ChemicalBook > CAS DataBase List > 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid

Product Name
4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid
CAS No.
152628-03-0
Chemical Name
4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid
Synonyms
4-METHYL-2-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID;2-N-PROPYL-4-METHYL-6-CARBOXY-BENZIMIDAZOLE;Single-imidazole;2-N-Propyl-4-Meth;Telmisartan Intermediate 3;BENZIMIDAZOLE CARBOXYLIC ACID;TelMisartan BenziMidazole Acid;Telmisartan Benzimidazole Acid Impurity;6-Carboxy-4-methyl-2-propylbenzimidazole;4-METHYL-2-PROPYL-6-CARBOXYL BENZIMIDAZOLE
CBNumber
CB2133083
Molecular Formula
C12H14N2O2
Formula Weight
218.25
MOL File
152628-03-0.mol
More
Less

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Property

Melting point:
300 °C
Boiling point:
491.8±25.0 °C(Predicted)
Density 
1.259±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
pka
3.19±0.30(Predicted)
form 
Powder
color 
Pale Yellow to Tan
InChIKey
XWAJTVCEILFDGU-UHFFFAOYSA-N
CAS DataBase Reference
152628-03-0(CAS DataBase Reference)
More
Less

Safety

HS Code 
29332900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
M2000
Product name
4-Methyl-2-propyl-6-benzimidazolecarboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$60
Updated
2025/07/31
Usbiological
Product number
B1062
Product name
1H-Benzimidazole-6-carboxylic-4-methyl-2-propyl
Packaging
1g
Price
$403
Updated
2021/12/16
TRC
Product number
B197825
Product name
1H-Benzimidazole-4-methyl-2-propyl-6-carboxylicAcid
Packaging
5g
Price
$440
Updated
2021/12/16
Chem-Impex
Product number
42588
Product name
4-Methyl-2-propyl-6-benzimidazolecarboxylicacid,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
5G
Price
$50.85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18198
Product name
1H-Benzimidazole-4-methyl-2-propyl-6-carboxylic acid
Packaging
1g
Price
$60
Updated
2021/12/16
More
Less

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Light Yellow to Tan Powder

Uses

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid is a useful synthetic intermediate,a useful compound in organic synthesis.

Synthesis

152628-01-8

152628-03-0

Example 4: Methyl 3-methyl-4-butyrylamino-5-nitrobenzoate (II) (10 g, 0.036 mol) was suspended in 60 ml of water and heated to 70-80 °C. A suspension of sodium dithionite (21.75 g, 0.124 mol) in 60 ml of water was added slowly and heated to 90-100 °C. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 10-11 and the temperature was maintained with continued stirring until TLC detection showed complete disappearance of methyl 3-methyl-4-butyrylamino-5-nitrobenzoate. Subsequently, the pH of the reaction mixture was adjusted to 6-6.5. The resulting solid was filtered and dried at 45-50 °C to afford 2-n-propyl-4-methyl-6-carboxybenzimidazole (7.5 g, yield: 96.4%).

References

[1] Patent: WO2012/28925, 2012, A2. Location in patent: Page/Page column 18
[2] Journal of Heterocyclic Chemistry, 2003, vol. 40, # 6, p. 1107 - 1112
[3] Journal of Medicinal Chemistry, 1993, vol. 36, # 25, p. 4040 - 4051
[4] Patent: WO2012/28925, 2012, A2
[5] Organic Process Research and Development, 2007, vol. 11, # 1, p. 81 - 85

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitrobenzoic acid Nickel Hydrazine hydrate Triethylamine Butyryl chloride Nitric acid Acetic acid Methanol Sulfuric acid

Preparation Products

More
Less

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Suppliers

Americas 1 Australia 1 Canada 3 China 275 Europe 3 Germany 5 India 54 Japan 4 Poland 1 South Korea 1 Spain 1 Switzerland 1 Ukraine 1 United Kingdom 12 United States 54 Global 417
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
QUALITY CONTROL CHEMICALS INC.
Tel
+86-66853366 +86-15920483169
Fax
(626) 453-0409
Email
orders@qccstandards.com
Country
United States
ProdList
26
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Alfa Chemistry
Tel
Email
info@alfa-chemistry.com
Country
United States
ProdList
2344
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Ambeed, Inc.
Tel
--
Fax
--
Email
info@ambeed.com
Country
United States
ProdList
502
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
vulcanchem
Tel
--
Fax
--
Email
info@vulcanchem.com
Country
United States
ProdList
268
Advantage
58
A Chemtek, Inc.
Tel
--
Fax
--
Email
sales@achemtek.com
Country
United States
ProdList
154
Advantage
58
eNovation Chemicals LLC
Tel
--
Fax
--
Email
ales@eNovationChem.com
Country
United States
ProdList
1673
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
AstaTech, Inc.
Tel
--
Fax
--
Email
sales@astatechinc.com
Country
United States
ProdList
904
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
2A Biotech USA
Tel
--
Fax
--
Email
info@2abiotech.com
Country
United States
ProdList
1785
Advantage
58
AA Blocks LLC
Tel
--
Fax
--
Email
s@aablocks.com
Country
United States
ProdList
536
Advantage
58
MuseChem (A division of Adv Biolabs, Inc.)
Tel
--
Fax
--
Email
@musechem.com
Country
United States
ProdList
246
Advantage
58
Synblock,Inc.
Tel
--
Fax
--
Email
sales@synblock.com
Country
United States
ProdList
228
Advantage
58
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
Aurum Pharmatech, LLC
Tel
--
Fax
--
Email
sales@aurumpharmatech.com
Country
United States
ProdList
498
Advantage
0
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
CHEM-IS-TRY, Inc.
Tel
--
Fax
--
Email
sales@chem-is-try.com
Country
United States
ProdList
551
Advantage
56
Aozeal Certified Standards (AOCS), Inc.
Tel
--
Fax
--
Email
info@aozeal.com
Country
United States
ProdList
504
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
AEchem Scientific Corporation
Tel
--
Fax
--
Email
info@aechemsc.com
Country
United States
ProdList
77
Advantage
0
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Molcan Corporation
Tel
--
Fax
--
Email
info@molcan.com
Country
United States
ProdList
686
Advantage
60
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Fragmenta
Tel
--
Fax
--
Email
sales@fragmenta.com
Country
United States
ProdList
1068
Advantage
0
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
More
Less

