description application Purification methods Chemical properties Uses chemical synthesis
ChemicalBook > CAS DataBase List > Dimethyl sulfone

Dimethyl sulfone

description application Purification methods Chemical properties Uses chemical synthesis
Product Name
Dimethyl sulfone
CAS No.
67-71-0
Chemical Name
Dimethyl sulfone
Synonyms
MSM;METHYL SULFONYL METHANE;METHYL SULFONE;DMSO2;Dimethylsulfon;(CH3)2SO2;Dimethyl sulfone solution;METHYLSULPHONE;DIMETHYL SULFONE;DMSO2
CBNumber
CB2193076
Molecular Formula
C2H6O2S
Formula Weight
94.13
MOL File
67-71-0.mol
More
Less

Dimethyl sulfone Property

Melting point:
107-109 °C (lit.)
Boiling point:
238 °C (lit.)
Density 
1,16 g/cm3
refractive index 
1.4226
Flash point:
290 °F
storage temp. 
Store below +30°C.
solubility 
150g/l
pka
28(at 25℃)
form 
Crystals or Crystalline Powder
color 
White
Odor
at 1.00?%. sulfurous burnt
Water Solubility 
150 g/L (20 ºC)
Merck 
14,3258
BRN 
1737717
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
HHVIBTZHLRERCL-UHFFFAOYSA-N
LogP
-1.074 (est)
CAS DataBase Reference
67-71-0(CAS DataBase Reference)
NIST Chemistry Reference
Dimethyl sulfone(67-71-0)
EPA Substance Registry System
Dimethyl sulfone (67-71-0)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
1
RTECS 
PB2785000
TSCA 
Yes
HS Code 
29309070
Toxicity
LD50 orally in Rabbit: 17000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
41867
Product name
Dimethyl sulfone
Purity
Standard for quantitative NMR, TraceCERT
Packaging
1g
Price
$208
Updated
2024/03/01
Sigma-Aldrich
Product number
1437600
Product name
Methylsulfonylmethane
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$394
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03284
Product name
Dimethyl sulfone
Purity
for synthesis
Packaging
5G
Price
$32.2
Updated
2022/05/15
TCI Chemical
Product number
M0509
Product name
Dimethyl Sulfone
Purity
>99.0%(GC)
Packaging
25g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
M0509
Product name
Dimethyl Sulfone
Purity
>99.0%(GC)
Packaging
500g
Price
$60
Updated
2024/03/01
More
Less

Dimethyl sulfone Chemical Properties,Usage,Production

description

Dimethyl Sulfone (MSM) is an organic sulfur-containing compound that occurs naturally in a variety of fruits, vegetables, grains, and animals including humans. a white, odorless, slightly bitter-tasting crystalline substance containing 34-percent elemental sulfur, MSM is a normal oxidative metabolite product of dimethyl sulfoxide (DMSO). Cow’s milk is the most abundant source of MSM, containing approximately 3.3 parts per million (ppm). Other foods containing MSM are coffee (1.6 ppm), tomatoes (trace to 0.86 ppm), tea (0.3 ppm), Swiss chard (0.05-0.18 ppm), beer (0.18 ppm), corn (up to 0.11 ppm), and alfalfa (0.07 ppm).MSM has been isolated from plants such as Equisetum arvense, also known as horsetail.
Dimethyl Sulfone has the ability to enhance the body to produce insulin, while it can promote carbohydrate metabolism. It is essential for the synthesis of human collagen. It can not only promote wound healing, but also contribute for metabolic and neurological health requirement of vitamin B and vitamin C, biotin synthesis and activation, so it is known as "naturally beautiful carbon material". Dimethyl Sulfone exists in human skin, hair, nails, bones, muscles and various organs. Once people who are lack of it will get health disorders or diseases. It is the main substance for people to maintain the balance of biological sulfur. It has therapeutic value and healthcare function for people. It is an essential drug for human survial and health protection.

application

  • Dimethyl sulfone can eliminate the virus, enhance blood circulation, soften tissue, relieve pain, strengthen sinews and bones, calm the spirit, enhance physical strength, maintain skin, make beauty salons, treat the arthritis, oral ulcers, asthma and constipation, dredge the blood vessels, Clear gastrointestinal toxins.
  • Dimethyl sulfone can be used as food and feed additives to supplement the organic sulfur nutrients for humans, pets and livestock.
  • For external use, it can make the skin smooth, supple muscles, and reduce pigmentation. Recently, it surges in the amount as the cosmetic additives.
  • In medicine, it has a good analgesic, it can promote wound healing and others.
  • Dimethyl sulfone is a good penetrant in medicines production.

Purification methods

Using different purification methods, the products contained different impurities. in the finished product is different purification methods are also different. In general, it is decolored by active carbon, demineralized by ion exchange, and then recrystallized the solvent, dried by vacuum. After that, it is sieved and added an antistatic agent and a slip agent, in order to meet the export requirements. There is no national or ministerial standards. Currently, the countries in the world continue to enforce corporate standards or contract specifications.

Chemical properties

white needle-like crystals. Melting point 109 ℃, boiling point 238 ℃, relative density 1.1702 (110/0 ℃), refractive index 1.4226, flash point 143 ℃. Soluble in water, ethanol, benzene, methanol and acetone, slightly soluble in ether and chloroform. Stink.

