Cefozopran

Product Name: Cefozopran
CAS No.: 113359-04-9
Chemical Name: Cefozopran
Synonyms: D01052;Firstci;sce2787;SCE-1787;Firstcin);CEFOZOPRAN;Cefozopran (inn);SCE2787;SCE 2787;SCE-2787：Fastocin;Cefozopran(SCE 2787)
CBNumber: CB2198495
Molecular Formula: C19H17N9O5S2
Formula Weight: 515.52
MOL File: 113359-04-9.mol

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Cefozopran Property

Melting point:: >300°C
storage temp.: Store at -20°C
solubility: Soluble in DMSO
CAS DataBase Reference: 113359-04-9(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific

Product number: H710
Product name: Cefozopran
Packaging: 5g
Price: $590
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001903
Product name: CEFOZOPRAN
Purity: 95.00%
Packaging: 10G
Price: $2243.59
Updated: 2021/12/16

AHH

Product number: MT-49084
Product name: Cefozopran
Purity: 98%
Packaging: 0.5g
Price: $910
Updated: 2021/12/16

DC Chemicals

Product number: DC8067
Product name: Cefozopran(SCE2787)
Purity: >98%
Packaging: 250mg
Price: $1000
Updated: 2021/12/16

Crysdot

Product number: CD31004510
Product name: Cefozopran
Purity: 98+%
Packaging: 50mg
Price: $122
Updated: 2021/12/16

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Cefozopran Chemical Properties,Usage,Production

Chemical Properties

White To Pale-Yellow Powder

Uses

Antibacterial

Definition

ChEBI: Cefozopran is a fourth-generation cephalosporin antibiotic having imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It is a cephalosporin, a member of thiadiazoles and an imidazopyridazine.

Antimicrobial activity

An aminothiazole cephalosporin formulated as the hydrochloride. Activity is similar to that of ceftazidime, but it is more active against methicillin-susceptible staphylococci (MIC 1 mg/L). Representative MICs against Gram-negative species are: Esch coli 0.25 mg/L; K. pneumoniae 1 mg/L; Ps. aeruginosa 1–8 mg/L. Activity against Acinetobacter spp., Sten. maltophilia and B. fragilis group is poor.
A 20-min infusion of 1.5 g achieved a plasma concentration of around 125 mg/L at the end of infusion. Almost 90% of the dose was excreted in the urine over 24 h. The mean terminal half-life was around 2 h. Adverse reactions appear to be typical of those of other group 6 cephalosporins.
It is available in Japan.

Cefozopran Preparation Products And Raw materials

Raw materials

2-Mercapto-5-methyl-1,3,4-thiadiazole Hexane Potassium iodide 2-Butanone Trifluoroacetic acid Pyridazine Phosphorus pentachloride Ethyl acetate Dichloromethane Formamide

Preparation Products

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Cefozopran Suppliers

Canada 1 China 83 Europe 3 Germany 1 India 2 South Korea 1 United Kingdom 4 United States 18 Global 113

MedChemexpress LLC

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Musechem

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BOC Sciences

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Medical Isotopes

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MedChemExpress

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Waterstone Technology, LLC

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2A PharmaChem USA

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3B Scientific Corporation

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APAC Pharmaceutical, LLC

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Fine Chem Trading LTD

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AK Scientific, Inc.

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BOSCHE SCIENTIFIC, LLC

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American Custom Chemicals Corporation

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113359-04-9, CefozopranRelated Search:

Thioacetamide N-Acetyl-L-cysteine Acetyl coenzyme A sodium salt Acetamide Acetylacetone 6-Aminocaproic acid ALTRENOGEST Glycine Acetyl chloride N,N-Dimethylacetamide Tris(hydroxymethyl)aminomethane DIACETAMIDE Cefazolin 2,1,3-Benzothiadiazole Acetaminophen 2-Mercapto-5-methyl-1,3,4-thiadiazole Cefotetan 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium inner salt

CEFOZOPRAN

sce2787

SCE2787;SCE 2787

Cefozopran(SCE 2787)

1-[[(6R,7R)-7-[[(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-imidazo[1,2-b]pyridazinium hydroxide inner salt

1-[[(6R,7R)-7-[[2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]imidazo[1,2-b]pyridazinium Inner Salt

Firstci

SCE-1787

Cefozopran (inn)

D01052

Firstcin)

SCE-2787：Fastocin

(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Parent nucleus of Cefozopran

Cefozopran USP/EP/BP

113359-04-9

C19H17N9O5S2

C19H18ClN9O5S2

Antibacterial

Intermediates & Fine Chemicals

Pharmaceuticals

Cefozopran Hydrochloride and its intermediates