10H-pyrido(3,2-b)(1,4)benzothiazine

Product Name: 10H-pyrido(3,2-b)(1,4)benzothiazine
CAS No.: 261-96-1
Chemical Name: 10H-pyrido(3,2-b)(1,4)benzothiazine
Synonyms: NSC 277720;1-Azaphenothiazine;1-Azaphenothiazine>Isothipendyl Impurity 1;Isothipendyl Impurity 2;10H-benzo[e]pyrido[3,2-b][1;PYRIDO[3,2-B][1,4]BENZOTHIAZINE;1H-Pyrido[3,2-b][1,4]benzothiazine;10H-pyrido(3,2-b)(1,4)benzothiazine;10H-benzo[e]pyrido[3,2-b][1,4]thiazine
CBNumber: CB1875186
Molecular Formula: C11H8N2S
Formula Weight: 200.26
MOL File: 261-96-1.mol

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10H-pyrido(3,2-b)(1,4)benzothiazine Property

Melting point:: 110.0 to 114.0 °C
Boiling point:: 370°C(lit.)
Density: 1.293
storage temp.: Sealed in dry,Room Temperature
solubility: Dichloromethane (Slightly), DMSO (Slightly)
pka: 4.24±0.20(Predicted)
form: Solid
color: Yellow to Dark Yellow
InChI: InChI=1S/C11H8N2S/c1-2-5-9-8(4-1)13-11-10(14-9)6-3-7-12-11/h1-7H,(H,12,13)
InChIKey: UKDZROJJLPDLDO-UHFFFAOYSA-N
SMILES: S1C2=CC=CC=C2NC2=NC=CC=C12

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Safety

HS Code: 2934.99.4400

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2862
Product name: 1-Azaphenothiazine
Purity: >98.0%(GC)(T)
Packaging: 200mg
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: A2862
Product name: 1-Azaphenothiazine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $224
Updated: 2025/07/31

TRC

Product number: P991655
Product name: 10H-Pyrido[3,2-b][1,4]benzothiazine
Packaging: 1g
Price: $250
Updated: 2021/12/16

TRC

Product number: P991655
Product name: 10H-Pyrido[3,2-b][1,4]benzothiazine
Packaging: 10g
Price: $495
Updated: 2021/12/16

AK Scientific

Product number: X4630
Product name: 10H-Pyrido(3,2-b)(1,4)benzothiazine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

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10H-pyrido(3,2-b)(1,4)benzothiazine Chemical Properties,Usage,Production

Uses

10H-Pyrido[3,2-b][1,4]benzothiazine has potential anti-cancer ability as seen through studies.

Synthesis

95873-97-5

261-96-1

General procedure for the synthesis of azaphenothiazine from the compound (CAS: 95873-97-5): 15.0 g (119.82 mmol) of intermediate (C) was suspended with 4.36 g (119.82 mmol) of hydrochloric acid in 470 mL of ethanol and the reaction was carried out at reflux for 12 h at 70 °C under nitrogen protection. After completion of the reaction, extraction was carried out with dichloromethane and distilled water and the organic layer was filtered through silica gel. After concentrating the organic solvent, it was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 7:3, v/v) to give 20.64 g of intermediate (D) in 86% yield.

References

[1] Patent: KR2015/12906, 2015, A. Location in patent: Paragraph 0197; 0204-0205
[2] Journal of the American Chemical Society, 1958, vol. 80, p. 1651,1653

10H-pyrido(3,2-b)(1,4)benzothiazine Preparation Products And Raw materials

Raw materials

Preparation Products

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10H-pyrido(3,2-b)(1,4)benzothiazine Suppliers

Americas 1 Canada 1 China 98 Europe 1 Germany 1 India 10 Japan 1 United States 7 Global 120

Alchem Pharmtech,Inc.

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Waterstone Technology, LLC

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View Lastest Price from 10H-pyrido(3,2-b)(1,4)benzothiazine manufacturers

Beijing CosmicKoda Chemical Technology Co.,Ltd

Product: 10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: bulk production
Release date: 2025-11-26

Career Henan Chemical Co

Product: 10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

261-96-1, 10H-pyrido(3,2-b)(1,4)benzothiazineRelated Search:

1H-1,4-Diazepine-1-ethanol, hexahydro-4-(3-(3-chloro-10H-pyrido(3,2-b) (1,4)benzothiazin-10-yl)propyl)-, dihydrochloride 10-(4-BROMOBENZYL)-10H-PYRIDO[3,2-B][1,4]BENZOTHIAZINE Cloxypendyl 10-(2-PROPYNYL)-10H-PYRIDO[3,2-B][1,4]BENZOTHIAZINE pipazetate hydrochloride isothipendyl hydrochloride 10-(2-CHLORO-6-FLUOROBENZYL)-10H-PYRIDO[3,2-B][1,4]BENZOTHIAZINE 10H-Pyrido(3,2-b)(1,4)benzothiazine, 3-chloro-10-((2-(dimethylamino)-1 -methyl)ethyl)-, hydrochloride Prothipendyl 10H-pyrido(3,2-b)(1,4)benzothiazine ISOTHIPENDYL Oxypendyl pipazethate

PYRIDO[3,2-B][1,4]BENZOTHIAZINE

1-Azaphenothiazine

1H-Pyrido[3,2-b][1,4]benzothiazine

10H-pyrido(3,2-b)(1,4)benzothiazine

10H-benzo[e]pyrido[3,2-b][1

NSC 277720

10H-Benzo[b]pyrido[2,3-e][1,4]thiazine

10H-benzo[e]pyrido[3,2-b][1,4]thiazine

1-Azaphenothiazine&gt

Isothipendyl Impurity 2

Isothipendyl Impurity 1

9-thia-2,4-diazatricyclo[8.4..3,?]tetradeca-1(14),3,5,7,1,12-hexaene

10H-Pyrido[3,2-b][1,4]benzothiazine (6CI, 7CI, ACI)

261-96-1