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D-Glucosamine hydrochloride

Product Name
D-Glucosamine hydrochloride
CAS No.
66-84-2
Chemical Name
D-Glucosamine hydrochloride
Synonyms
GLUCOSAMINE HYDROCHLORIDE;GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D-Glucosamine Salt;Glucosamine for system suitability CRS;2-amino-2-deoxy-D-glucose hydrochloride (1:1);cosamin;NSC 758;D-GLCN HCL;NSC 234443
CBNumber
CB2181059
Molecular Formula
C6H14ClNO5
Formula Weight
215.63
MOL File
66-84-2.mol
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D-Glucosamine hydrochloride Property

Melting point:
190-194 °C (dec.)(lit.)
alpha 
72.5 º (c=2, H2O, 5hrs.)
refractive index 
72 ° (C=1, H2O)
storage temp. 
2-8°C
solubility 
H2O: 0.1 g/mL, clear, colorless
form 
crystalline
color 
White
Water Solubility 
soluble
Merck 
14,4458
BRN 
4157370
Stability:
Stable. Incompatible with strong oxidizing agents. Combustible.
InChI
InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3
InChIKey
QKPLRMLTKYXDST-LPRXMDNASA-N
SMILES
[C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl |&1:0,5,7,9,r|
LogP
-2.375 (est)
CAS DataBase Reference
66-84-2(CAS DataBase Reference)
EPA Substance Registry System
D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)
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Safety

Hazard Codes 
F,Xi,Xn
Risk Statements 
21-36/38-46-62-63
Safety Statements 
24/25-53-36/37-26-25
WGK Germany 
2
RTECS 
LZ6665000
3-10
Hazard Note 
Highly Flammable
TSCA 
Yes
HS Code 
29329985
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G1514
Product name
D-(+)-Glucosamine hydrochloride
Purity
≥99%, BioReagent, suitable for cell culture
Packaging
100g
Price
$77.4
Updated
2024/03/01
Sigma-Aldrich
Product number
1294207
Product name
Glucosamine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$394
Updated
2024/03/01
TCI Chemical
Product number
G0044
Product name
D-(+)-Glucosamine Hydrochloride
Purity
>98.0%(T)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
G0044
Product name
D-(+)-Glucosamine Hydrochloride
Purity
>98.0%(T)
Packaging
500g
Price
$155
Updated
2024/03/01
Alfa Aesar
Product number
A15532
Product name
D-Glucosamine hydrochloride, 98+%
Packaging
50g
Price
$36.5
Updated
2023/06/20
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D-Glucosamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties.

Uses

Novel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs.

Uses

Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.

General Description

Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine.

Biochem/physiol Actions

Glucosamine is preferred as a nutritional supplement?for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans?and?glycosaminoglycans.

Purification Methods

Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give  anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]

D-Glucosamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Glucosamine hydrochloride Suppliers

QINGDAO WANYUAN MOUNTAIN BIOTECH CO.,LTD
Tel
0532-0532-66720179 15092119928
Email
cuiningning@bionutrichem.com
Country
China
ProdList
109
Advantage
58
Wuhan Penglei Biological Technology Co., Ltd.
Tel
18672616696
Email
229092275@qq.com
Country
China
ProdList
707
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58
Shanghai Yingxin laboratory equipment Co., Ltd
Tel
021-021-59178156 15300768757
Email
359382369@qq.com
Country
China
ProdList
10367
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58
Hubei Hicks Biochemical Co., Ltd
Tel
17362916295; 17362916295
Email
w17362916295@163.com
Country
China
ProdList
4054
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58
Shandong Aicai Biotechnology Co. , Ltd.
Tel
135-37016375 13573016375
Email
3358761976@qq.com
Country
China
ProdList
501
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58
Zhengbainian (Shanghai) International Trade Co., Ltd.
Tel
13381511189
Email
juetubt1988@163.com
Country
China
ProdList
411
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58
Xi'AnTongZeBiotechCo.,Ltd
Tel
+86-18591971926 +86-18591971926
Email
3516471159@qq.com
Country
China
ProdList
154
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58
Hubei Shiteng Chemical Technology Co. LTD
Tel
189-71850150 19086915685
Email
1273131441@qq.com
Country
China
ProdList
4998
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
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View Lastest Price from D-Glucosamine hydrochloride manufacturers

Hangzhou Zelixir Biotech Co., Ltd.
Product
Glucosamine Hydrochloride 66-84-2
Price
US $0.00/kg
Min. Order
0.1kg
Purity
99%
Supply Ability
100MT
Release date
2023-12-04
Hebei Dangtong Import and export Co LTD
Product
D-Glucosamine hydrochloride 66-84-2
Price
US $8.00-7.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100Tons
Release date
2023-03-03
zhuzhou dingcheng meihei comestic co.,ltd
Product
glucosamine Hcl 66-84-2
Price
US $20.00/Box
Min. Order
1Box
Purity
99.99%
Supply Ability
10000000000
Release date
2024-01-03

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