Uses

Use as high temperature solvent inorganic and organic substances, organic chemical raw materials, food additives and health products raw materials, also used as gas chromatography stationary phase (maximum use temperature 30 ℃, acetone as solvent) and analytical reagents.

chemical synthesis

Dimethyl sulfone is obtained by oxidizing methyl sulfone using nitric acid as oxidation. Methyl sulfone was oxidized at 140-145 ℃ by nitric oxide. After completion of the reaction, It was cooled and filtered to give white needles crude. Then vacuum distillation, collecting 138-145 ℃ (98.42kPa) distillate products which are the finished goods.

Chemical Properties

colourless crystals

Uses

Dimethyl sulfone is used as a high-temperature solvent for both inorganic and organic substances. It acts as an intermediate as well as medium in organic synthesis. It plays an important role as a carbon source by the airborne bacteria Afipia. It is also employed as an extraction solvent for the separation of aromatic compounds like benzene, toluene and xylenes from aliphatic hydrocarbons. Further, it is used in the polymerization process. It finds application in pharmaceuticals, agrochemicals, paint and coating materials.

Uses

Dimethyl sulfone is a high tempereture solvent for many inorganic and organic substances,it is used as antiinflammatory, antiproliferative, antiparasitic.

Definition

ChEBI: Sulfonyldimethane is a sulfone.

Synthesis Reference(s)

Journal of the American Chemical Society, 91, p. 3992, 1969 DOI: 10.1021/ja01042a075

Purification Methods

Crystallise the sulfone from water. Dry it over P2O5. [Beilstein 1 IV 1279.]

Dimethyl sulfone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dimethyl sulfone Suppliers

QINGDAO WANYUAN MOUNTAIN BIOTECH CO.,LTD
Tel
0532-0532-66720179 15092119928
Email
cuiningning@bionutrichem.com
Country
China
ProdList
74
Advantage
58
Guangzhou Dihao Medical Technology Co., Ltd
Tel
18602015453
Email
2667751176@qq.com
Country
China
ProdList
485
Advantage
58
Xi`an Tian Guangyuan Biotech Co., Ltd.
Tel
17391926474
Email
2539013658@qq.com
Country
China
ProdList
205
Advantage
58
Shandong Wankang Biotechnology Co. , Ltd.
Tel
131-7317-1119 13173171119
Email
918582503@qq.com
Country
China
ProdList
25
Advantage
58
Zhengbainian (Shanghai) International Trade Co., Ltd.
Tel
13381511189 13381511189
Email
1514630485@qq.com
Country
China
ProdList
457
Advantage
58
Hebei Zhongbei Jiamei Biological Technology Co., Ltd.
Tel
0311-89171450 15373918792
Email
3265217077@qq.com
Country
China
ProdList
45
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
More
Less

View Lastest Price from Dimethyl sulfone manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Dimethyl sulfone MSM 67-71-0
Price
US $0.00/KG
Min. Order
1KG
Purity
>99% HPLC
Supply Ability
1000KG
Release date
2022-09-19
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Dimethyl sulfone 67-71-0
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Dimethyl sulfone 67-71-0
Price
US $32.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-04-26

67-71-0, Dimethyl sulfoneRelated Search:


  • Methyl sulfone Sulfonyl bismethane
  • MSM
  • (CH3)2SO2
  • Methane, sulfonylbis-
  • Methane,sulfonylbis-
  • Methanesulfonylmethane
  • Sulfone, dimethyl-
  • METHYLSULPHONE
  • METHYL SULFONYL METHANE
  • METHYL SULFONE
  • DIMETHYL SULPHONE
  • DIMETHYL SULFONE
  • sulfonylbis-methan
  • sulfonylbismethane
  • Sulfonylbis-methane
  • Sulphonylbismethane
  • DimethylSulfone(DMS)
  • DimethylSulphoxideGr
  • Dimethylsulphone99%
  • DimethylSulphateForSynthesis
  • DimethylSulfoxideForHplc
  • DIMETHYL SULFOXIDE for UV spectroscopy
  • Dimethylsulphone 99%
  • Dimethylsulfone,98%
  • Methyl sulfonyl mathane
  • DMSO<sub>2</sub>
  • dimethyl sulfone (MSM)
  • METHYLSULFONYLMETHANE 80 MESH
  • sulfonyldimethane
  • dimethylsulfone,sulfonylbismethane
  • METHYLSULFONE,CRYSTAL
  • DMSO2
  • Dimethylsulfon
  • Dimethylsulfonic acid
  • Dimethyl sulfone ,99%
  • Dimethyl sulfone,Methyl sulfone
  • Methylsulfonylmethane (200 mg)
  • Methyl sulfone, 98% 500GR
  • Methyl sulfone,98%
  • DIMETHYL SULFONE FOR SYNTHESIS
  • DiMethyl sulfone , Methyl Sulfonyl Methane
  • MSM(MethylSulfonyl Methane)
  • Methane, 1,1'-sulfonylbis-
  • DimethylSulfone&gt
  • Dimethgl sulfone
  • Dimethyl sulfone solution
  • Dimethyl sulfone ISO 9001:2015 REACH
  • Methyl Sulfone, Msm, 67-71-0, Methyl Sulfonyl Methane, Methanesulfonyl Methane
  • Methylsulfonylmethane (F0F298)
  • Isoxaben Impurity 15
  • Dimethyl Sulfone, ≥ 99.0%
  • METHYL SULPHONYL METANE
  • 67-71-0
  • 61-71-0
  • C2H6O2S
  • Sulfur Compounds
  • Sulfones
  • Organic Building Blocks