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Orciprenaline

Product Name
Orciprenaline
CAS No.
586-06-1
Chemical Name
Orciprenaline
Synonyms
orciprenaline;Orciprenaline USP/EP/BP;Orciprenaline & Orciprenaline Sulfate;Metaproterenol (base and/or unspecified salts);1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol;5-[1-hydroxy-2-(isopropylamino)ethyl]resorcinol;5-[2-(Isopropylamino)-1-hydroxyethyl]-1,3-benzenediol;3,5-Dihydroxy-a-[(isopropylamino)methyl]benzyl alcohol;5-(1-hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol;3,5-Dihydroxy-α-[(isopropylamino)methyl]benzyl alcohol
CBNumber
CB1855195
Molecular Formula
C11H17NO3
Formula Weight
211.26
MOL File
586-06-1.mol
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Orciprenaline Property

Melting point:
100°
Boiling point:
350.94°C (rough estimate)
Density 
1.1240 (rough estimate)
refractive index 
1.5718 (estimate)
pka
9.11±0.10(Predicted)
CAS DataBase Reference
586-06-1(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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Orciprenaline Chemical Properties,Usage,Production

Originator

Alupent, Boehringer Ingelheim ,W. Germany ,1961

Uses

Bronchodilator.

Manufacturing Process

In an initial operation, 3,5-diacetoxyacetophenone was reacted first with bromine and then with isopropylamine to give 1-(3,5-dihydroxyphenyl)-2- isopropylaminoethanone.
59 g of 1-(3,5-dihydroxy-phenyl)-2-isopropylaminoethanone (free base) were dissolved in 590 cc of methanol, and the solution was hydrogenated in the presence of about 80 g Raney nickel at room temperature and under a pressure of 5 atm. Hydrogen absorption was terminated after a few minutes. The catalyst was separated by vacuum filtration, and the filtrate, an ethanolic solution of 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethane, was admixed with the calculated amount of an alcoholic 20% sulfuric acid solution. A crystalline precipitate formed which was filtered off and washed with alcohol. For purification, the product was dissolved in water and the solution was filtered through iron-free charcoal.
Thereafter, the filtrate was evaporated to dryness in vacuo and the residue was taken up in alcohol. The crystalline precipitate which separated out after some standing was separated by vacuum filtration and washed with alcohol. After recrystallization from 90% alcohol, 61 g (83.2% of theory) of 1-(3,5- dihydroxyphenyl)-1-hydroxy-2-isopropylamino-ethane sulfate, MP 202° to 203°C, was obtained.

Therapeutic Function

Bronchodilator

Orciprenaline Preparation Products And Raw materials

Raw materials

Preparation Products

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Orciprenaline Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
1938
Advantage
70
BOC Sciences
Tel
Email
info@bocsci.com
Country
United States
ProdList
9942
Advantage
65
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725;010-86181995
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12341
Advantage
58
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4938
Advantage
55
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196;028-84555506- ;028-84555506-
Fax
QQ:800101999
Email
cdhxsj@163.com;cdhxsj@163.com;cdhxsj@163.com
Country
China
ProdList
13363
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432-
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
13966
Advantage
53
Alta Scientific Co., Ltd.
Tel
022-65378550- ;022-65378550-
Fax
022-2532-9655
Email
sales@altascientific.com;marketing@altascientific.com
Country
China
ProdList
9051
Advantage
55
West Asia Chemical Technology (Shandong) Co. Ltd
Fax
0539-6365991
Email
3007715519@qq.com;3007715519@qq.com
Country
China
ProdList
27466
Advantage
60
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799(To 20)
Fax
0539-6362799(To 20)
Email
861669111@qq.com
Country
China
ProdList
10001
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
Fax
18327183813
Email
2853530914@qq.com
Country
China
ProdList
2779
Advantage
58
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View Lastest Price from Orciprenaline manufacturers

Dideu Industries Group Limited
Product
Orciprenaline USP/EP/BP 586-06-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-05-28
Shaanxi Dideu Medichem Co. Ltd
Product
Orciprenaline 586-06-1
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-04-24
career henan chemical co
Product
Orciprenaline 586-06-1
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

586-06-1, OrciprenalineRelated Search:


  • 5-[1-hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol
  • 5-(1-hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol
  • orciprenaline
  • 1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol
  • 1,3-Benzenediol, 5-1-hydroxy-2-(1-methylethyl)aminoethyl-
  • 1,3-Benzenediol, 5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]- (9CI)
  • 3,5-Dihydroxy-a-[(isopropylamino)methyl]benzyl alcohol
  • Benzyl alcohol, 3,5-dihydroxy-a-[(isopropylamino)methyl]- (6CI, 8CI)
  • 3,5-dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol
  • 3,5-dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol
  • 5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-3-benzenediol
  • 5-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,3-benzenediol
  • 3,5-Dihydroxy-α-[(isopropylamino)methyl]benzyl alcohol
  • 5-[2-(Isopropylamino)-1-hydroxyethyl]-1,3-benzenediol
  • 5-[1-hydroxy-2-(isopropylamino)ethyl]resorcinol
  • Orciprenaline & Orciprenaline Sulfate
  • Metaproterenol (base and/or unspecified salts)
  • Orciprenaline USP/EP/BP
  • 586-06-1
  • Orciprenaline