(R)-Glycidyl butyrate
- Product Name
- (R)-Glycidyl butyrate
- CAS No.
- 60456-26-0
- Chemical Name
- (R)-Glycidyl butyrate
- Synonyms
- (R)-Oxiran-2-ylMethyl butyrate;OXIRAN-2-YLMETHYL BUTYRATE;(R)-(-)-GLYCIDYL BUTYRATE;Torezolid-18;(R)-Glycidyl butyrat;R-glycicyl butanoate;Tedizolid Impurity 44;(R)-GLYCIDYL BUTYRATE;Tedizolid Impurity 61;Tedizolidted Impurity 2
- CBNumber
- CB2164281
- Molecular Formula
- C7H12O3
- Formula Weight
- 144.17
- MOL File
- 60456-26-0.mol
(R)-Glycidyl butyrate Property
- alpha
- -30 º (c=neat)
- Boiling point:
- 197 °C(lit.)
- Density
- 1.032 g/mL at 20 °C(lit.)
- refractive index
- n20/D 1.428(lit.)
- Flash point:
- 185 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform, Ethyl Acetate
- form
- Liquid
- color
- Clear colorless to slightly yellow
- Specific Gravity
- 1.018
- optical activity
- [α]25/D 31°, neat
- Water Solubility
- insoluble
- BRN
- 5246881
- InChIKey
- YLNSNVGRSIOCEU-ZCFIWIBFSA-N
- CAS DataBase Reference
- 60456-26-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-42/43
- Safety Statements
- 23-36/37-45-36/37/39-26
- RIDADR
- 2810
- WGK Germany
- 3
- F
- 10-21
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29156000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 338125
- Product name
- (R)-(?)-Glycidyl butyrate
- Purity
- 96%
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- G0282
- Product name
- (R)-Glycidyl Butyrate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- G0282
- Product name
- (R)-Glycidyl Butyrate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $186
- Updated
- 2025/07/31
- Product number
- O847090
- Product name
- (2R)-2-OxiranylmethylEsterButanoicAcid
- Packaging
- 50g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 39555
- Product name
- (R)-Glycidylbutyrate,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 5G
- Price
- $72.22
- Updated
- 2021/12/16
(R)-Glycidyl butyrate Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liqui
Uses
(2R)-2-Oxiranylmethyl Ester Butanoic Acid is a reagent used in the synthesis of glycidol, a stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraulic fluids; epoxy resin diluent.
Uses
(R)-Glycidyl butyrate is a reagent used in the synthesis of glycidol, a stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraul ic fluids; epoxy resin diluent.
Synthesis
890051-54-4
60456-26-0
(S)-3-Chloro-1,2-propanediol 1-(n-butyrate) (50.0 g, 0.277 mol, optical purity 99% ee) was used as a raw material and dissolved in 1,2-dichloroethane (200 ml). Potassium tert-butoxide (32.6 g, 0.291 mol) was added to the solution under cooling conditions in an ice bath. The reaction mixture was stirred for 1 hour. After completion of the reaction, the mixture was transferred to a partition funnel and washed twice with water (200 ml). The organic layer was concentrated under reduced pressure to give (R)-glycidyl butyrate (28.7 g, 72.0% yield). The optical purity of the target product was 99% ee as determined by HPLC.
References
[1] Letters in Organic Chemistry, 2011, vol. 8, # 4, p. 242 - 243
[2] Tetrahedron Letters, 2006, vol. 47, # 20, p. 3453 - 3457
[3] Patent: US2004/24254, 2004, A1. Location in patent: Page 6
(R)-Glycidyl butyrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-Glycidyl butyrate manufacturers
- Product
- (R)-Glycidyl butyrate 60456-26-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-26
- Product
- (R)-Glycidyl butyrate 60456-26-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31
- Product
- (R)-Glycidyl butyrate 60456-26-0
- Price
- US $20.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-10-26