Propitocaine hydrochloride
- Product Name
- Propitocaine hydrochloride
- CAS No.
- 1786-81-8
- Chemical Name
- Propitocaine hydrochloride
- Synonyms
- xylonest;Prilocaine HC;PRILOCAINE HCL;Citanest Plain;Prilocaine HCI;Ropitocaine Hcl;Propitocaine HCL;l-67hydrochloride;prilocainechloride;citanesthydrochloride
- CBNumber
- CB2139212
- Molecular Formula
- C13H21ClN2O
- Formula Weight
- 256.77
- MOL File
- 1786-81-8.mol
Propitocaine hydrochloride Property
- Melting point:
- 168-170°C
- storage temp.
- 2-8°C
- solubility
- Freely soluble in water and in ethanol (96 per cent), very slightly soluble in acetone
- color
- White to Off-White
- Merck
- 14,7743
- InChI
- InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
- InChIKey
- BJPJNTKRKALCPP-UHFFFAOYSA-N
- SMILES
- C1(=CC=CC=C1C)NC(=O)C(C)NCCC.Cl
- CAS DataBase Reference
- 1786-81-8(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- RTECS
- UG5775000
- HS Code
- 29242990
- Toxicity
- man,LDLo,parenteral,12343ug/kg/1H (12.343mg/kg),BLOOD: HEMORRHAGE,Journal of Analytical Toxicology. Vol. 10, Pg. 75, 1986.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHR3106
- Product name
- Prilocaine Hydrochloride
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 500MG
- Price
- $182
- Updated
- 2024/03/01
- Product number
- BP497
- Product name
- Prilocaine hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $257
- Updated
- 2024/03/01
- Product number
- 1561008
- Product name
- Prilocaine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- P3347
- Product name
- Prilocaine hydrochloride
- Purity
- meets USP testing specifications
- Packaging
- 1g
- Price
- $99
- Updated
- 2022/05/15
- Product number
- BP497
- Product name
- Prilocaine hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Price
- $220
- Updated
- 2021/12/16
Propitocaine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
antibacterial
Uses
Propitocaine hydrochloride is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.
Uses
Anesthetic (local).
Definition
ChEBI: The monohydrochloride salt of prilocaine.
brand name
Citanest (AstraZeneca).
Biological Functions
Prilocaine hydrochloride (Citanest) is an amide anesthetic whose onset of action is slightly longer than that of lidocaine; its duration of action is comparable. Prilocaine is 40% less toxic acutely than lidocaine, making it especially suitable for regional anesthetic techniques. It is metabolized by the liver to orthotoluidine, which when it accumulates, can cause conversion of hemoglobin (HB+++ to methemoglobin (HB+++. Oxygen transport is impaired in the presence of methemoglobinemia. Treatment involves the use of reducing agents, such as methylene blue, given intravenously, to reconvert methemoglobin to hemoglobin.
Contact allergens
Prilocaine in a local anesthetic of the amide group. It can induce allergic contact dermatitis, particularly from EMLA? cream.
Side effects
Common adverse reactions include bradycardia, hypotension, urticaria, edema, anaphylactoid reactions, lightheadedness, nervousness, euphoria, confusion, dizziness, drowsiness, tinnitus. The safety and effectiveness of prilocaine depend on proper dosage, correct technique, adequate precautions, and readiness for emergencies.
Propitocaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Propitocaine hydrochloride Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
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- Fax
- --
- info@biotrend.ch
- Country
- Germany
- ProdList
- 1250
- Advantage
- 62
View Lastest Price from Propitocaine hydrochloride manufacturers
- Product
- Propitocaine hydrochloride 1786-81-8
- Price
- US $2.00/kg
- Min. Order
- 0.10000000kg
- Purity
- 99%
- Supply Ability
- 200KG
- Release date
- 2024-07-23
- Product
- Prilocaine hydrochloride 1786-81-8
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000
- Release date
- 2023-04-06
- Product
- Prilocaine hydrochloride 1786-81-8
- Price
- US $50.00-100.00/G
- Min. Order
- 10G
- Purity
- 98%
- Supply Ability
- 2000KG
- Release date
- 2024-06-06