ChemicalBook > CAS DataBase List > Pivaldehyde

Pivaldehyde

Product Name
Pivaldehyde
CAS No.
630-19-3
Chemical Name
Pivaldehyde
Synonyms
PIVALALDEHYDE;PAL;TRIMETHYLACETALDEHYDE;2,2-DIMETHYLPROPANAL;Pivalic aldehyde;tert-Pentanal;propanal,2,2-dimethyl-;LRIT1;LRRC21;NSC 22043
CBNumber
CB2174507
Molecular Formula
C5H10O
Formula Weight
86.13
MOL File
630-19-3.mol
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Pivaldehyde Property

Melting point:
6 °C(lit.)
Boiling point:
74 °C730 mm Hg(lit.)
Density 
0.793 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.378(lit.)
Flash point:
4 °F
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Liquid
color 
Clear colorless
Specific Gravity
0.793
Water Solubility 
Negligible
Sensitive 
Air Sensitive
BRN 
506060
Dielectric constant
9.0500000000000007
Stability:
Air Sensitive, Volatile
InChIKey
FJJYHTVHBVXEEQ-UHFFFAOYSA-N
CAS DataBase Reference
630-19-3(CAS DataBase Reference)
NIST Chemistry Reference
Propanal, 2,2-dimethyl-(630-19-3)
EPA Substance Registry System
Propanal, 2,2-dimethyl- (630-19-3)
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Safety

Hazard Codes 
F,Xi,F+
Risk Statements 
11-37/38-43
Safety Statements 
16-23-33-24
RIDADR 
UN 1989 3/PG 2
WGK Germany 
3
F 
8
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29121900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T71501
Product name
Trimethylacetaldehyde
Purity
96%
Packaging
5ml
Price
$65.7
Updated
2024/03/01
Sigma-Aldrich
Product number
T71501
Product name
Trimethylacetaldehyde
Purity
96%
Packaging
25ml
Price
$240
Updated
2024/03/01
TCI Chemical
Product number
P0847
Product name
Pivalaldehyde
Purity
>95.0%(GC)
Packaging
5mL
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
P0847
Product name
Pivalaldehyde
Purity
>95.0%(GC)
Packaging
25mL
Price
$146
Updated
2024/03/01
Alfa Aesar
Product number
A15013
Product name
Trimethylacetaldehyde, 95%
Packaging
5g
Price
$67.65
Updated
2024/03/01
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Pivaldehyde Chemical Properties,Usage,Production

Description

Trimethylacetaldehyde (also known as Pivaldehyde) is the trimethyl form of acetaldehyde. It is an aldehyde with a sterically bulky R group, the tertiary-butyl group being attached to the carbonyl, >C=O. It is a useful reagent in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It is useful in streoselective synthesis application as well as in aldol condensation reactions. As a derivative of acetaldehyde, trimethyl acetaldehyde can be used for the production of acetate. It can also be used as the precursor for manufacturing of pyridine derivatives, pentaerythritol, and crotonaldehyde.

Chemical Properties

Clear colorless liquid

Uses

Commonly used building block in aldol condensation reactions.

Uses

Trimethylacetaldehyde is used as a stereoselective synthesis application. It is also used as a building block used in aldol condensation reactions. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Definition

ChEBI: 2,2-dimethylpropanal is a member of the class of propanals that is propanal substituted by two methyl groups at position 2. It is a member of propanals and a 2-methyl-branched fatty aldehyde.

Application

Pivaldehyde is a hazardous by-product released from engine exhaust and is often used as a raw material for organic synthesis or as a reagent in chemical reactions. It can be copolymerised with aldehyde anions, such as acrolein, to prepare unsaturated polyacetals, or a TBPB initiated decarbonylative cascade cyclization of ortho-cyanoarylacrylamides with pivaldehyde leads to tert-butyl containing quinolone-2,4(1H,3H)-diones by formation of both C(sp3)–C(sp3) and C(sp3)–C(sp2) bonds. As well as probing the absolute rate constants of its autoxidation, etc[1-3].

References

[1] A. LAPENA; R. S; J L Mateo. Anionic copolymerization of acrolein with aldehydes. III[J]. Journal of Polymer Science: Polymer Symposia, 1973. DOI:10.1002/polc.5070420133.
[2] CUI ZHANG. Decarbonylative cascade cyclization of ortho-cyanoarylacrylamides with pivaldehyde: Access to tert-butyl containing quinolone-2,4(1H,3H)-diones[J]. Tetrahedron, 2022. DOI:10.1016/j.tet.2021.132547.
[3] G. ZAIKOV  K. I  J Howard. Absolute rate constants for hydrocarbon autoxidation. XIII. Aldehydes: photo-oxidation, co-oxidation, and inhibition[J]. Canadian Journal of Chemistry, 1969. DOI:10.1139/V69-500.

