Hydroxyapatite

ChemicalBook > CAS DataBase List > Hydroxyapatite

Product Name: Hydroxyapatite
CAS No.: 1306-06-5
Chemical Name: Hydroxyapatite
Synonyms: HA;TRICALCIUM PHOSPHATE;CALCIUM HYDROXYAPATITE;HYDROXYLAPATITE;TRIBASIC CALCIUM PHOSPHATE;Apatite HAP;DURAPATITE;CALCIUM PHOSPHATE HYDROXIDE;BONE ASH;APATITE HAP, MONOCLINIC
CBNumber: CB2131094
Molecular Formula: Ca5HO13P3
Formula Weight: 502.31
MOL File: 1306-06-5.mol

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Hydroxyapatite Property

Melting point:: 1100 °C(lit.)
Density: 3.076 g/cm3(Temp: 18 °C)
storage temp.: 2-8°C
solubility: H₂O: 0.3 mg/mL, clear, colorless
form: solid
color: White
Water Solubility: insoluble H2O [MER06]
Merck: 13,3500
CAS DataBase Reference: 1306-06-5(CAS DataBase Reference)
EPA Substance Registry System: Hydroxylapatite (Ca5(OH)(PO4)3) (1306-06-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: MY8434000
F: 3-10
TSCA: Yes
HS Code: 28352600
Hazardous Substances Data: 1306-06-5(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 391947
Product name: Hydroxylapatite, fast flow
Packaging: 100g
Price: $701
Updated: 2024/03/01

Sigma-Aldrich

Product number: 21223
Product name: Hydroxyapatite
Purity: purum p.a., ≥90% (as Ca3(PO4)2, KT)
Packaging: 1kg
Price: $194
Updated: 2024/03/01

Sigma-Aldrich

Product number: 04238
Product name: Hydroxyapatite
Purity: ≥90% (calculated on glowed substance)
Packaging: 1kg
Price: $136
Updated: 2024/03/01

Alfa Aesar

Product number: J60076
Product name: Hydroxylapatite, fast flow
Packaging: 10g
Price: $85.65
Updated: 2024/03/01

Alfa Aesar

Product number: J60076
Product name: Hydroxylapatite, fast flow
Packaging: 50g
Price: $373
Updated: 2024/03/01

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Hydroxyapatite Chemical Properties,Usage,Production

Description

Calcium hydroxyapatite has a unique structure in that it is conductive along the hydroxide channels. OH^- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on the c-axis and charge-carrying protons are responsible for the observed conductivities in M10(PO4)6(OH)2. The H⁺ migration between the electroattractive ion (O2) to give molecular H2O in matrix channels carries charge and the resulting conductivity.
The unit cell consists of two triangular prismatic subcells forming a rhombic prism with vertical sides. There are two horizontal mirror planes at the OH levels of 1/4 and 3/4 of the c-axis. In addition, there is a center of inversion exactly in the center of each vertical face of each subcell.

Chemical Properties

Tricalcium phosphate is an odorless and tasteless powder that is stable in air. Tribasic calcium phosphate consists of a variable mixture of calcium phosphates having the approximate composition of 10CaO·3P2O5·H2O.

Chemical Properties

white powder

Occurrence

Occurs in nature as the minerals: oxydapatit, voelicherite, whitlockite.

Uses

Hydroxyapatite and tricalcium phosphate are bioactive ceramic materials and they find applications as bone grafts, fillers and coating material for metal implants.

Uses

Prosthetic aid (artificial bone and teeth).

Uses

In the 1970s, it was found that sintered calcium hydroxyapatite, (Ca10(PO4)6(OH)2 (abbreviated as CaHap), possessed excellent biocompatibility and nontoxicity with femur and mandible bones. Since then, CaHap has been used as a biomaterial for artificial teeth and bones and as a filler for cements and polymers. Today, bone fillers made of CaHap are widely used in the medical and dental fields. In the 1980s, it was found that sintered CaHap has a good compatibility with skin tissues. Hence, percutaneous devices based on CaHap have been developed and applications have included continuous ambulatory peritoneal dialysis and intravenous hyperalimentation systems, blood pressure measurement and blood access for nutrition. Recently, many researchers have studied the chemistry of apatites, particularly CaHap, and have found various applications, such as artificial teeth and bones, ion exchangers, adsorbents for chromatography to separate proteins and enzymes, catalysts, ionic conductors, temperature and gas sensors, etc.

Preparation

The technical product is also known as “bone ash.” Commercial preparation from phosphate rock.

Definition

The major constituent of bone and tooth mineral. It is finely divided, crystalline, nonstoichiometric material rich in surface ions (carbonate, magnesium, citrate), which are readily replaced by fluoride ion, thus affording protection to the teeth.

brand name

Alveograf (Sterling Winthrop); Periograf (Sterling Winthrop).

General Description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.

