1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride

Product Name: 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride
CAS No.: 90604-02-7
Chemical Name: 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride
Synonyms: 1-BENZHYDRYLAZETIDIN-3-OL HYDROCHLORIDE;1-(DiphenylMethyl)-3-hydroxyazetidine HCl;1-(diphenylmethyl)azetidin-3-ol hydrochloride;Baricitinib-008-HCl;Baricitinib Impurity 9 HCl;1-BENZHYDRYLAZETAN-3-OL-HCl;Baricitinib Impurity 13 HCl;N-BENZHYDRYLAZETIDIN-3-OL HCL;1-BENZHYDRYL AZETIDIN-3-OL HCL;1-benzhydrylazetidin-1-ium-3-ol
CBNumber: CB1683228
Molecular Formula: C16H18ClNO
Formula Weight: 275.78
MOL File: 90604-02-7.mol

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1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Property

Melting point:: 172-174°C
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
form: Solid
color: White to Pale Yellow
CAS DataBase Reference: 90604-02-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37
Hazard Note: Irritant
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D492848
Product name: 1-(Diphenylmethyl)-3-hydroxyazetidineHydrochloride
Packaging: 2.5g
Price: $45
Updated: 2021/12/16

TRC

Product number: D492848
Product name: 1-(Diphenylmethyl)-3-hydroxyazetidineHydrochloride
Packaging: 5g
Price: $60
Updated: 2021/12/16

Synthonix

Product number: B10215
Product name: 1-Benzhydrylazetidin-3-olhydrochloride
Purity: 97.0%
Packaging: 500g
Price: $60
Updated: 2021/12/16

Ark Pharm

Product number: AK-27694
Product name: 1-Benzhydrylazetidin-3-olhydrochloride
Purity: 97%
Packaging: 10g
Price: $7
Updated: 2021/12/16

Matrix Scientific

Product number: 112093
Product name: 3-Azetidinol
Purity: 1-(diphenylmethyl)-hydrochloride (1:1)
Packaging: 1g
Price: $11
Updated: 2021/12/16

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1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Chemical Properties,Usage,Production

Uses

1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride is a vital compound and can be used to synthesise 1-Benzhydrylazetidin-3-one and 1-benzhydrylazetidin-3-ol.

Synthesis

18621-17-5

90604-02-7

General procedure for the synthesis of 1-(diphenylmethyl)-3-hydroxyazetidine hydrochloride from 1-diphenylmethyl-3-hydroxyazetidine: 1-(diphenylmethyl)-3-hydroxyazetidine (9.70 g) was suspended in a 4.5 M hydrochloric acid solution of ethyl acetate (35 mL) at room temperature and the reaction was stirred for 10 minutes. Subsequently, the solvent was removed by evaporation to give 1-(diphenylmethyl)-3-hydroxyazetidine hydrochloride (12.0 g, 100% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6, with TMS as internal standard) with the following chemical shifts (ppm): δ 7.30-7.70 (10H, m, arylhydrogen), 5.85 (1H, s, CH), 5.80 (1H, d, OH), 4.46 (1H, m, CH), 3.70-4.20 (4H, m, CH2 ).

References

[1] Patent: WO2007/118830, 2007, A1. Location in patent: Page/Page column 91

1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Suppliers

China 194 France 1 Germany 1 India 5 Japan 1 United Kingdom 7 United States 21 Global 230

J & K SCIENTIFIC LTD.

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View Lastest Price from 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride 90604-02-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-28

Henan Aochuang Chemical Co.,Ltd.

Product: 1-(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE 90604-02-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

Career Henan Chemical Co

Product: 1-(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE 90604-02-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-03-05

90604-02-7, 1-(Diphenylmethyl)-3-Hydroxyazetidine HydrochlorideRelated Search:

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90604-02-7

C16H18NOCl

C16H17NOHCl

C16H17NOClH