References

Ho, Tse Lok, et al. Pivaldehyde. Fieser and Fieser's Reagents for Organic Synthesis. John Wiley & Sons, Inc. 2006.
https://en.wikipedia.org/wiki/Acetaldehyde#Uses
https://en.wikipedia.org/wiki/Pivaldehyde
https://www.alfa.com/en/catalog/A15013/

Pivaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

Clomazone neopentyl glycol (S)-2-Methylproline
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Pivaldehyde Suppliers

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View Lastest Price from Pivaldehyde manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Pivaldehyde 630-19-3
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-17
Handan Huajun chemicals Co.,Ltd
Product
Pivalaldehyde 630-19-3
Price
US $190.00/kg
Min. Order
1kg
Purity
96.0%
Supply Ability
500MT
Release date
2024-01-22
Hebei Chuanghai Biotechnology Co,.LTD
Product
Pivaldehyde 630-19-3
Price
US $9.10/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-20

630-19-3, PivaldehydeRelated Search:

Pivaloyl chloride Neopentylamine Pivalic acid Trimethylacetonitrile Iodomethyl pivalate PotassiuM triMethylacetate, 95% TRIMETHYLACETIC ANHYDRIDE 2,2-DIMETHYL-6,6,7,7,8,8,8-HEPTAFLUORO-3,5-OCTANEDIONE TETRAMETHYL-1,3-CYCLOBUTANEDIONE CHLOROMETHYL PIVALATE Diethyl 1,1-cyclopropanedicarboxylate 1-Phenyl-1-cyclopropanecarboxylic acid PR(TMHD)3 1-Bromopinacolone TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Trimethylacetaldehyde oxime Propionaldehyde tert-Butanol Trimethylacetaldehyde

  • PAL
  • PIVALALDEHYDE
  • PIVALDEHYDE
  • TRIMETHYLACETALDEHYDE
  • 2,2-dimethyl-propana
  • 2,2-Dimethylpropionaldehyd
  • 2-Dimethylpropanal
  • alpha,alpha-Dimethylpropionaldehyde
  • Neopentaldehyde
  • Neopentanal
  • Pivalic aldehyde
  • Pivalicaldehyde
  • propanal,2,2-dimethyl-
  • tert-Butylformaldehyde
  • tert-C4H9CHO
  • tert-Pentanal
  • tert-Valeraldehyde
  • Trimethylacetaldehyd
  • α,α-Dimethylpropanal
  • α,α-Dimethylpropionaldehyde
  • 2,2-DIMETHYLPROPIONALDEHYDE
  • 2,2-DIMETHYLPROPANAL
  • 2,2-DIMETHYL-1-PROPANAL
  • Pivaldehyde, 97%, AcroSeal
  • Three Methylaldehyde
  • Especially aMyl aldehyde
  • Pivalaldehyde Trimethylacetaldehyde 2,2-Dimethylpropanal 2,2-Dimethylpropionaldehyde
  • ANTI-LRIT1 (C-TERM) antibody produced in rabbit
  • immunoglobulin-like domain and transmembrane domain-containing protein 1
  • Leucine-rich repeat
  • LRIT1
  • LRRC21
  • Trimethylacetaldehyde solution, 75 wt. % in tert-butanol
  • Pivalaldehyde (contains tert-Butanol)
  • Pivaldehyde2,2-Dimethylpropanal Pivalic aldehyde
  • 2,2-dimethylolpropanal
  • Pivalaldehyde, Trimethylacetaldehyde
  • Trimethylacetaldehyde, remainder 20% tert-butanol
  • Trimethylacetaldehyde,ca75%intert-butanol
  • Trimethylacetaldehyde,97%
  • TRIMETHYL ACETALDEHYDE(PIVALDEHYDE)
  • Pivaldehyde,97%
  • Pivaldehyde, remainder 20% tert-butanol,ca 80%
  • Trimethylacetaldehyde, 98+%
  • Trimethylacetaldehyde,Pivalaldehyde, Trimethylacetaldehyde
  • Pivaldehyde, AcroSeal, 97%
  • Pivaldehyde, 97% 25GR
  • Pivaldehyde, AcroSeal, 97% 100ML
  • 2,2-DiMethylpropanone
  • NSC 22043
  • 2,2-Dimethylpropanal 2,2-Dimethylpropionaldehyde Trimethylacetaldehyde
  • Pivaldehyde, Trimethylacetaldehyde
  • Pivalaldehyde&gt
  • Pivalyl Aldehyde
  • Pivaldehyde, 96%, AcroSeal&trade
  • PIVALDEHYDE Extra Pure
  • Pivalaldehyde (7CI, 8CI)
  • 630-19-3