Flammability and Explosibility

Not classified

Pharmaceutical Applications

Modified hydroxylapatite, also frequently called hydroxyapatite and better known as bone mineral, makes up ～50% of our bones. Hydroxylapatite is a natural form of the mineral calcium apatite, whose formula is usually denoted as Ca₁₀(PO₄)₆(OH)₂. Modifications of hydroxylapatite can also be found in the teeth, and a chemically identical substance is often used as filler for replacement of bones, and so on. Nevertheless, despite similar or identical chemical compositions, the response of the body to these compounds can be quite different.

Hydroxyapatite Preparation Products And Raw materials

Raw materials

Preparation Products

L-Tyrosine Calcium phosphate monobasic Gelatin

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View Lastest Price from Hydroxyapatite manufacturers

Hebei Dangtong Import and export Co LTD

Product: Hydroxyapatite 1306-06-5
Price: US $70.00-60.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20Tons
Release date: 2023-10-09

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Hydroxylapatite 1306-06-5
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99.7%
Supply Ability: 200000kg
Release date: 2024-04-26

Shaanxi Haibo Biotechnology Co., Ltd

Product: Hydroxyapatite 1306-06-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-12-05

1306-06-5, HydroxyapatiteRelated Search:

Tylosin phosphate Ammonium hydroxide Calcium hydroxide Sodium hydroxide Zinc phosphate Triethyl phosphate Trisodium phosphate Potassium di-tert-butyl phosphate Manganous dihydrogen phosphate Dibenzyl phosphate Tri-o-cresyl Phosphate Diphenyl phosphate DIETHYL PHOSPHATE Triisobutyl phosphate Triphenyl phosphate phosphate HYDROXYAPATITE TYPE I CALCIUM HYDROXYAPATITE,HYDROXYAPATITE,CALCIUM PHOSPHATE TRIBASIC,HYDROXYLAPATITE,HYDROXYLAPATITE CERAMIC Tricalcium Phosphate

CALCIUM PHOSPHATE, HYDROXIDE PURIFIED

Hydroxyapatite: (Calcium hydroxyapatite)

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

CALCIUM PHOSPHATE, HYDROXIDE REAGENT

Apatite HAP

Hydroxyapatite,Calcium hydroxyphosphate, Calcium phosphate tribasic, HAp, Hydroxylapatite

Hydroxylapatite, for analysis 25GR

apatite,hydroxy

Bonedust

calciumorthophosphate,basic

hydroxylapatite(ca5(oh)(po4)3)

hydroxylapatite(ca5(oh)(po4)3)(9ci)

hydroxylapatite[ca5(oh)(po4)3]

monite

Food Grade Hydroxyapatite, HAP

Medical Grade Hydroxyapatite, HAP

Hydroxya

Hydroxylapatite, 99%, Globular, 80 μm

Hydroxylapatite,globular(HCa5O5P)

Hydroxylapatite,needle-like(HCa5O5P)

Hydroxylapatite,short rod-like(HCa5O5P)

hydroxylapatite high resolution

Hydroxylapatite, 97.5%, Needle-like, 20 nm

Hydroxylapatite, 99%, Fiber-like, Width: 10 nm

Hydroxylapatite, 99%, Needle-like, 20 nm

Hydroxylapatite, 99%, Rod-like, Width:30 nm

pentacalciummonohydroxyorthophosphate

periograf

supertite10

Hyaluronic Acid, HA

Hydroxylapatit

HYDROXYLAPATITE REAGENT GRADE POWDER

Hydroxylapatite, for analysis

Tribasic calcium phosphate, NF, Fine GranularTribasic calcium phosphate, NF, Fine GranularTribasic calcium phosphate, NF, Fine GranularTribasic calcium phosphate, NF, Fine Granular

CALCIUM PHOSPHATE, HYDROXIDE, REAGENTCALCIUM PHOSPHATE, HYDROXIDE, REAGENTCALCIUM PHOSPHATE, HYDROXIDE, REAGENTCALCIUM PHOSPHATE, HYDROXIDE, REAGENT

CALCIUM PHOSPHATE HYDROXIDE

CALCIUM HYDROXIDE PHOSPHATE

CALCIUM HYDROXYAPATITE

BONE ASH

BEEF BONE POWDER

APATITE HAP, MONOCLINIC

HA, BOVINE

HYALURONIC ACID HUMAN

HYALURONIC ACID, BOVINE

HYDROXYLAPATITE

HYDROXYLAPATITE CERAMIC

HYDROXYAPATITE

DURAPATITE

COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4]

Select-HA? Hyaluronan

Hydroxyapatite Microspheres

Hydroxyapatite powder, 10 mum, >=100 m2/g

Hydroxyapatite powder, 5 mum, surface area >=100 m2/g

HAw

ALTERNATING COPOLY: BETA-GLUCURONIC ACID - [1->5] - BETA - N - ACETYL GLUCOSAMINE - [1->4]

TRICALCIUM PHOSPHATE

TRIBASIC CALCIUM PHOSPHATE