ChemicalBook > CAS DataBase List > ISOXAZOLE-5-CARBOXYLIC ACID

ISOXAZOLE-5-CARBOXYLIC ACID

Product Name
ISOXAZOLE-5-CARBOXYLIC ACID
CAS No.
21169-71-1
Chemical Name
ISOXAZOLE-5-CARBOXYLIC ACID
Synonyms
AKOS PAO-1371;BUTTPARK 27\08-41;5-Carboxyisoxazole;TIMTEC-BB SBB004319;5-Carboxy-1,2-oxazole;Isoxazol-5-carbonsaeure;Isoxazole 5-formic acid;Isozole-5-carboxylic acid;5-Isoxazolecarboxylic acid;Isoxazol-5-carboxylic acid
CBNumber
CB1758728
Molecular Formula
C4H3NO3
Formula Weight
113.07
MOL File
21169-71-1.mol
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ISOXAZOLE-5-CARBOXYLIC ACID Property

Melting point:
144-148 °C(lit.)
Boiling point:
211.74°C (rough estimate)
Density 
1.5808 (rough estimate)
refractive index 
1.4543 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Powder
pka
2.29±0.10(Predicted)
color 
Slightly yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C4H3NO3/c6-4(7)3-1-2-5-8-3/h1-2H,(H,6,7)
InChIKey
MIIQJAUWHSUTIT-UHFFFAOYSA-N
SMILES
O1C(C(O)=O)=CC=N1
CAS DataBase Reference
21169-71-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-25-24-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
636258
Product name
Isoxazole-5-carboxylic acid
Purity
97%
Packaging
5g
Price
$213
Updated
2023/06/20
TCI Chemical
Product number
I1227
Product name
Isoxazole-5-carboxylic Acid
Purity
min. 97.0 %
Packaging
1G
Price
$46
Updated
2025/07/31
TCI Chemical
Product number
I1227
Product name
Isoxazole-5-carboxylic Acid
Purity
min. 97.0 %
Packaging
5G
Price
$138
Updated
2025/07/31
TRC
Product number
I918110
Product name
5-IsoxazolecarboxylicAcid
Packaging
25g
Price
$825
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0030226
Product name
ISOXAZOLE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
5G
Price
$1005.43
Updated
2021/12/16
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ISOXAZOLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

slightly yellow powder

Uses

Reaction conditions were found to allow the exclusive formation of isoxazole-5-carboxylic acid derivatives by conjugate addition, in acidic medium, of hydroxylamine to β-alkoxyvinyl trichloromethyl ketone in synthesis and reactivity of isoxazoles. Isoxazole-5-carboxylic acid participates in the Synthesis and evaluation of acylguanidine FXa inhibitors. 1, 1, 1-trichloro-4-methoxy-3-penten-2-one postulated in the preparation of isoxazole-5-carboxylic acid from trichloroacetyl chloride, ethyl vinyl ether and hydroxylamine is developed in a fully saturated nitrogen atom theerefore there is no possibility of conjugation with 4- substituents.

General Description

Isoxazole-5-carboxylic acid can be obtained via dehydration of 5-trichloromethylisoxazole.

ISOXAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Hexane Trifluoroacetic anhydride Diethyl ether Lithium Aluminum Hydride Dichloromethane Methanol Hydroxylamine hydrochloride Pyridine Thionyl chloride Sulfuric acid Trichloroacetic acid

Preparation Products

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ISOXAZOLE-5-CARBOXYLIC ACID Suppliers

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View Lastest Price from ISOXAZOLE-5-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co
Product
ISOXAZOLE-5-CARBOXYLIC ACID 21169-71-1
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10tons
Release date
2018-12-23

21169-71-1, ISOXAZOLE-5-CARBOXYLIC ACIDRelated Search:

isoxazol-5-amine ISOXAZOL-3-YLMETHYL-METHYL-AMINE ISOXAZOLE-5-CARBONYL CHLORIDE C-ISOXAZOL-3-YL-METHYLAMINE METHYL ISOXAZOLE-5-CARBOXYLATE ISOXAZOLIDIN-3-ONE 4-Aminoisoxazole Methyl isonicotinate Ethyl isonicotinate 2-[[(3aS,4R,6S,6aR)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol Isoxazol-4-ylmethanamine oxalate ISOXAFLUTOLE ISOXAZOLO[5,4-B]PYRIDIN-3-YLAMINE 5-Isoxazolecarboxylicacid,ethylester(9CI) 1,2-oxazol-3-ylMethanaMine hydrochloride 3-AMINOISOXAZOLO[4,5-B]PYRAZINE Isoxazole-4-boronicacid C-ISOXAZOL-5-YL-METHYLAMINE HYDROCHLORIDE

  • TIMTEC-BB SBB004319
  • AKOS PAO-1371
  • ISOXAZOLE-5-CARBOXYLIC ACID
  • BUTTPARK 27\08-41
  • 5-Isoxazolecarboxylic acid
  • Isoxazole-5-carboxylic acid 98%
  • Isoxazole-5-carboxylic acid ,98%
  • 5-Carboxyisoxazole, 1,2-Oxazole-5-carboxylic acid, 5-Carboxy-1,2-oxazole
  • 1,2-oxazole-5-carboxylic acid
  • 5-Carboxy-1,2-oxazole
  • 5-Carboxyisoxazole
  • 5-isoxazolylcarboxylic acid
  • Isoxazol-5-carbonsaeure
  • Isozole-5-carboxylic acid
  • Isoxazole 5-formic acid
  • 5-Isoxazolecarboxylic acid (7CI, 8CI, 9CI, ACI)
  • Isoxazol-5-carboxylic acid
  • 21169-71-1
  • 21169-71-7
  • C4H3NO
  • ARYL ACID
  • Building Blocks
  • Isoxazoles
  • Heterocyclic Building Blocks
  • carboxylic acid
  • Oxazole&Isoxazole
  • Building Blocks
  • Heterocyclic Building Blocks
  • Isoxazoles