4-amino-2-methylbenzonitrile
- Product Name
- 4-amino-2-methylbenzonitrile
- CAS No.
- 72115-06-1
- Chemical Name
- 4-amino-2-methylbenzonitrile
- Synonyms
- 4-amino-2-methylbenzonitrile;2-methyl-4-aminobenzonitrile;Benzonitrile, 4-amino-2-methyl-
- CBNumber
- CB21482164
- Molecular Formula
- C8H8N2
- Formula Weight
- 132.16
- MOL File
- 72115-06-1.mol
4-amino-2-methylbenzonitrile Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- Appearance
- Brown to black Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS015445
- Product name
- 4-amino-2-methylbenzonitrile
- Purity
- AldrichCPR
- Packaging
- 100MG
- Price
- $99.7
- Updated
- 2023/06/20
- Product number
- A898578
- Product name
- 4-Amino-2-methylbenzonitrile
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CHM0033549
- Product name
- 4-AMINO-2-METHYLBENZONITRILE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $6063.75
- Updated
- 2021/12/16
- Product number
- FA140022
- Product name
- 4-Amino-2-methylbenzonitrile
- Packaging
- 1g
- Price
- $111
- Updated
- 2021/12/16
- Product number
- Z5070
- Product name
- 4-Amino-2-methylbenzonitrile
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
4-amino-2-methylbenzonitrile Chemical Properties,Usage,Production
Synthesis
89001-53-6
72115-06-1
(b) Synthesis of 4-amino-2-methylbenzonitrile: Tin chloride dihydrate (18.5 g, 82.0 mmol) was added to a solution of 2-methyl-4-nitrobenzonitrile (3.80 g, 23.4 mmol) in ethanol (140 mL). The reaction mixture was stirred under reflux conditions for 3 hours. After completion of the reaction, the solvent was removed by distillation. The residue was diluted with ethyl acetate and washed with saturated aqueous sodium bicarbonate solution. The precipitate produced during washing was removed by filtration through diatomaceous earth. The filtrate was extracted with ethyl acetate and the combined organic phases were dried with anhydrous magnesium sulfate, filtered and concentrated to give 4-amino-2-methylbenzonitrile (2.89 g, 94% yield).
References
[1] Patent: EP1500643, 2005, A1. Location in patent: Page 32
[2] Chemische Berichte, 1919, vol. 52, p. 1083
[3] Journal of Organic Chemistry, 1962, vol. 27, p. 1426 - 1430
[4] Journal of Medicinal Chemistry, 2001, vol. 44, # 23, p. 3856 - 3871
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 6, p. 1926 - 1930
4-amino-2-methylbenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4-amino-2-methylbenzonitrile Suppliers
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- Country
- The Netherlands
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