BOC-D-THR-OH

Product Name: BOC-D-THR-OH
CAS No.: 55674-67-4
Chemical Name: BOC-D-THR-OH
Synonyms: BOC-D-THR;BOC-D-THR-OH;BOC-D-THREONINE;N-Boc-L-threonine;BOC-D-THR-OH USP/EP/BP;BOC-D-THREONINE extrapure;N-ALPHA-T-BOC-D-THREONINE;Boc-D-threonine≥ 98% (HPLC);BOC-D-Threonine(BOC-D-Thr-OH);N-Boc-D-threonine Boc-D-Thr-OH
CBNumber: CB2177386
Molecular Formula: C9H17NO5
Formula Weight: 219.24
MOL File: 55674-67-4.mol

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BOC-D-THR-OH Property

Melting point:: 81 °C
refractive index: 9 ° (C=1, AcOH)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Solid
color: White to Almost white
Water Solubility: Slightly soluble in water.
CAS DataBase Reference: 55674-67-4(CAS DataBase Reference)

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Safety

HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53102
Product name: Boc-D-Thr-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 5 g
Price: $63
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53102
Product name: Boc-D-Thr-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 25 g
Price: $628
Updated: 2025/07/31

TCI Chemical

Product number: B2990
Product name: N-(tert-Butoxycarbonyl)-D-threonine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $335
Updated: 2025/07/31

TRC

Product number: B668000
Product name: N-Boc-D-threonine
Packaging: 1g
Price: $55
Updated: 2021/12/16

Usbiological

Product number: 264831
Product name: Boc-D-threonine
Packaging: 5g
Price: $360
Updated: 2021/12/16

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BOC-D-THR-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

It is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. Also used as a synthetic intermediate for the production of chiral antibiotics.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

28954-12-3

24424-99-5

2592-18-9

The general procedure for the synthesis of (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid from (2S,3S)-2-amino-3-hydroxybutyric acid and di-tert-butyl dicarbonate is as follows: 1. di-tert-butyl dicarbonate (550 mg, 2.52 mmol) was added to a mixture of methanol (2.5 mL) and water (2.5 mL) containing L-isothreonine (250 mg, 2.10 mmol) and sodium bicarbonate (529 mg, 6.30 mmol) at 0 °C. 2. The reaction mixture was gradually warmed to room temperature and stirred continuously at room temperature for 18 hours. 3. Upon completion of the reaction, the methanol was removed by concentration and the remaining aqueous phase was adjusted to pH 3~4 with 6N hydrochloric acid solution. 4. The acidified aqueous phase was extracted with ether (3 times) and all organic phases were combined. 5. The organic phase was washed with water and brine sequentially, and then dried with anhydrous sodium sulfate. 6. The desiccant was removed by filtration, and the filtrate was concentrated under vacuum and further dried under vacuum for 24 h. (2R,3S)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid (304 mg) was obtained as a white solid. Product identification: LCMS retention time (Rt) = 0.36 min; mass spectrum (MS) m/z 220 [M + H]+, m/z 218 [M-H]-.

References

[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 38, p. 6935 - 6960
[2] Journal of the American Chemical Society, 2000, vol. 122, # 41, p. 10214 - 10215
[3] Journal of the American Chemical Society, 2003, vol. 125, # 7, p. 1877 - 1887
[4] Journal of Organic Chemistry, 1982, vol. 47, # 26, p. 5160 - 5167
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 16, p. 4329 - 4332

BOC-D-THR-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-THR-OH Suppliers

Americas 1 China 132 Europe 1 France 1 India 6 Japan 3 Switzerland 1 United Kingdom 6 United States 23 Global 174

ChemPep, Inc.

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View Lastest Price from BOC-D-THR-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-D-Thr-OH 55674-67-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-14

Career Henan Chemical Co

Product: BOC-D-THR-OH 55674-67-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

55674-67-4, BOC-D-THR-OHRelated Search:

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N-Boc-L-threonine

BOC-D-Threonine(BOC-D-Thr-OH)

N-Boc-D-threonine Boc-D-Thr-OH

(Tert-Butoxy)Carbonyl D-Thr-OH

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(2R,3S)-2-((tert-Butoxycarbonyl)aMino)-3-hydroxybutanoic acid

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N-(tert-Butoxycarbonyl)-D-threonine &gt

D-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-

BOC-D-THR-OH USP/EP/BP

55674-67-4

Threonine [Thr, T]

Boc-Amino Acids and Derivative

Amino Acids

Amino Acids (N-Protected)

Biochemistry

Boc-Amino Acids