinepropanamin(z)-2-buten

pyridine,2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-,maleate(1:1),(s)

(+)-BROMPHENIRAMINE MALEATE SALT

DEXBROMPHENIRAMINE MALEATE

DEXBROMPHENIRAMINE MALEATE SALT

(S)-2-[p-bromo-alpha-[2-(dimethylamino)ethyl]benzyl]pyridinium (Z)-maleate (1:1)

D03704

Dexbrompheniramine maleate (usan)

Disomer (tn)

Dexbrompheniramine Maleate (200 mg)

(S)-BroMpheniraMine Maleate

(S)-2-[p-BroMo-α-[2-(diMethylaMino)ethyl]benzyl]pyridine Maleate

(γS)-γ-(4-broMophenyl)-N,N-diMethyl-2-pyridinepropanaMine (2Z)-2-Butenedioate

1-(p-BroMophenyl)-1-(2-pyridyl)-3-diMethylaMine Propane Maleate

DexbroMpheniraMin

Dexbrompheniramine maleateQ: What is Dexbrompheniramine maleate Q: What is the CAS Number of Dexbrompheniramine maleate Q: What is the storage condition of Dexbrompheniramine maleate Q: What are the applications of Dexbrompheniramine maleate

Dexbrompheniramine Maleate (1178002)

Brompheniramine d-

Dexbrompheniraminum

Disophrol

2391-03-9

Br1C16H19N2

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Aromatics

Heterocycles

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