(R)-(-)-alpha-Methoxyphenylacetic acid
- Product Name
- (R)-(-)-alpha-Methoxyphenylacetic acid
- CAS No.
- 3966-32-3
- Chemical Name
- (R)-(-)-alpha-Methoxyphenylacetic acid
- Synonyms
- (R)-2-Methoxy-2-phenylacetic acid;(R)-(-)-α-Methoxyphenylacetic Acid;(R)-(-)-αBenzeneacetic acid, .a;O-METHYL-D-MANDELIC ACID;O-Methyl-(R)-mandelicacid;Acetic acid, methoxyphenyl;(-)-Methoxyphenylacetic acid;(1)-(Methoxy)phenylacetic acid;(methyloxy)(phenyl)acetic acid
- CBNumber
- CB2105770
- Molecular Formula
- C9H10O3
- Formula Weight
- 166.17
- MOL File
- 3966-32-3.mol
(R)-(-)-alpha-Methoxyphenylacetic acid Property
- Melting point:
- 66-68 °C(lit.)
- alpha
- -160.4 º (C=1, MEOH)
- Boiling point:
- 164-166°C 18mm
- Density
- 1.1708 (rough estimate)
- refractive index
- -147 ° (C=0.5, EtOH)
- Flash point:
- 164-166°C/18mm
- storage temp.
- 2-8°C
- solubility
- Chloroform, Ethanol, Methanol
- pka
- 3.10±0.10(Predicted)
- form
- Fine Crystalline Powder or Needles
- color
- White
- optical activity
- [α]20/D -150±3°, c = 0.5% in ethanol
- BRN
- 3589257
- CAS DataBase Reference
- 3966-32-3(CAS DataBase Reference)
- NIST Chemistry Reference
- (R)-(-)-«alpha»-methoxyphenylacetic acid(3966-32-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 248967
- Product name
- (R)-(?)-α-Methoxyphenylacetic acid
- Purity
- 99%
- Packaging
- 1g
- Price
- $208
- Updated
- 2024/03/01
- Product number
- 65209
- Product name
- (R)-(?)-α-Methoxyphenylacetic acid
- Purity
- for chiral derivatization, ≥99.0%
- Packaging
- 1g
- Price
- $310
- Updated
- 2022/05/15
- Product number
- M0830
- Product name
- (R)-(-)-alpha-Methoxyphenylacetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $39
- Updated
- 2024/03/01
- Product number
- M0830
- Product name
- (R)-(-)-alpha-Methoxyphenylacetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $123
- Updated
- 2024/03/01
- Product number
- L08719
- Product name
- (R)-(-)-alpha-Methoxyphenylacetic acid, 99%
- Packaging
- 250mg
- Price
- $37.65
- Updated
- 2024/03/01
(R)-(-)-alpha-Methoxyphenylacetic acid Chemical Properties,Usage,Production
Chemical Properties
white fine crystalline powder or needles
Uses
(R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.
General Description
(R)-(?)-α-Methoxyphenylacetic acid is a chiral derivatizating agent, which is employed for derivatizing enantiomers into diastereoisomers.
Purification Methods
Purify the acids by recrystallising from *C6H6/pet ether (b 80-100o). [Neilson & Peters J Chem Soc 1519 1962, Weizmann et al. J Am Chem Soc 70 1153 1948, Pirie & Smith J Chem Soc 338 1932, NMR: Dale & Mosher J Am Chem Soc 9 5 512 1973, for resolution: Roy & Deslongchamps Can J Chem 63 651 1985, Trost et al. J Am Chem Soc 1 0 8 4974 1986.] The racemic mixture has m 72o, b 121-122o/0.4mm, 165o/18mm (from pet ether) [Braun et al. Chem Ber 6 3 2847 1930]. [Beilstein 10 IV 566.]
(R)-(-)-alpha-Methoxyphenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-(-)-alpha-Methoxyphenylacetic acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23680
- Advantage
- 75
View Lastest Price from (R)-(-)-alpha-Methoxyphenylacetic acid manufacturers
- Product
- (R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-09-28
- Product
- (R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- (R)-(-)-alpha-Methoxyphenylacetic acid 3966-32-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-24