View Lastest Price from 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price
US $25.00/ASSAYS
Min. Order
100ASSAYS
Purity
99.5%
Supply Ability
100 mt
Release date
2024-11-19
Henan Aochuang Chemical Co.,Ltd.
Product
4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10
Shaanxi Haibo Biotechnology Co., Ltd
Product
4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-28

152628-03-0, 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acidRelated Search:

Propyl gallate Methyl salicylate N,N-Dimethylallylamine 3-Methyl-2-butanone Benzimidazole Cyclopropyl methyl ketone Isopropyl alcohol Propyl butyrate 2-Methylbenzimidazole Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate ALLYL METHYL ETHER Methyl 4'-bromomethyl biphenyl-2-carboxylate tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Thiophanate-methyl Methyl 2-METHYLPENTANE Methyl bromide 1H-Benzimidazole-5-carboxylic acid

  • 4-METHYL-2-N-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID
  • 4-METHYL-2-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID
  • 4-METHYL-2-PROPYL-6-CARBOXYL BENZIMIDAZOLE
  • 2-N-PROPYL-4-METHYL-6-CARBOXY-BENZIMIDAZOLE
  • 2-N-PROPYL-4-METHYLBENZIMIDAZOLE-6-CARBOXYLIC ACID
  • 2-PROPYL-4-METHYL-6-CARBOXYL BENZIMIDAZOLE
  • Telmisartan Intermediate 3
  • 2-N-Propyl-4-Meth
  • 6-Carboxy-4-methyl-2-propylbenzimidazole
  • 1H-Benzimidazole-4-methyl-2-propyl-6-carboxylic Acid
  • 4-Methyl-2-Propyl-1h-Benzimidazole-6-Carboxyboxylic Acid
  • 1H-BENZIMIDAZOLE-6-CARBOXYLIC-4-METHYL-2-PROPYL
  • 4-Methyl-2-Propyl-1H-Benzimidazole-6-CarboxylicAcid[TelmisartanIntermediates]
  • 2-N-Propyl-4-Methyl-6-Carbony-Benzimidazole
  • 2-PROPYL-4-METHYL-1H-BENZIMIDAZOLE-6-CARBOXYLICACID
  • 1H-Benzimidazole-5-carboxylic acid, 7-methyl-2-propyl,
  • 1H-Benzimidazol-5-carbonsure, 7-methyl-2-propyl-
  • 4-METHYL-2-PROPYL-6-BENZIMIDAZOLECARBOXYLIC ACID
  • 2-n-Propyl-4-Methyl-6-Carboxylate-1H-Benzimidazole
  • 7-methyl-2-propyl-3H-benzo[d]imidazole-5-carboxylic acid
  • 4-Methyl-2-propyl-1H-1,3-benzodiazole-6-carboxylic acid
  • 2-n-propyl-4-Methyl-6-carboxy-benziMidazole 3
  • 4-Methyl-2-propyl-1H-benzo[d]iMidazole-6-carboxylic acid
  • TelMisartan BenziMidazole Acid
  • 2-n-propyl-1H-benzimidazole-6-carboxylic acid
  • Single-imidazole
  • 7-methyl-2-propyl-3aH-benzimidazole-5-carboxylic acid
  • Telmisartan Benzimidazole Acid Impurity
  • 4-Methyl-2-propyl-6-benzimidazolecarboxylicAcid&gt
  • 2-propyl-4-methyl-benzimidazole-6-carboxylic acid
  • Telmisartan Benzimidazole AcidQ: What is Telmisartan Benzimidazole Acid Q: What is the CAS Number of Telmisartan Benzimidazole Acid Q: What is the storage condition of Telmisartan Benzimidazole Acid Q: What are the applications of Telmisartan Benzimidazole Acid
  • 4-Methyl-2-n-propyl-6-carboxylic benzimidazole
  • 4-Methyl-2-n-propyl-1H-benzimidazoIe-6-carbox
  • 4-Methyl-2-Propylbenzimidazole-6-Carboxylic Acid
  • BENZIMIDAZOLE CARBOXYLIC ACID
  • 7-methyl-2-propaneyl-(1H)-benzoimidazole-5-carboxylic acid
  • 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylicacid (BIM-I)
  • 2-Propyl-4-methyl-6-carboxylic benzimidazole
  • 7-Methyl-2-propyl-1H-benzo[d]imidazol-5-carboxylic acid
  • 152628-03-0
  • 1526280-03-0
  • Heterocycles
  • Imidazoles
  • Aromatics
  • INTERMEDIATESOF
  • Imidazol&Benzimidazole