ChemicalBook > CAS DataBase List > Propitocaine hydrochloride

Propitocaine hydrochloride

Product Name
Propitocaine hydrochloride
CAS No.
1786-81-8
Chemical Name
Propitocaine hydrochloride
Synonyms
xylonest;Prilocaine HC;PRILOCAINE HCL;Citanest Plain;Prilocaine HCI;Ropitocaine Hcl;Propitocaine HCL;l-67hydrochloride;prilocainechloride;citanesthydrochloride
CBNumber
CB2139212
Molecular Formula
C13H21ClN2O
Formula Weight
256.77
MOL File
1786-81-8.mol
More
Less

Propitocaine hydrochloride Property

Melting point:
168-170°C
storage temp. 
2-8°C
solubility 
Freely soluble in water and in ethanol (96 per cent), very slightly soluble in acetone
color 
White to Off-White
Merck 
14,7743
InChI
InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
InChIKey
BJPJNTKRKALCPP-UHFFFAOYSA-N
SMILES
C1(=CC=CC=C1C)NC(=O)C(C)NCCC.Cl
CAS DataBase Reference
1786-81-8(CAS DataBase Reference)
More
Less

Safety

WGK Germany 
3
RTECS 
UG5775000
HS Code 
29242990
Toxicity
man,LDLo,parenteral,12343ug/kg/1H (12.343mg/kg),BLOOD: HEMORRHAGE,Journal of Analytical Toxicology. Vol. 10, Pg. 75, 1986.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3106
Product name
Prilocaine Hydrochloride
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$182
Updated
2024/03/01
Sigma-Aldrich
Product number
BP497
Product name
Prilocaine hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$257
Updated
2024/03/01
Sigma-Aldrich
Product number
1561008
Product name
Prilocaine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Sigma-Aldrich
Product number
P3347
Product name
Prilocaine hydrochloride
Purity
meets USP testing specifications
Packaging
1g
Price
$99
Updated
2022/05/15
Sigma-Aldrich
Product number
BP497
Product name
Prilocaine hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Price
$220
Updated
2021/12/16
More
Less

Propitocaine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

antibacterial

Uses

Propitocaine hydrochloride is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.

Uses

Anesthetic (local).

Definition

ChEBI: The monohydrochloride salt of prilocaine.

brand name

Citanest (AstraZeneca).

Biological Functions

Prilocaine hydrochloride (Citanest) is an amide anesthetic whose onset of action is slightly longer than that of lidocaine; its duration of action is comparable. Prilocaine is 40% less toxic acutely than lidocaine, making it especially suitable for regional anesthetic techniques. It is metabolized by the liver to orthotoluidine, which when it accumulates, can cause conversion of hemoglobin (HB+++ to methemoglobin (HB+++. Oxygen transport is impaired in the presence of methemoglobinemia. Treatment involves the use of reducing agents, such as methylene blue, given intravenously, to reconvert methemoglobin to hemoglobin.

Contact allergens

Prilocaine in a local anesthetic of the amide group. It can induce allergic contact dermatitis, particularly from EMLA? cream.

Side effects

Common adverse reactions include bradycardia, hypotension, urticaria, edema, anaphylactoid reactions, lightheadedness, nervousness, euphoria, confusion, dizziness, drowsiness, tinnitus. The safety and effectiveness of prilocaine depend on proper dosage, correct technique, adequate precautions, and readiness for emergencies.

Propitocaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Propitocaine hydrochloride Suppliers

Canada 2 China 308 Europe 2 France 1 Germany 2 India 27 Japan 1 Russia 1 South Korea 1 Spain 1 Switzerland 2 United Kingdom 8 United States 29 USA 1 Global 386
Shandong Mingfeng Pharmaceutical and Technology Co. Ltd
Tel
-1345456643 15315114555
Fax
QQ:1345456643
Email
1345456643@qq.com
Country
China
ProdList
250
Advantage
58
CHENGHUI PHARMACEUTICAL GROUP LTD
Tel
0531-58897070 15254140813
Fax
0531-58897046
Email
market@jnchsd.com
Country
China
ProdList
209
Advantage
58
Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd.
Tel
0571-63280982
Email
sales@bx-biopharm.com
Country
China
ProdList
49
Advantage
58
Wuhan Yida Pharmaceutical Co., Ltd
Tel
+86-13401188533 +86-13476102740
Email
3451936732@qq.com
Country
China
ProdList
64
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4271
Advantage
65
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Jinan Chenghui Shuangda biological Co., LTD
Tel
0531-58897003 15550412551
Fax
0531-58897003
Email
market@jnchsd.com
Country
China
ProdList
209
Advantage
62
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4979
Advantage
50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Shenzhen Shijingu Technology Co., Ltd
Tel
(0086)755-61930359 (0086)18038192047
Fax
(0086)755-84556470
Email
jo@pharmade.com
Country
China
ProdList
279
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3123
Advantage
55
Vientiane Tianjin Hengyuan Technology Co., Ltd.
Tel
15722085254
Fax
022-26358246
Email
phytochemical@126.com
Country
China
ProdList
813
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Changzhou josenchem Pharmaceutical Chemical Material Co.,Ltd.
Tel
519-519-85286950 13338194135
Fax
0519-85286950
Email
info@josenchem.com
Country
China
ProdList
75
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd.
Tel
13720616393；029-84385017-8003 13720616393
Fax
029-84385017
Email
sales@pioneerbiotech.com
Country
China
ProdList
1065
Advantage
56
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4901
Advantage
55
Beri Pharma Co., Ltd.
Tel
0756-07568699456 13427714006
Fax
+86-756-8699456
Email
sales@zhberi.com
Country
China
ProdList
208
Advantage
58
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3066
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
Lancrix Chemicals
Tel
86-21-50817262
Fax
86-21-57712035
Email
sales@lancrix.com
Country
China
ProdList
1503
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
025-57798860
Email
sales@njromanme.com
Country
China
ProdList
4534
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13374
Advantage
58
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13810511747
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
Wuhan Magic Biological Technology Co., Ltd.
Tel
18872289958、027-52304252、3400508168
Fax
027-52304252
Email
3400508168@qq.com
Country
China
ProdList
1910
Advantage
55
More
Less

