GUVACINE HYDROCHLORIDE

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GUVACINE HYDROCHLORIDE

Product Name: GUVACINE HYDROCHLORIDE
CAS No.: 498-96-4
Chemical Name: GUVACINE HYDROCHLORIDE
Synonyms: GUVACINE;GUVACINE-HCL;1,2,5,6-tetrahydronicotinic acid;1,2,5,6-tetrahydro-3-pyridinecarboxylic acid;1,2,5,6-Tetrahydropyridine-3-carboxylic acid;1,2,3,6-tetrahydropyridine-5-carboxylic acid;3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-;1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE;1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl)
CBNumber: CB2165839
Molecular Formula: C6H9NO2
Formula Weight: 127.14
MOL File: 498-96-4.mol

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GUVACINE HYDROCHLORIDE Property

Melting point:: 295°C (rough estimate)
Boiling point:: 235.91°C (rough estimate)
Density: 1.1931 (rough estimate)
refractive index: 1.4645 (estimate)
storage temp.: Store at RT
solubility: H₂O: soluble
form: solid
pka: 3.61±0.20(Predicted)
color: white
CAS DataBase Reference: 498-96-4

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 255418
Product name: Guvacine hydrochloride
Packaging: 100mg
Price: $446
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0004202
Product name: GUVACINE
Purity: 95.00%
Packaging: 50MG
Price: $258.3
Updated: 2021/12/16

ChemScene

Product number: CS-0022753
Product name: Guvacine
Packaging: 1mg
Price: $150
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb105361
Product name: Guvacine hydrochloride
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0004202
Product name: GUVACINE
Purity: 95.00%
Packaging: 100MG
Price: $702.19
Updated: 2021/12/16

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GUVACINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.

Definition

ChEBI: A alpha,beta-unsaturated monocarboxylic acid that is nicotinic acid which has been hydrogenated at the 1-2 and 5-6 positions of the pyridine ring.

Biological Activity

Specific GABA uptake inhibitor. IC 50 values are 14, 58, 119 and 1870 mM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.

GUVACINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GUVACINE HYDROCHLORIDE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Guvacine 498-96-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-23

Career Henan Chemical Co

Product: GUVACINE HYDROCHLORIDE 498-96-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-12

498-96-4, GUVACINE HYDROCHLORIDERelated Search:

ARECAIDINE BUT-2-YNYL ESTER TOSYLATE ARECAIDINE HYDROCHLORIDE GUVACINE HYDROCHLORIDE ARECOLINE HYDROCHLORIDE METHYL 4-AMINO-1-BENZYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE, 99 Arecoline hydrobromide ethyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate ARECAIDINE PROPARGYL ESTER TOSYLATE 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE ECGONIDINE METHYL ESTER MESYLATE ANHYDROECGONINE HYDROCHLORIDE 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE ARECAIDINE PROPARGYL ESTER HYDROBROMIDE (APE) arecoline GUVACINE HYDROCHLORIDE N-BENZYL-3-CARBOMETHOXY-4-PIPERIDONE, SODIUM SALT MONOHYDRATE, TECH. RARECHEM AX KI 5017 Nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-4-(2-methylpiperidino)-, m ethyl ester, hydrochloride, hydrate

GUVACINE

1,2,5,6-tetrahydro-3-pyridinecarboxylic acid

1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

GUVACINE-HCL

1,2,5,6-tetrahydronicotinic acid

1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl)

1,2,5,6-Tetrahydropyridine-3-carboxylic acid

3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-

1,2,3,6-tetrahydropyridine-5-carboxylic acid

498-96-4

C5H8NCOOH

GABA uptake inhibitor.

BioChemical

Cell Signaling and Neuroscience

Cell Biology

GABA and Glycine Receptor Modulators

Ligand-Gated Ion Channels

Ion Channels

GABA/Glycine receptor