3''-METHOXYOROBOL
- Product Name
- 3''-METHOXYOROBOL
- CAS No.
- 36190-95-1
- Chemical Name
- 3''-METHOXYOROBOL
- Synonyms
- -O-Methylorobol;3'-O-Methylorobol;3'-Methoxy-4',5,7-trihydroxyisoflavone;5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-
- CBNumber
- CB21484744
- Molecular Formula
- C16H12O6
- Formula Weight
- 300.26
- MOL File
- 36190-95-1.mol
N-Bromosuccinimide Price
- Product number
- M269675
- Product name
- 3''-Methoxy-4'',5,7-trihydroxyisoflavone
- Packaging
- 10mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- FO65483
- Product name
- Orobol-3'-methyl ether
- Packaging
- 5mg
- Price
- $61
- Updated
- 2021/12/16
- Product number
- FO65483
- Product name
- Orobol-3'-methyl ether
- Packaging
- 10mg
- Price
- $97.5
- Updated
- 2021/12/16
- Product number
- W1722
- Product name
- 3'-O-Methylorobol
- Packaging
- 10mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- FO65483
- Product name
- Orobol-3'-methyl ether
- Packaging
- 25mg
- Price
- $195
- Updated
- 2021/12/16
3''-METHOXYOROBOL Chemical Properties,Usage,Production
Uses
3''-Methoxy-4'',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2.
Definition
ChEBI: 3'-O-methylorobol is a hydroxyisoflavone that is orobol in which the hydroxy group at position 3' has been replaced by a methoxy group. It has been isolated from Crotalaria lachnophora. It has a role as a plant metabolite. It is a methoxyisoflavone and a hydroxyisoflavone. It is functionally related to an orobol.
3''-METHOXYOROBOL Preparation Products And Raw materials
Raw materials
Preparation Products
3''-METHOXYOROBOL Suppliers
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