Cyclosporin C

Product Name: Cyclosporin C
CAS No.: 59787-61-0
Chemical Name: Cyclosporin C
Synonyms: CL246;CS-2546;CS-2545;WF-3484;CYCLOSPORIN C;Thr2-cyclosporine;Cyclosporin C, >=95%;Cyclosporine IMpurity-C;Cyclosporin Impurity C;Cyclosporine Impurity 3
CBNumber: CB2153074
Molecular Formula: C62H111N11O13
Formula Weight: 1218.61
MOL File: 59787-61-0.mol

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Cyclosporin C Property

Melting point:: 144-1460C
alpha: D20 -255° (c = 0.5 in chloroform); D20 -182° (c = 0.5 in methanol)
Boiling point:: 1316.0±65.0 °C(Predicted)
Density: 1.033±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: ≥10mg/mL
pka: 13.06±0.70(Predicted)
form: Colorless to off-white crystalline solid.
color: White to Off-White
InChIKey: JTOKYIBTLUQVQV-PCACHRFWSA-N
CAS DataBase Reference: 59787-61-0

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29152
Product name: Cyclosporin C
Packaging: 5mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 29152
Product name: Cyclosporin C
Packaging: 25mg
Price: $330
Updated: 2024/03/01

Cayman Chemical

Product number: 29152
Product name: Cyclosporin C
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 29152
Product name: Cyclosporin C
Packaging: 10mg
Price: $183
Updated: 2024/03/01

TRC

Product number: C988905
Product name: Cyclosporin C
Packaging: 5mg
Price: $265
Updated: 2021/12/16

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Cyclosporin C Chemical Properties,Usage,Production

Description

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 μg/ml). Cyclosporin C (15 μg/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%. It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; ), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml. Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.

Chemical Properties

White Solid

Uses

A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cyclosporin C is a minor analogue of the cyclosporin complex produced by a number of fungal species, including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin C possesses immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A.

storage

+4°C

Cyclosporin C Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclosporin A

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Cyclosporin C Suppliers

Canada 1 China 157 Germany 1 India 5 South Korea 1 United Kingdom 7 United States 30 Global 202

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

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View Lastest Price from Cyclosporin C manufacturers

Jiangsu Nata Opto-electronic Material Co.,Ltd.

Product: Cyclosporin C 59787-61-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 95%
Supply Ability: 1kg
Release date: 2023-05-25

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Thr2-Cyclosporine 59787-61-0
Price: US $299.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1 ton
Release date: 2021-12-20

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Thr2-Cyclosporine
Price: US $16.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2kgs
Release date: 2021-12-30

59787-61-0, Cyclosporin CRelated Search:

Methyl acrylate (R)-(-)-2-Amino-3-methyl-1-butanol Dimethyl sulfone Bensulfuron methyl VALINOMYCIN CYCLOSPORIN D CYCLOSPORIN H Cyclosporin A Phenylmethylsulfonyl fluoride Thiophanate-methyl Hexamethylphosphoramide Kresoxim-methyl STAUROSPORINE Methylparaben METHYL THIOPHENE-2-CARBOXYLATE Methyl Methyl bromide Parathion-methyl

CYCLOSPORIN C

Cyclosporine C/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]

30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriaconta

CS-2545

CS-2546

cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal]

Cyclosporine EP Impurity C

Thr2-cyclosporine

Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]

(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Thr-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)

WF-3484

7-L-Threoninecyclosporin A

Cyclosporine IMpurity-C

7-L-Threoninecyclosporin A, WF 3484

7-Threonine-cyclosporin A

Cyclosporin C, >=95%

CL246

Cyclosporin Impurity C

Cyclosporin Impurity 3(Cyclosporin C)

Cyclosporin A, 7-L-threonine-

Cyclosporine Impurity 3

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-Hydroxy-2-methylhex-4-en-1-yl)-30-((R)-1-hydroxyethyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

(3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,1

(3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Cyclosporin C, EvoPure?

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-30-[(1R)-1-hydroxyethyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

59787-61-0

69787-61-0

59767-61-0

C62H111N11O13

Intermediates & Fine Chemicals

Peptides

Pharmaceuticals

ACTIVE PHARMACEUTICAL INGREDIENTS