View Lastest Price from Propitocaine hydrochloride manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Propitocaine hydrochloride 1786-81-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-07-14
Shanghai Aosiris new Material Technology Co., LTD
Product
Propitocaine hydrochloride 1786-81-8
Price
US $3.00-1.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10 tons
Release date
2024-04-19
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
Prilocaine hydrochloride 1786-81-8
Price
US $1.00/mg
Min. Order
1000mg
Purity
99
Supply Ability
5ton/month
Release date
2022-05-26

1786-81-8, Propitocaine hydrochloride Related Search:

Buflomedil hydrochloride 2-Chlorotoluene 3-Chloropropylamine hydrochloride o-Xylene 2-Aminobenzotrifluoride Prilocaine Topotecan hydrochloride p-Toluenesulfonamide Cetirizine dihydrochloride PHTHALAMIDE 1-AdaMantanethylaMine Glycinamide hydrochloride Proparacaine hydrochloride Dapoxetine Diltiazem hydrochloride Sibutramine hydrochloride aptocaine Quatacaine

  • 2-(propylamino)-o-propionotoluidide hydrochloride
  • 2-(propylamino)-o-propionotoluididmonohydrochloride
  • alpha-propylamine-2-methyl-propionanilidehydrochloride
  • citanesthydrochloride
  • l-67hydrochloride
  • Prilocaine HCL //Prilocaine
  • N-(o-tolyl)-2-(propylamino)propionamide hydrochloride
  • Prilocaine hydrochloride,N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride
  • Prilocaine Hydrochloride (200 mg)
  • Prilocaine HC
  • N1-(2-methylphenyl)-N2-propylalaninamide hydrochloride
  • Ropitocaine Hcl
  • n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride
  • prilocainechloride
  • xylonest
  • PRILOCAINE HCL
  • PRILOCAINE HYDROCHLORIDE
  • propitocaine hydrochloride
  • N-(2-METHYLPHENYL)-2-(PROPYLAMINO)PROPANAMIDE HYDROCHLORIDE
  • Propitocaine HCL
  • 2-(propylaMino)-N-(o-tolyl)propanaMide hydrochloride
  • Prilocaine hydrochloride, >=99%
  • PRILOCAINE HYDROCHLORIDE USP
  • PRILOCAINE HYDROCHLORIDE ASSAY STANDARD BP(CRM STANDARD)
  • PRILOCAINE HYDROCHLORIDE BP STANDARD
  • PRILOCAINE HYDROCHLORIDE BP STANDARD(CRM STANDARD)
  • PRILOCAINE HYDROCHLORIDE EPP
  • PRILOCAINE HYDROCHLORIDE EPP(CRM STANDARD)
  • PRILOCAINE HYDROCHLORIDE MM
  • PRILOCAINE HYDROCHLORIDE MM(CRM STANDARD)
  • PrilocaineHydrochloroide
  • Propanamide, N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride
  • PRILOCAINI HVDROCHLORIDUM
  • a-(Propylamino)-2-methylpropionanilide hydrochloride
  • Citanest Plain
  • o-Propionotoluidide, 2-(propylamino)-, monohydrochloride (8CI)
  • Propanamide, N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride (9CI)
  • Prilocaine for peak identification
  • Prilocaine hydrochloride, 99%, a local anesthetic of the amino amide type
  • Ropitocaine hydrochloride
  • Prilocaine Hydrochloride &gt
  • Prilocaine Hydrochloride /Prilocaine HCL
  • Propanamide, N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1)
  • 2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride
  • Propitocaine hydrochloride USP/EP/BP
  • Prilocaine hydrochloride salt
  • Prilocaine hydrochloride, Pharma
  • prilocaine HCL powder
  • Prilocaine HydrochlorideQ: What is Prilocaine Hydrochloride Q: What is the CAS Number of Prilocaine Hydrochloride Q: What is the storage condition of Prilocaine Hydrochloride Q: What are the applications of Prilocaine Hydrochloride
  • Prilocaine Hydrochloride (1561008)
  • Prilocaine HCI
  • Prilocaine HCl IP/USP/BP/EP
  • Prilocaine Hydrochloride, ≥ 98.0%
  • 1786-81-8
  • C13H20N2OHCl
  • C13H21ClN2O
  • Used for local nerve block and for spinal anesthesia; pharmacological properties are similar to those of lidocaine.
  • Sodium channel