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N-acetyl aspartyl-glutaMic acid

Product Name
N-acetyl aspartyl-glutaMic acid
CAS No.
3106-85-2
Chemical Name
N-acetyl aspartyl-glutaMic acid
Synonyms
NAAG;NAAGA;Naaxia;α-NAAG;ZY-15106;AC-ASP-GLU;ALPHA-NAAG;ACETYL-D-E;AC-ASP-GLU-OH;AC-ASP-GLU H2O
CBNumber
CB1742046
Molecular Formula
C11H16N2O8
Formula Weight
304.25
MOL File
3106-85-2.mol
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N-acetyl aspartyl-glutaMic acid Property

Melting point:
171-173 °C
Boiling point:
769.5±60.0 °C(Predicted)
Density 
1.472±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
powder
pka
3.04±0.10(Predicted)
color 
white
optical activity
[α]22/D 34.5°, c = 1.1 in H2O(lit.)
Water Solubility 
Soluble to 100 mM in water
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A5930
Product name
N-Acetyl-Asp-Glu
Purity
≥97% (TLC), powder
Packaging
25mg
Price
$137
Updated
2024/03/01
Sigma-Aldrich
Product number
A5930
Product name
N-Acetyl-Asp-Glu
Purity
≥97% (TLC), powder
Packaging
100mg
Price
$384
Updated
2024/03/01
Usbiological
Product number
166584
Product name
Spaglumic Acid
Packaging
50mg
Price
$403
Updated
2021/12/16
TRC
Product number
S679100
Product name
SpaglumicAcid
Packaging
50mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA05316
Product name
N-Acetyl-L-aspartyl-L-glutamic acid
Packaging
100mg
Price
$65
Updated
2021/12/16
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N-acetyl aspartyl-glutaMic acid Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Acetyl-Asp-Glu has been used in N-acetylated α-linked acidic dipeptidase (NAALADase) assay and affinity experiments.

Uses

N-acetyl aspartyl-glutamic acid is a spaglumic acid is a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments.

Definition

ChEBI: A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage.

General Description

NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system. It remains uncertain whether this compound activates NMDA receptors; however, it is clearly demonstrated to act as a selective agonist of mGluR3, both in vitro and in vivo.

Biochem/physiol Actions

Endogenous neurotransmitter localized to neurons with high affinity for metabotropic glutamate receptors, mGluR3. It is an antagonist at NMDA receptors. Catabolized by carboxypeptidase II, which is expressed on astrocyte membranes, to N-acetylaspartate and glutamate.

storage

-20°C

N-acetyl aspartyl-glutaMic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-acetyl aspartyl-glutaMic acid Suppliers

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View Lastest Price from N-acetyl aspartyl-glutaMic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-acetyl aspartyl-glutaMic acid 3106-85-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-11

3106-85-2, N-acetyl aspartyl-glutaMic acidRelated Search:

Isobutyramide Caspase 8 Fluorometric Substrate, IETD-AFC (FLICE, MASH, Mch5, N-acetyl-Asp-Glu-Val-Asp-AFC ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE,N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE),N-ACETYL-ASP-GLU-VAL-ASP-AL N-acetyl aspartyl-glutaMic acid N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE PNA,N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE,ACETYL-ASP-GLU-VAL-ASP-(P-NITROANILIDE) MGVRNSVLSGKKADE H-VAL-GLY-ASP-GLU-OH AC-DEVD-AMC AC-DEVD-AFC ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE,N-ACETYL-ASP-GLU-VAL-ASP-AL,N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE),N-acetyl-Asp-Glu-Val-Asp-Ala MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH N-ACETYL-ASP-GLU-HIS-ASP-7-AMIDO-4-METHYLCOUMARIN TRIFLUOROACETATE SALT Caspase 8 Colorimetric Substrate (FLICE, MASH, Mch5, N-acetyl-Asp-Glu-Val-Asp-pNA (p-nitroanilide)) Caspase 8 Fluorometric Substrate, IETD-AFC N-acetyl-Asp-Glu-Val-Asp-AFC, 7-amino-4-trifluoromethyl coumarin) (FLICE, MASH, Mch5, Caspase 8 Colorimetric Substrate, N-acetyl-Asp-Glu-Val-Asp-pNA p-nitroanilide (FLICE, MASH, Mch5) N-ACETYL-ASP-GLU-HIS-ASP-7-AMINO-4-METHY PROTEIN PHOSPHATASE 2A/A (7-19) BLOCKING PEPTIDE NAAG, [GLUTAMATE-3,4-3H]-

  • SPAGLUMIC ACID
  • NAAG
  • N-ACETYL-L-ASPARTYL-L-GLUTAMIC ACID
  • N-ACETYLASPARTYLGLUTAMIC ACID
  • N-ACETYL-ASP-GLU
  • N-ACETYL-ASP-GLU-OH
  • ALPHA-NAAG
  • AC-ASP-GLU
  • AC-ASP-GLU H2O
  • AC-ASP-GLU-OH
  • n-acetyl-1-aspartylglutamicacid
  • isospaglumic acid
  • Naaxia
  • 2-[(2-acetamido-3-carboxy-propanoyl)amino]pentanedioic acid
  • ACETYL-D-E
  • NAAG, Spaglumic acid
  • NAAGA
  • ZY-15106
  • 6-AMINO-1-HEXANETHIOL,HCL
  • (S)-2-((S)-2-acetaMido-3-carboxypropanaMido)pentanedioic acid
  • NAAG - CAS 3106-85-2 - Calbiochem
  • N-acetyl aspartyl-glutaMic acid USP/EP/BP
  • L-Glutamic acid, N-acetyl-L-α-aspartyl-
  • (S)-2-((S)-2-Acetamido-3-carboxypropanamido)pentanedioic acid[Spaglumic Acid
  • α-NAAG
  • 3106-85-2
  • 3106-86-2
  • C11H16N2O8