4-Amino-2-(trifluoromethyl)benzonitrile

Product Name: 4-Amino-2-(trifluoromethyl)benzonitrile
CAS No.: 654-70-6
Chemical Name: 4-Amino-2-(trifluoromethyl)benzonitrile
Synonyms: 4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE;5-AMINO-2-CYANOBENZOTRIFLUORIDE;4-Amino-2-(trifL;BUTTPARK 22\01-63;4-Amino-2-(trifluoro;Bicalutamide-EP-Imp-D;BicalutaMide EP IMpurity D;Bicalutamide intermediate F;4-Amino-2-(Trifluoromethyl)Ben;4-AMino-2-(trifluoroMethyl)...
CBNumber: CB9296914
Molecular Formula: C8H5F3N2
Formula Weight: 186.13
MOL File: 654-70-6.mol

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4-Amino-2-(trifluoromethyl)benzonitrile Property

Melting point:: 141-145 °C(lit.)
Boiling point:: 294.5±40.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Powder
pka: 0.50±0.10(Predicted)
color: White to off-white
BRN: 3278074
InChI: InChI=1S/C8H5F3N2/c9-8(10,11)7-3-6(13)2-1-5(7)4-12/h1-3H,13H2
InChIKey: PMDYLCUKSLBUHO-UHFFFAOYSA-N
SMILES: C(#N)C1=CC=C(N)C=C1C(F)(F)F
CAS DataBase Reference: 654-70-6(CAS DataBase Reference)
NIST Chemistry Reference: 5-Amino-2-cyanobenzotrifluoride(654-70-6)

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Safety

Hazard Codes: Xn,T
Risk Statements: 22-43-36/37/38-20/21/22
Safety Statements: 36-45-37/39-26
RIDADR: 3439
WGK Germany: 3
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: III
HS Code: 29049090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 631752
Product name: 4-Amino-2-(trifluoromethyl)benzonitrile
Purity: 97%
Packaging: 1g
Price: $25.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: BP1116
Product name: Bicalutamide impurity D
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 10MG
Price: $222
Updated: 2025/07/31

Sigma-Aldrich

Product number: 631752
Product name: 4-Amino-2-(trifluoromethyl)benzonitrile
Purity: 97%
Packaging: 5g
Price: $86.1
Updated: 2025/07/31

TCI Chemical

Product number: A1213
Product name: 5-Amino-2-cyanobenzotrifluoride
Purity: >98.0%(GC)
Packaging: 1g
Price: $28
Updated: 2025/07/31

TCI Chemical

Product number: A1213
Product name: 5-Amino-2-cyanobenzotrifluoride
Purity: >98.0%(GC)
Packaging: 5g
Price: $68
Updated: 2025/07/31

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4-Amino-2-(trifluoromethyl)benzonitrile Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-Amino-2-(trifluoromethyl)benzonitrile can serve as starting material in the synthesis of benzimidazoles, which can act as potential candidates in the treatment of breast cancer due to their ability to inhibit the growth of endothelial cells.

Uses

4-Amino-2-(trifluoromethyl)benzonitrile is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.

4-Amino-2-(trifluoromethyl)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-2-(trifluoromethyl)benzonitrile Suppliers

Americas 1 Belgium 1 Canada 2 China 472 Europe 3 France 2 Germany 6 India 25 Italy 1 Japan 2 Jordan 1 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 22 United States 53 Global 594

Jiangxi Jinfeng Pharmaceutical Co., Ltd

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
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View Lastest Price from 4-Amino-2-(trifluoromethyl)benzonitrile manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: 4-Amino-2-(trifluoromethyl)benzonitrile 654-70-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-29

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Amino-2-(trifluoromethyl)benzonitrile 654-70-6
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99.5%min HPLC
Supply Ability: 10 TONS
Release date: 2021-07-13

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Amino-2-(trifluoromethyl)benzonitrile 654-70-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

654-70-6, 4-Amino-2-(trifluoromethyl)benzonitrileRelated Search:

N,N-Dimethyl-1,4-phenylenediamine ALTRENOGEST Trifluoromethanesulfonic anhydride Benzonitrile p-Tolunitrile 3-(Trifluoromethyl)benzaldehyde (Trifluoromethyl)trimethylsilane Glycine 3-（trifluoromethyl) Cinnamaldehyde Tris(hydroxymethyl)aminomethane N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide Bicalutamide Desfluoro Bicalutamide Bicalutamide EP Impurity K BICALUTAMIDE-D4 Deshydroxy Bicalutamide

5-AMINO-2-CYANOBENZOTRIFLUORIDE

BUTTPARK 22\01-63

2-CYANO-5-AMINOBENZOTRIFLUORIDE

4-CYANO-3-TRIFLUOROMETHYLANILINE

4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE

5-AMINO-2-CYANO BENZOTRIFLUORID

4-Amino-2-(trifluoromethyl)benzontrile

4-Bromo-2-TrifluoromethylAniline/4-Bromo-2-(Trifluoromethyl)Aniline/2-Amino-5-Bromobenzotrifluoride

4-Amino-2-trifluoromethylbenzotrile

Bicalutamide intermediate F

4-Amino-2-(Trifluoromethyl)Ben

4-AMINO-2-(TRIFIUOROMETHYL) BENZ-IMIDAZOLE

5-Amino-2-cyanobenzotrifluoride98%

2-CYANO-5-AMINOBENZOTRIFLUORIDE(2-TRIFLUOROMETHYL-4-AMINOBENZONITRILE)

Bicalutamide Impurity 6(EP Impurity D)

4-aMino -2-(three fluoroMethyl)benzonitrile

Benzonitrile,4-aMino-2-(trifluoroMethyl)-

AMino - 4-2-3 Methyl phenyl nitrile

4-Amino-2-(trifL

Bicalutamide-EP-Imp-D

2-Cyano-5-aminobenzenetrifluoride

3-Amino-6-cyanobenzotrifluoride

4-Amino-2-(trifluoromethyl)benzenecarbonitrile

4-Amino-2-trifluoromethylbenzenecarbonitrile

4-AMino-2-(trifluoroMethyl)...

4-Cyano-3-Trifluoromethylanili

2-Cyano-5-amino benzotrifluoride ,99%

4-Amino-2-(trifluoro

4-AMino-α,α,α-trifluoro-o-tolunitrile

4-Amino-2-trifluoromethylbenzonitrile 4-Cyano-3-trifluoromethylaniline

4-Amino-2-(trifluoromethyl)benzonitrile 98%

BicalutaMide EP IMpurity D

5-Amino-2-cyanobenzotrifluoride, 4-Cyano-3-(trifluoromethyl)aniline

5-Amino-2-cyanobenzotrifluoride &gt

Bicalutamide Impurity 6(Bicalutamide EP Impurity D)

4-Cyano-3-trifluromethyllaniline

654-70-6

654-70-7

NCC6H3CF3NH2

Cyanides/Nitriles

Nitrogen Compounds

Organic Building Blocks

C8 to C9

Building Blocks

Building Blocks for Liquid Crystals

Benzonitriles (Building Blocks for Liquid Crystals)

Amines

Aromatics

Phenyls & Phenyl-Het

Chemical intermediate for Bicalutamide

Aromatic Nitriles

Aromatic Halides (substituted)

Phenyls & Phenyl-Het

Aniline

Bicalutamide

Chemical Amines

Benzonitriles (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals