ChemicalBook > CAS DataBase List > 4-Nitrobenzyl hydrogen malonate

4-Nitrobenzyl hydrogen malonate

Product Name
4-Nitrobenzyl hydrogen malonate
CAS No.
77359-11-6
Chemical Name
4-Nitrobenzyl hydrogen malonate
Synonyms
4-NITROBENZYLMALONATE;P-NITROBENZYLMALONATE;Mononitrobenzyl malonate;2-(4-Nitrobenzyl)malonate;MONO-4-NITROBENZYL MALONATE;MONO P-NITRO BENZYL MALONATE;4-Nitrobenzyl hydrogen malote;Mono-4-nitrobenzylMalonate>Mono-4-nitrobenzylmalonicacides;4-nitrobenzyl hydrogen malonate
CBNumber
CB1714632
Molecular Formula
C10H9NO6
Formula Weight
239.18
MOL File
77359-11-6.mol
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4-Nitrobenzyl hydrogen malonate Property

Melting point:
109 °C
Boiling point:
455.8±30.0 °C(Predicted)
Density 
1.447±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.49±0.32(Predicted)
color 
White to Almost white
InChIKey
RIGFMUNSTCPGNP-UHFFFAOYSA-N
CAS DataBase Reference
77359-11-6(CAS DataBase Reference)
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Safety

HS Code 
2917399590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1177
Product name
Mono-4-nitrobenzyl Malonate
Purity
>98.0%(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
M1177
Product name
Mono-4-nitrobenzyl Malonate
Purity
>98.0%(T)
Packaging
25g
Price
$276
Updated
2024/03/01
TRC
Product number
N495570
Product name
3-[(4-Nitrobenzyl)oxy]-3-oxopropanoicAcid
Packaging
1g
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
075703
Product name
3-((4-Nitrobenzyl)oxy)-3-oxopropanoic acid
Purity
95+%
Packaging
100g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
075703
Product name
3-((4-Nitrobenzyl)oxy)-3-oxopropanoic acid
Purity
95+%
Packaging
5g
Price
$13
Updated
2021/12/16
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4-Nitrobenzyl hydrogen malonate Chemical Properties,Usage,Production

Uses

4-Nitrobenzyl hydrogen malonate is a reagent used in the synthesis of (±)-thienamycin, a β-Lactam antibiotics. Also, it is useful for chiral key intermediate of carbapenem syntheses.

Preparation

Preparation of mono-4-nitrobenzyl malonate:
In a flame-dried 150 mL pressure tube under argon, add 5.00 g (34.7 mmol) of Meldrum's acid and 40 mL of anhydrous MeCN.
Add 5.58 g (36.4 mmol) of p-nitrobenzyl alcohol to the resulting solution.
Cap the tube tightly and reflux the reaction overnight.
Concentrate the reaction mixture under reduced pressure.
Purify the residue using column chromatography with a 55/45 hexane/EtOAc mixture.
The resulting product is mono-4-nitrobenzyl malonate with a yield of 87%.

4-Nitrobenzyl hydrogen malonate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Nitrobenzyl hydrogen malonate manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Nitrobenzyl hydrogen malonate 77359-11-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99.00%
Supply Ability
20tons
Release date
2023-09-15
Hebei Mojin Biotechnology Co., Ltd
Product
4-Nitrobenzyl hydrogen malonate 77359-11-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-23
Xinxiang Hongqi District Houyuan Trading Co.,Ltd
Product
Mono-4-nitrobenzylmalonicacidester 77359-11-6
Price
US $0.00/Kg
Min. Order
1Kg
Purity
99.0% up
Supply Ability
50 tons per month
Release date
2023-05-31

77359-11-6, 4-Nitrobenzyl hydrogen malonateRelated Search:

Diethyl methylmalonate Ethyl hydrogen malonate (4-Nitrophenyl)methyl 3-oxobutanoate 4-Nitrobenzyl chloroformate Dimethyl malonate Hydrogen Malonic acid 4-Nitrobenzyl alcohol Diethyl malonate 4-(Benzyloxycarbonyl)-2-azetidinone 2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID Propanoic acid, 2,2-diMethyl-3-oxo-, Methyl ester Malonyl chloride Methyl malonyl chloride BPMO MALONIC ACID MONO-4-NITROBENZYL ESTER MAGNESIUM SALT 4-Nitrobenzyl chloride Hydrogen peroxide

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