ChemicalBook > CAS DataBase List > Mubritinib

Mubritinib

Product Name
Mubritinib
CAS No.
366017-09-6
Chemical Name
Mubritinib
Synonyms
CS-522;TAK 165;MUBRITINIB;TAK165;TAK-165;Mubritinib(TAK 165);Mubritinib USP/EP/BP;(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1H-1,2,3-Triazole, 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-
CBNumber
CB21011746
Molecular Formula
C25H23F3N4O2
Formula Weight
468.47
MOL File
366017-09-6.mol
More
Less

Mubritinib Property

Melting point:
158.0 to 162.0 °C
Boiling point:
620.9±65.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO : 50 mg/mL (106.73 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
pka
1.45±0.10(Predicted)
form 
powder to crystal
color 
White to Gray to Brown
More
Less

Safety

HS Code 
2934.99.4400
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1312
Product name
Mubritinib
Purity
≥98% (HPLC)
Packaging
5MG
Price
$74.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1312
Product name
Mubritinib
Purity
≥98% (HPLC)
Packaging
25MG
Price
$289
Updated
2024/03/01
TCI Chemical
Product number
M3058
Product name
Mubritinib
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$185
Updated
2024/03/01
TCI Chemical
Product number
M3058
Product name
Mubritinib
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$552
Updated
2024/03/01
Cayman Chemical
Product number
12096
Product name
Mubritinib
Purity
≥98%
Packaging
5mg
Price
$39
Updated
2024/03/01
More
Less

Mubritinib Chemical Properties,Usage,Production

Uses

Treatment of cancer.

Uses

Mubritinib is used in selective targeting of CTNNB1-, KRAS-or MYC-driven human cancer cell growth by combinations of existing drugs

Biological Activity

Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .

storage

Store at +4°C

Mubritinib Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Mubritinib Suppliers

Americas 1 China 114 Europe 2 Germany 1 India 2 Japan 1 United Kingdom 4 United States 21 Global 146
ACTIVATE SCIENTIFIC GmbH
Tel
--
Fax
--
Email
info@activate-scientific.com
Country
Germany
ProdList
2856
Advantage
61
More
Less

View Lastest Price from Mubritinib manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Mubritinib 366017-09-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Mubritinib 366017-09-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Dideu Industries Group Limited
Product
Mubritinib 366017-09-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-06

366017-09-6, MubritinibRelated Search:

2-Methoxyethanol tert-Butylchlorodiphenylsilane Anisole Nizatidine Dasatinib monohydrate PHENYL VALERATE VINYL PROPIONATE 1,4-Adamantandiol 4-Methoxyphenylacetone (Trifluoromethoxy)benzene Lapatinib Gefitinib Imatinib Pralmorelin Sunitinib Phenylhydrazine Vinyl ester resin Trifluoromethyl

  • MUBRITINIB
  • 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
  • TAK 165
  • Mubritinib(TAK 165)
  • CS-522
  • TAK165;TAK-165
  • (E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
  • 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165)
  • Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
  • (E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole
  • 1H-1,2,3-Triazole, 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-
  • Mubritinib USP/EP/BP
  • 366017-09-6
  • C25H23F3N4O2
  • Inhibitors