Benidipine
- Product Name
- Benidipine
- CAS No.
- 105979-17-7
- Chemical Name
- Benidipine
- Synonyms
- BENIDIPINE HCL;(R*,R*)-(±)-(3,5-Pyridinedicarboxylic acid 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-methyl 1- (phenylmethyl)-3-piperidinyl ester monohydrochloride;KW-3049;5-O-[(3R)-1-benzylpiperidin-3-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl5-[(3R)-1-(phenylMethyl)-3-piperidinyl] ester, (4R)-rel-;CONIEL;BENIDIPINE;NACADIPINE;CAPADIPINE;rac Benidipine
- CBNumber
- CB2131201
- Molecular Formula
- C28H31N3O6
- Formula Weight
- 505.56
- MOL File
- 105979-17-7.mol
Benidipine Property
- Boiling point:
- 625.2±55.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- pka
- pKa 7.34(H2O(long extrapolation) ) (Uncertain)
- Water Solubility
- 316μg/L at 25℃
- LogP
- 4.61
- CAS DataBase Reference
- 105979-17-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B157508
- Product name
- racBenidipine
- Packaging
- 0.5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- API0002106
- Product name
- CONIEL
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $693
- Updated
- 2021/12/16
- Product number
- 18512
- Product name
- Benidipine
- Packaging
- 25mg
- Price
- $1500
- Updated
- 2021/12/16
- Product number
- API0002106
- Product name
- CONIEL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1501.5
- Updated
- 2021/12/16
- Product number
- 3003B
- Product name
- Benidipine
- Packaging
- 100mg
- Price
- $89
- Updated
- 2021/12/16
Benidipine Chemical Properties,Usage,Production
Uses
Benidipine (CAS# 105979-17-7) is a 1,4-dihydropyridine and a calcium channel antagonist. Antihypertensive.
Enzyme inhibitor
This oral, once-daily antihypertensive agent (FW = 505.57 g/mol; CAS 105979-17-7), also known by its code name KW-3049, trade name Coniel?, and systematic name O -methyl,O -[(3R)-1-(phenylmethyl)piperidin-3-yl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, is a dihydropyridine-class calcium ion blocker that is effective against L-, N-, and T-channels, with potent and selective inhibitory action on cardiac slow calcium channels. Benidipine bound stereospecifically to nitrendipine binding sites of rat myocardium with high affinity (Ki = 0.13 nM) and to the rat brain a1-adrenergic receptor (Ki = 1.2 μM). KW-3049 exhibited no remarkable binding affinity to a2 adrenergic, b-adrenergic, D2 dopamine, H1 histamine, S2 serotonin, A1 adenosine, A2 adenosine and muscarinic cholinergic receptors at 100 μM.
Benidipine Preparation Products And Raw materials
Raw materials
Preparation Products
Benidipine Suppliers
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View Lastest Price from Benidipine manufacturers
- Product
- Benidipine 105979-17-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Benidipine 105979-17-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Benidipine 105979-17-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-11