ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
- Product Name
- ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
- CAS No.
- 30148-21-1
- Chemical Name
- ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
- Synonyms
- RGW 811;RARECHEM AL BI 0638;1--1H--2-MethyliMidazoleethyl forMate;ETHYL 1-METHYLIMIDAZOLE-2-CARBOXYLATE;1--1H- MethyliMidazole-2-ethyl forMate;Ethyl1-Methylimidazole-2-carboxylate>2-(Ethoxycarbonyl)-1-methyl-1H-imidazole;Ethyl1-methylimidazole-2-carboxylate,95%;ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE;Ethyl 1-methyl-1H-imidazole-2-carboxylate ,97%
- CBNumber
- CB1751835
- Molecular Formula
- C7H10N2O2
- Formula Weight
- 154.17
- MOL File
- 30148-21-1.mol
ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE Property
- Melting point:
- 29-31°C
- Boiling point:
- 110-111°C/ 0.5 mmHg
- Density
- 1.14±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in dichloromethane, ether, ethyl acetate and methanol.
- form
- Solid
- pka
- 4.00±0.25(Predicted)
- color
- White Crystalline
- InChI
- InChI=1S/C7H10N2O2/c1-3-11-7(10)6-8-4-5-9(6)2/h4-5H,3H2,1-2H3
- InChIKey
- NOTZYDYZBOBDFE-UHFFFAOYSA-N
- SMILES
- C1(C(OCC)=O)N(C)C=CN=1
- CAS DataBase Reference
- 30148-21-1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E1114
- Product name
- Ethyl 1-Methylimidazole-2-carboxylate
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- E1114
- Product name
- Ethyl 1-Methylimidazole-2-carboxylate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- E1114
- Product name
- Ethyl 1-Methylimidazole-2-carboxylate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $240
- Updated
- 2025/07/31
- Product number
- E925100
- Product name
- Ethyl 1-Methylimidazole-2-carboxylate
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 42936
- Product name
- Ethyl1-methylimidazole-2-carboxylate,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 5G
- Price
- $72.8
- Updated
- 2021/12/16
ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE Chemical Properties,Usage,Production
Chemical Properties
White Crystalline Solid
Uses
Ethyl 1-methylimidazole-2-carboxylate is used as a synthetic intermediate for solid phase synthesis of polyamides containing imidazole.
Uses
Ethyl 1-methyl-1H-imidazole-2-carboxylate is a useful synthetic intermediate for solid phase synthesis of polyamides containing imidazole.
Synthesis
616-47-7
541-41-3
30148-21-1
Synthesis of ethyl 1-methyl-1H-imidazole-2-carboxylate: triethylamine (3.40 mL, 24.4 mmol) and ethyl chloroformate (2.34 mL, 24.4 mmol) were added drop-wise to a solution of 1-methyl-1H-imidazole (1.00 g, 12.2 mmol) in acetonitrile (4.0 mL) at 0 °C. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by fast column chromatography (silica gel as stationary phase and hexane/ethyl acetate as eluent) to afford ethyl 1-methyl-1H-imidazole-2-carboxylate (1.50 g, 9.73 mmol, 80% yield) as a white solid. The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3) and ESI-MS: 1H-NMR δ 1.42 (3H, t, J = 7.2 Hz), 4.01 (3H, s), 4.40 (2H, q, J = 7.2 Hz), 7.01-7.03 (1H, m), 7.13-7.15 (1H, m); ESI-MS m /z = 155 (M + H)+.
References
[1] Journal of the American Chemical Society, 1996, vol. 118, # 26, p. 6141 - 6146
[2] Patent: EP3263565, 2018, A1. Location in patent: Paragraph 0386; 0387
[3] Patent: JP2017/66077, 2017, A. Location in patent: Page/Page column 7; 8; 9; 10; 11
[4] Patent: WO2005/33077, 2005, A1. Location in patent: Page/Page column 53
[5] Patent: WO2004/58763, 2004, A1. Location in patent: Page 43
ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE Suppliers
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View Lastest Price from ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE manufacturers
- Product
- ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE 30148-21-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-18
- Product
- ETHYL 1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE 30148-21-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20