ChemicalBook > CAS DataBase List > (R)-(-)-alpha-Methoxyphenylacetic acid

(R)-(-)-alpha-Methoxyphenylacetic acid

Product Name
(R)-(-)-alpha-Methoxyphenylacetic acid
CAS No.
3966-32-3
Chemical Name
(R)-(-)-alpha-Methoxyphenylacetic acid
Synonyms
(R)-2-Methoxy-2-phenylacetic acid;(R)-(-)-α-Methoxyphenylacetic Acid;(R)-(-)-αBenzeneacetic acid, .a;O-METHYL-D-MANDELIC ACID;O-Methyl-(R)-mandelicacid;Acetic acid, methoxyphenyl;(-)-Methoxyphenylacetic acid;(1)-(Methoxy)phenylacetic acid;(methyloxy)(phenyl)acetic acid
CBNumber
CB2105770
Molecular Formula
C9H10O3
Formula Weight
166.17
MOL File
3966-32-3.mol
More
Less

(R)-(-)-alpha-Methoxyphenylacetic acid Property

Melting point:
66-68 °C(lit.)
alpha 
-160.4 º (C=1, MEOH)
Boiling point:
164-166°C 18mm
Density 
1.1708 (rough estimate)
refractive index 
-147 ° (C=0.5, EtOH)
Flash point:
164-166°C/18mm
storage temp. 
2-8°C
solubility 
Chloroform, Ethanol, Methanol
pka
3.10±0.10(Predicted)
form 
Fine Crystalline Powder or Needles
color 
White
optical activity
[α]20/D -150±3°, c = 0.5% in ethanol
BRN 
3589257
CAS DataBase Reference
3966-32-3(CAS DataBase Reference)
NIST Chemistry Reference
(R)-(-)-«alpha»-methoxyphenylacetic acid(3966-32-3)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29189900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
248967
Product name
(R)-(?)-α-Methoxyphenylacetic acid
Purity
99%
Packaging
1g
Price
$208
Updated
2024/03/01
Sigma-Aldrich
Product number
65209
Product name
(R)-(?)-α-Methoxyphenylacetic acid
Purity
for chiral derivatization, ≥99.0%
Packaging
1g
Price
$310
Updated
2022/05/15
TCI Chemical
Product number
M0830
Product name
(R)-(-)-alpha-Methoxyphenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$39
Updated
2024/03/01
TCI Chemical
Product number
M0830
Product name
(R)-(-)-alpha-Methoxyphenylacetic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$123
Updated
2024/03/01
Alfa Aesar
Product number
L08719
Product name
(R)-(-)-alpha-Methoxyphenylacetic acid, 99%
Packaging
250mg
Price
$37.65
Updated
2024/03/01
More
Less

(R)-(-)-alpha-Methoxyphenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powder or needles

Uses

(R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.

General Description

(R)-(?)-α-Methoxyphenylacetic acid is a chiral derivatizating agent, which is employed for derivatizing enantiomers into diastereoisomers.

Purification Methods

Purify the acids by recrystallising from *C6H6/pet ether (b 80-100o). [Neilson & Peters J Chem Soc 1519 1962, Weizmann et al. J Am Chem Soc 70 1153 1948, Pirie & Smith J Chem Soc 338 1932, NMR: Dale & Mosher J Am Chem Soc 9 5 512 1973, for resolution: Roy & Deslongchamps Can J Chem 63 651 1985, Trost et al. J Am Chem Soc 1 0 8 4974 1986.] The racemic mixture has m 72o, b 121-122o/0.4mm, 165o/18mm (from pet ether) [Braun et al. Chem Ber 6 3 2847 1930]. [Beilstein 10 IV 566.]

(R)-(-)-alpha-Methoxyphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(-)-alpha-Methoxyphenylacetic acid Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
More
Less

View Lastest Price from (R)-(-)-alpha-Methoxyphenylacetic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
(R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Henan Aochuang Chemical Co.,Ltd.
Product
(R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Career Henan Chemical Co
Product
(R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

3966-32-3, (R)-(-)-alpha-Methoxyphenylacetic acidRelated Search:


  • (R)-(-)-METHOXYPHENYLACETIC ACID
  • O-METHYL-D-MANDELIC ACID
  • (R)-(-)-ALPHA-METHOXYPHENYLACETIC ACID
  • (R)-ALPHA-METHOXYPHENYLACETIC ACID
  • (R)-(-)-A-METHOXYPHENYLACETIC ACID
  • Benzeneacetic acid, alpha-methoxy-, (R)-
  • Acetic acid, methoxyphenyl- (8CI)
  • Benzeneacetic acid, .a
  • (<i>R</i>)-(-)-&alpha
  • R-MINUS-A-METHOXYPHENYL ACETIC ACID
  • O-Methyl-(R)-mandelicacid
  • (r)-(-)-à-methoxyphenylacetic acid
  • (R)-(-)-ALPHA-METHOXYPHENYLACETIC ACID 99%
  • (R)-(-)-ɑ-Methoxyphenylacetic acid, 99%
  • (2R)-2-Methoxy-2-phenylacetic acid
  • (R)-α-Methoxybenzeneacetic acid
  • (αR)-α-Methoxybenzeneacetic acid
  • [R,(-)]-α-Methoxybenzeneacetic acid
  • (R)-(-)-alpha-Methoxyphenylacetic acid,99%
  • (R)-()-α-Methoxyphenylacetic acid,O-Methyl-D-mandelic acid
  • (R)-(-)-alpha-Methoxyphenylacetic acid, 99% 1GR
  • (R)-2-Methoxy-2-phenylacetic acid
  • (1)-(Methoxy)phenylacetic acid
  • (methyloxy)(phenyl)acetic acid
  • 2-methoxy-2-phenyl-ethanoic acid
  • Acetic acid, methoxyphenyl
  • (R)-(-)-α-MethoxyphenylaceticAcid&gt
  • Benzeneacetic acid, α-methoxy-, (αR)-
  • (R)-(-)-α-Methoxyphenylacetic Acid
  • ?-(-)-alpha-Methoxyphenylacetic acid
  • (2S)-Methoxy(phenyl)acetic acid
  • (-)-Methoxyphenylacetic acid
  • 3966-32-3
  • e.e. / Absolute Conefiguration Determination (NMR)
  • Enantiomer Excess & Absolute Conefiguration Determination
  • Chiral Building Blocks
  • Carboxylic Acids (Chiral)
  • Derivatization Reagents
  • Chiral Resolving Reagents
  • Analytical Chromatography Product Catalog
  • Chiral Derivatization
  • Chiral Resolution Reagents
  • Asymmetric Synthesis
  • Analytical Chemistry
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • e.e. / Absolute Configuration Determination (NMR)
  • Enantiomer Excess & Absolute Configuration Determination
  • Synthetic Organic Chemistry