ChemicalBook > CAS DataBase List > 4,4'-Difluorobenzhydrylpiperazine

4,4'-Difluorobenzhydrylpiperazine

Product Name
4,4'-Difluorobenzhydrylpiperazine
CAS No.
27469-60-9
Chemical Name
4,4'-Difluorobenzhydrylpiperazine
Synonyms
1-Bis(4-fL;TIMTEC-BB SBB002996;Flunarizine Impurity A;Flunarizine EP Impurity A;1-[Bis(4-Fluorophenyl)methyl]p;4,4-DIFLUOROBENZHYDRYLPIPERAZINE;4,4-Difluorobenzhydrolpiperazine;4,4'-Difluorobenzhydrylpiperazine;4,4'-DIFLUOROBENZHYDRYL PIPERAZINE;1-[Bis(4-fluorophenyl)methyl]pipera
CBNumber
CB2161725
Molecular Formula
C17H18F2N2
Formula Weight
288.33
MOL File
27469-60-9.mol
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4,4'-Difluorobenzhydrylpiperazine Property

Melting point:
88-92 °C(lit.)
Boiling point:
130 °C
Density 
1.1462 (estimate)
vapor pressure 
0.001-0.003Pa at 20-25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol,Toluene
pka
9.00±0.10(Predicted)
form 
Crystalline Powder
color 
White to yellow
Water Solubility 
0.34 g/L (20 ºC)
BRN 
620754
Stability:
Hygroscopic
LogP
3.3-3.5 at pH7-11
CAS DataBase Reference
27469-60-9(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25-36/37/38
Safety Statements 
26-45-36/37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
F 
10-34
Hazard Note 
Toxic
HazardClass 
IRRITANT
HazardClass 
6.1
PackingGroup 
III
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
552402
Product name
1-Bis(4-fluorophenyl)methyl piperazine
Purity
97%
Packaging
5g
Price
$138
Updated
2023/06/20
TCI Chemical
Product number
B2764
Product name
1-Bis(4-fluorophenyl)methyl piperazine
Purity
>97.0%(GC)
Packaging
5g
Price
$63
Updated
2024/03/01
TCI Chemical
Product number
B2764
Product name
1-Bis(4-fluorophenyl)methyl piperazine
Purity
>97.0%(GC)
Packaging
25g
Price
$213
Updated
2024/03/01
Alfa Aesar
Product number
H55173
Product name
1-[Bis(4-fluorophenyl)methyl]piperazine, 97%
Packaging
1g
Price
$16.6
Updated
2021/12/16
Alfa Aesar
Product number
H55173
Product name
1-[Bis(4-fluorophenyl)methyl]piperazine, 97%
Packaging
5g
Price
$59.8
Updated
2021/12/16
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4,4'-Difluorobenzhydrylpiperazine Chemical Properties,Usage,Production

Chemical Properties

white to yellow crystalline powder

Uses

1-Bis(4-fluorophenyl)methyl piperazine may be used to synthesize 1-[bis(4-fluorophenyl)methyl]-4-[3-[(N-ethoxycarbonyl-N-phenyl)amino]-2-hydroxypropyl]piperazine and (R, S) 3-[4-(bis(4-fluorophenyl)methyl)piperazin-1-yl]dihydrofuran-2(3H)-one.

General Description

1-Bis(4-fluorophenyl)methyl piperazine is formed during the synthesis of flunarizine. Its crystals exhibits monoclinic crystal system and space group P21/c.

4,4'-Difluorobenzhydrylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-Difluorobenzhydrylpiperazine Suppliers

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View Lastest Price from 4,4'-Difluorobenzhydrylpiperazine manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4,4'-Difluorobenzhydrylpiperazine 27469-60-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-07
Career Henan Chemical Co
Product
4,4'-Difluorobenzhydrylpiperazine 27469-60-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-02

27469-60-9, 4,4'-DifluorobenzhydrylpiperazineRelated Search:

3,4-Difluorobenzoic acid 1-Methylpiperazine 1,3-Difluorobenzene Florfenicol 2,4-Difluorobenzoic acid 1,2-Difluorobenzene Piperazine Almitrine dimesylate Lomerizine hydrochloride ALMITRINE Lomerizine Carsatrin Flunarizine dihydrochloride Flunarizine Efletirizine 1-BENZHYDRYLPIPERAZINE 4-{4-[Bis(4-fluorophenyl)methyl]piperazinyl}benzyl alcohol 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(4-NITROPHENYL)PIPERAZINE

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  • 1-(4,4'-DIFLUORODIPHENYLMETHYL)PIPERAZINE
  • 4,4'-DIFLUOROBENZHYDRYL PIPERAZINE
  • 4,4-DIFLUOROBENZHYDRYLPIPERAZINE
  • 4,4-Difluorobenzhydrolpiperazine
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  • 1-(4,4'-Difluorobenzhydryl)piperazine 97%
  • 1-[BIS(4-FLUOROPHENZYL)METHYL]PIPERAZINE
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  • N-MONO-(4,4''-DIFLUOROFLUOROBENZHYDRYL)PIPERAZINEFLUNARIZINE
  • Piperazine, 1-[bis(4-fluorophenyl)methyl]-
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  • 1-[bis(4-fluorophenyl)methyl]piperazine (OR) 4,4'-Difluorobenzhydrylpiperazine.
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  • 1-Bis(4-fL
  • Flunarizine EP Impurity AQ: What is Flunarizine EP Impurity A Q: What is the CAS Number of Flunarizine EP Impurity A Q: What is the storage condition of Flunarizine EP Impurity A Q: What are the applications of Flunarizine EP Impurity A
  • TIANFU CHEM 4,4'-Difluorobenzhydrylpiperazine
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  • 4,4'-Difluorobenzhydrylpiperazine
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  • 1-[bis(4-fluorophenyl)methyl]piperazine (OR) 4,4'-Difluorobenzhydrylpiperazine
  • 27469-60-9
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  • 27569-60-9
  • C17H18F2N2
  • C17H19ClF2N2
  • C17H18N2F2
  • C17H18F2H2
  • Heterocyclic Building Blocks
  • Piperazines
  • Building Blocks
  • Building Blocks
  • C16 to C29