DEHYDROABIETYLAMINE

Product Name: DEHYDROABIETYLAMINE
CAS No.: 1446-61-3
Chemical Name: DEHYDROABIETYLAMINE
Synonyms: Leelamine;AMINE D;DEHYDROABIETHYLAMINE;((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine;NSC 2955;55.0%(GC);Leelamine HCl;((1R,4aS,10aR);Water galbanum;Dehydrobietylamine
CBNumber: CB1692875
Molecular Formula: C20H31N
Formula Weight: 285.47
MOL File: 1446-61-3.mol

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DEHYDROABIETYLAMINE Property

Melting point:: 44.50℃
Boiling point:: 417.89°C (rough estimate)
Density: 0.963±0.06 g/cm3 (20 ºC 760 Torr)
refractive index: n20/D 1.546(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform, DMSO, Methanol
form: White solid.
pka: 10.13±0.29(Predicted)
color: Pale Yellow
optical activity: [α]20/D +56.1°, c = 2.4 in pyridine
BRN: 3084620
CAS DataBase Reference: 1446-61-3(CAS DataBase Reference)
EPA Substance Registry System: Dehydroabietylamine (1446-61-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: TP8701000
F: 10-23
HS Code: 29214990
Hazardous Substances Data: 1446-61-3(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 105198
Product name: (+)-Dehydroabietylamine
Purity: technical grade, 60%
Packaging: 100g
Price: $48.4
Updated: 2024/03/01

TCI Chemical

Product number: D1588
Product name: (+)-Dehydroabietylamine [Optical Resolving Agent]
Purity: >90.0%(GC)
Packaging: 5g
Price: $94
Updated: 2024/03/01

TCI Chemical

Product number: D1180
Product name: Dehydroabietylamine
Purity: min. 55.0 %
Packaging: 25G
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: D1588
Product name: (+)-Dehydroabietylamine [Optical Resolving Agent]
Purity: >90.0%(GC)
Packaging: 25g
Price: $282
Updated: 2024/03/01

Cayman Chemical

Product number: 10006148
Product name: Leelamine
Purity: ≥98%
Packaging: 5mg
Price: $37
Updated: 2024/03/01

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DEHYDROABIETYLAMINE Chemical Properties,Usage,Production

Chemical Properties

clear yellow viscous liquid

Uses

Dehydroabiethylamine is a primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans.

Definition

ChEBI: [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine is a diterpenoid.

Biological Activity

CB 1 agonist. Displaces binding of [ 3 H]-SR141716A with an IC 50 value of 2.86 μ M.

Purification Methods

The crude base is purified by converting 2g of base in toluene (3.3mL) into the acetate salt by heating at 65-70o with 0.46g of AcOH, and the crystals are collected and dried (0.96g from two crops, m 141-143o). The acetate salt is dissolved in warm H2O, basified with aqueous NaOH and extracted with *C6H6. The dried extract (MgSO4) is evaporated in vacuum leaving a viscous oil which crystallises and can be distilled. [Gottstein & Cheney J Org Chem 30 2072 1965.] The picrate has m 234-236o (from aqueous MeOH), and the formate has m 147-148o (from heptane). [Beilstein 12 IV 3005.]

DEHYDROABIETYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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DEHYDROABIETYLAMINE Suppliers

Americas 1 Belgium 1 Canada 3 China 168 Europe 4 France 2 Germany 4 India 4 Japan 4 Singapore 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 United Kingdom 6 United States 31 Global 235

Carbosynth

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Fisher Scientific Uk Ltd.

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Bio-Techne Ltd. (Tocris Bioscience)

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CMS Chemicals Limited

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Country: United Kingdom
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Tocris Bioscience

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Fluorochem Ltd.

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ProdList: 6401
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View Lastest Price from DEHYDROABIETYLAMINE manufacturers

Jiangsu Monade Biological Technology Co., Ltd.

