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GUVACINE HYDROCHLORIDE

Product Name
GUVACINE HYDROCHLORIDE
CAS No.
498-96-4
Chemical Name
GUVACINE HYDROCHLORIDE
Synonyms
GUVACINE;GUVACINE-HCL;1,2,5,6-tetrahydronicotinic acid;1,2,5,6-tetrahydro-3-pyridinecarboxylic acid;1,2,5,6-Tetrahydropyridine-3-carboxylic acid;1,2,3,6-tetrahydropyridine-5-carboxylic acid;3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-;1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE;1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl)
CBNumber
CB2165839
Molecular Formula
C6H9NO2
Formula Weight
127.14
MOL File
498-96-4.mol
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GUVACINE HYDROCHLORIDE Property

Melting point:
295°C (rough estimate)
Boiling point:
235.91°C (rough estimate)
Density 
1.1931 (rough estimate)
refractive index 
1.4645 (estimate)
storage temp. 
Store at RT
solubility 
H2O: soluble
form 
solid
pka
3.61±0.20(Predicted)
color 
white
CAS DataBase Reference
498-96-4
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
255418
Product name
Guvacine hydrochloride
Packaging
100mg
Price
$446
Updated
2021/12/16
ChemScene
Product number
CS-0022753
Product name
Guvacine
Packaging
1mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0004202
Product name
GUVACINE
Purity
95.00%
Packaging
50MG
Price
$258.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105361
Product name
Guvacine hydrochloride
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0004202
Product name
GUVACINE
Purity
95.00%
Packaging
100MG
Price
$702.19
Updated
2021/12/16
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GUVACINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.

Definition

ChEBI: A alpha,beta-unsaturated monocarboxylic acid that is nicotinic acid which has been hydrogenated at the 1-2 and 5-6 positions of the pyridine ring.

Biological Activity

Specific GABA uptake inhibitor. IC 50 values are 14, 58, 119 and 1870 mM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.

GUVACINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GUVACINE HYDROCHLORIDE Suppliers

China 88 Germany 2 Japan 1 Switzerland 2 United Kingdom 3 United States 15 Global 111
Nacalai Tesque, Inc.
Tel
--
Fax
--
Email
info-tech@nacalai.co.jp
Country
Japan
ProdList
6046
Advantage
75
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View Lastest Price from GUVACINE HYDROCHLORIDE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Guvacine 498-96-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-23
Career Henan Chemical Co
Product
GUVACINE HYDROCHLORIDE 498-96-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

498-96-4, GUVACINE HYDROCHLORIDERelated Search:

ARECAIDINE BUT-2-YNYL ESTER TOSYLATE ARECAIDINE HYDROCHLORIDE GUVACINE HYDROCHLORIDE ARECOLINE HYDROCHLORIDE METHYL 4-AMINO-1-BENZYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE, 99 Arecoline hydrobromide ethyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate ARECAIDINE PROPARGYL ESTER TOSYLATE 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE ECGONIDINE METHYL ESTER MESYLATE ANHYDROECGONINE HYDROCHLORIDE 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE ARECAIDINE PROPARGYL ESTER HYDROBROMIDE (APE) arecoline GUVACINE HYDROCHLORIDE N-BENZYL-3-CARBOMETHOXY-4-PIPERIDONE, SODIUM SALT MONOHYDRATE, TECH. RARECHEM AX KI 5017 Nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-4-(2-methylpiperidino)-, m ethyl ester, hydrochloride, hydrate

  • GUVACINE
  • 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid
  • 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
  • GUVACINE-HCL
  • 1,2,5,6-tetrahydronicotinic acid
  • 1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl)
  • 1,2,5,6-Tetrahydropyridine-3-carboxylic acid
  • 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-
  • 1,2,3,6-tetrahydropyridine-5-carboxylic acid
  • 498-96-4
  • C5H8NCOOH
  • GABA uptake inhibitor.
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • GABA and Glycine Receptor Modulators
  • Ligand-Gated Ion Channels
  • Ion Channels
  • GABA/Glycine receptor