ChemicalBook > CAS DataBase List > (R)-(-)-1-Cyclohexylethylamine

(R)-(-)-1-Cyclohexylethylamine

Product Name
(R)-(-)-1-Cyclohexylethylamine
CAS No.
5913-13-3
Chemical Name
(R)-(-)-1-Cyclohexylethylamine
Synonyms
(R)-1-CYCLOHEXYLETHYLAMINE;(R)-1-Cyclohexylethanamine;(1R)-1-Cyclohexylethanamine;[(1R)-1-Cyclohexylethyl]amine;(R)-(-)-1-CYCLOHEXYLETHYLAMINE;(1R)-1-cyclohexylethan-1-amine;(R)-alpha-cyclohexanemethylamine;(R)-(-)-(1-Aminoethyl)cyclohexane;(R)-(-)-1-CYCLOHEXYLETHYLAMINE 98%;(R)-(-)-1-Cyclohexylethylamine >
CBNumber
CB2170978
Molecular Formula
C8H17N
Formula Weight
127.23
MOL File
5913-13-3.mol
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(R)-(-)-1-Cyclohexylethylamine Property

Melting point:
-15°C (estimate)
alpha 
-3.8 º (NEAT)
Boiling point:
177-178 °C (lit.)
Density 
0.866 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.463
Flash point:
126 °F
pka
10.89±0.29(Predicted)
form 
clear liquid
color 
Colorless to Almost colorless
optical activity
[α]20/D 4°, neat &_& [α]20/D -3.8±0.3°, neat
Water Solubility 
Miscible with acetone, chloroform,dimethyl sulfoxide, ethanol, methanol, ether, petroleum ether and dichloromethane. Insoluble in water.
Sensitive 
Air Sensitive
BRN 
2935070
CAS DataBase Reference
5913-13-3(CAS DataBase Reference)
NIST Chemistry Reference
R-(-)-Cyclohexylethylamine(5913-13-3)
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Safety

Hazard Codes 
C
Risk Statements 
10-21/22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2734 8/PG 2
WGK Germany 
3
F 
3-10-23
HazardClass 
8
PackingGroup 
II
HS Code 
2921309990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
336505
Product name
(R)-(?)-1-Cyclohexylethylamine
Purity
98%
Packaging
5g
Price
$136
Updated
2024/03/01
TCI Chemical
Product number
C1541
Product name
(R)-(-)-1-Cyclohexylethylamine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$151
Updated
2024/03/01
TCI Chemical
Product number
C1541
Product name
(R)-(-)-1-Cyclohexylethylamine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$431
Updated
2024/03/01
Alfa Aesar
Product number
L19051
Product name
(R)-(-)-1-Cyclohexylethylamine, ChiPros 98%, ee 94+%
Packaging
1g
Price
$23.65
Updated
2024/03/01
Alfa Aesar
Product number
L19051
Product name
(R)-(-)-1-Cyclohexylethylamine, ChiPros 98%, ee 94+%
Packaging
5g
Price
$51.65
Updated
2024/03/01
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(R)-(-)-1-Cyclohexylethylamine Chemical Properties,Usage,Production

Chemical Properties

optical purity >99% ee

Uses

(R)-(-)-1-Cyclohexylethylamine is used in the preparation of benzylidene(1-cyclohexylethyl)amine by reacting with benzaldehyde. It is also used to prepare chiral polymethacrylamides, which are employed as stationary phases for the liquid-chromatographic resolution of racemic amides. In addition to this, it is used in the preparation of polyamides bound to silica gel for high performance liquid chromatography, which are pressure-stable.

Uses

(R)-(-)-1-Cyclohexylethylamine may be used in the preparation of a chiral calix[4]arene Schiff base derivatives with potential enantioselective recognition ability towards amines.

General Description

(R)-(-)-1-Cyclohexylethylamine is a chiral amine mainly used as a resolving agent for racemic compounds.

Purification Methods

Purify it by conversion to the bitartrate salt (m 172o), then decomposing with strong alkali and extracting into Et2O, drying (KOH), filtering, evaporating and distilling. The hydrochloride salt has m 242o (from EtOH/Et2O), [] D -5.0o (c 10 H2O, from (+) amine). The oxalate salt has m 132o (from H2O). The (±)-base has b 176-178o/760mm, and HCl has m 237-238o. [Reihlen et al. Justus Liebigs Ann Chem 532 247 1938, Leithe Chem Ber 65 660 1932, Beilstein 12 III 95.]

(R)-(-)-1-Cyclohexylethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-1-Cyclohexylethylamine Suppliers

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5913-13-3, (R)-(-)-1-CyclohexylethylamineRelated Search:

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  • (<i>R</i>)-(-)-1-Cyclohexylethylamine
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  • (R)-(-)-1-CYCLOHEXYLETHYLAMINE 98%
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  • (r)-(-)-α-methylcyclohexanemethylamine
  • (R)-(-)-1-CYCLOHEXYLETHYLAMINE: CHIPROS 98%, EE 94%
  • (1R)-1-Cyclohexylethanamine
  • (R)-1-Cyclohexylethanamine
  • [(1R)-1-Cyclohexylethyl]amine
  • [R,(-)]-α-Methylcyclohexanemethanamine
  • (R)-(-)-1-Cyclohexylethylamine, ChiPros\(tm, 98% ee 94+%
  • (R)-(-)-1-CYCLOHEXYLETHYLAMINE, CHIPROS 98%, EE 94+%
  • (R)-(-)-1-Cyclohexylethylamine &gt
  • Cyclohexanemethanamine, α-methyl-, (αR)-
  • (R)-(-)-(1-Aminoethyl)cyclohexane
  • (aR)-a-methyl-cyclohexanemethanamine
  • (1R)-1-cyclohexylethan-1-amine
  • 5913-13-3
  • C6H11CHCH3NH2
  • Amines (Chiral)
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  • UV-VIS
  • Asymmetric Synthesis
  • Amines
  • Amines (Chiral)
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