Product: (+)-Dehydroabiethylamine 1446-61-3
Price: US $0.00/ASSAYS
Min. Order: 100ASSAYS
Purity: 99.99%
Supply Ability: 10000
Release date: 2021-09-07

Career Henan Chemical Co

Product: DEHYDROABIETYLAMINE 1446-61-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

Career Henan Chemical Co

Product: DEHYDROABIETYLAMINE 1446-61-3
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-24

1446-61-3, DEHYDROABIETYLAMINERelated Search:

FMOC-ASN(TRT)-OPFP D-DESTHIOBIOTIN 1951424-89-7 DEHYDROABIETYLAMINE (+)-DEHYDROABIETYLAMINE [OPTICAL RESOLVING AGENT],(+)-DEHYDROABIETYLAMINE [OPTICAL RESOLVING AGENT] Polyethylene oxide, dehydroabietylamine polymer DEHYDROABIETYLAMINE Turpentine DEHYDROABIETYL ISOTHIOCYANATE [1R-(1alpha,4abeta,10aalpha)]-4-[[[7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethylphenanthren-1-yl]methyl](3-oxo-3-phenylpropyl)amino]butan-2-one DEHYDROABIETYLAMINE ACETATE, TECH., 85%,DEHYDROABIETYLAMINE ACETATE,DEHYDROABIETYLAMINE ACETATE, TECH., 85%,DEHYDROABIETYLAMINE ACETATE (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine hydrochloride TOSLAB 13004 TOSLAB 12994 [(1R,4AS,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENYL]-N-(4-FLUOROBENZYL)METHANAMINE HYDROCHLORIDE N-{[(1R,4AS,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENYL]METHYL}-2-PROPANAMINE HYDROCHLORIDE [(1R,4AS,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENYL]-N-(2-METHOXYBENZYL)METHANAMINE HYDROCHLORIDE TOSLAB 13005

(+)-DEHYDROABIETYLAMINE

DEHYDROABIETYLAMINE

(+)-DEHYDROABIETHYLAMINE

DEHYDROABIETHYLAMINE

D(+)-DEHYDROABIETYLAMINE

1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-

1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl-1-phenanthrenemethanamine)

NSC 2955

1-phenanthrenemethanamine,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-met

Dehydrobietylamine

(1R)-(1,2,3,4,4a,9,10,10aα-Octahydro-7-isopropyl-1,4aβ-dimethylphenanthrene)-1α-methanamine

(1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)-1α-phenanthrenemethanamine

(1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)phenanthrene-1α-methanamine

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenemethanamine

Dehydroabietylamine,60%,tech.

Dehydroabietylamine1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1- phenanthrenemethylamine

(d)-dehyroabiethylamine

Leelamine hydrochloride

DEHYDROABIETYLAMINE, TECH., 60%

DehydroabietylamineTech60%

LYLAMINE HYDROCHLORIDE

(1R,4AS,10AR)-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-,4A-DIMETHYL-7-(1-METHYLETHYL)-1-PHENANTHRENEMETHANAMINE HYDROCHLORIDE

1,4A-DIMETHYL-7-ISOPROPYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENEMETHYLAMINE

1 4A-DIMETHYL-7-ISOPROPYL-1 2 3,4A 9 10 10A-OCTAHYDRO-1-PHENANTHRENE METHYLAMINE

AMINE D

(1r-(1alpha,4abeta,10aalpha))-hylethyl)

[1theta-(1alpha,4abeta,10aalpha)]-hylethyl)

1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,[1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine

13-isopropylpodocarpa-8,11,13-trien-15-amine

13-trien-15-amine,13-isopropyl-podocarpa-11

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine ,60%

((1S,4aS,10aR)-7-isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine

Leelamine

(+)DehyroabietylaMine

(1R,4aS,10aR)-1-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-phenanthrenemethanamine

((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine

DehydroabiethylaMine (>80%)

(+)-Dehydroabietylamine technical grade, 60%

Leelamine HCl

(+)-Dehydroabietylamine&nbsp

[Optical Resolving Agent]

((1R,4aS,10aR)

-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4adimethyl- 7-(1-methylethyl)-1-phenanthrenemethanamine,99%d.e.

(+)-Dehydroabietylamine[OpticalResolvingAgent]&gt

55.0%(GC)

Dehydroabietylamine &gt

(+)-Dehydroabietylamine [Optical Resolving Agent]

(+)-Dehydroabiethylamine

1446-61-3 C20H31N DEHYDROABIETYLAMINE

(+)-Dehydroabietylamine

Leelamine free base

Pyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Cannabinoid Receptor,inhibit

Water galbanum

1446-61-3

C20H31N

C20H31NHCl