5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine

Product Name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
CAS No.: 285984-25-0
Chemical Name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
Synonyms: STK234818;ZINC02527276;BUTTPARK 74\09-04;5-AMINO-3-T-BUTYL-1-P-TOLYL-PYRAZOLE;5-t-butyl-2-p-tolyl-2H-pyrazol-3-ylamine;5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE;3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-ylamine;3-TERT-BUTYL-1-(P-TOLYL)-1H-PYRAZOLE-5-AMINE;5-tert-butyl-2-(4-Methylphenyl)pyrazol-3-aMine;5-tert-butyl-2-(4-methylphenyl)-3-pyrazolamine
CBNumber: CB2206125
Molecular Formula: C14H19N3
Formula Weight: 229.32
MOL File: 285984-25-0.mol

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5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine Property

Boiling point:: 368.3±37.0 °C(Predicted)
Density: 1.06±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: 4.17±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C14H19N3/c1-10-5-7-11(8-6-10)17-13(15)9-12(16-17)14(2,3)4/h5-9H,15H2,1-4H3
InChIKey: ITHNHEWXIBNEDG-UHFFFAOYSA-N
SMILES: N1(C2=CC=C(C)C=C2)C(N)=CC(C(C)(C)C)=N1

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: JRD0050
Product name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
Purity: Aldrich
Packaging: 1g
Price: $259
Updated: 2025/07/31

TRC

Product number: B810518
Product name: 3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-amine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB51086
Product name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
Packaging: 100mg
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: V0035
Product name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
Packaging: 1g
Price: $81
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB51086
Product name: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine
Packaging: 500mg
Price: $170
Updated: 2021/12/16

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5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine Chemical Properties,Usage,Production

Synthesis

59997-51-2

637-60-5

285984-25-0

General procedure for the synthesis of 5-tert-butyl-2-p-tolyl-2H-pyrazol-3-amine from 4,4-dimethyl-3-oxopentanenitrile and 4-methylphenylhydrazine hydrochloride: 4-methylphenylhydrazine hydrochloride (5.20 g, 33 mmol) and 4,4-dimethyl-3-oxopentanenitrile (3.75 g, 30 mmol) were dissolved in an ethanol solution of 0.4 M HCl (100 mL) and heated at reflux for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 10-11 by slow addition of 1 M NaOH solution.Subsequently, the reaction mixture was partitioned between water and ethyl acetate. The aqueous phase was extracted twice with dichloromethane. All organic phases were combined, washed sequentially with water and saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. The crude product was recrystallized from a solvent mixture of ethyl acetate and petroleum ether to give 5-tert-butyl-2-p-tolyl-2H-pyrazol-3-amine (compound 25a) as a white solid (5.88 g, 86% yield).

References

[1] Patent: US2004/192653, 2004, A1
[2] Molecules, 2014, vol. 19, # 2, p. 2004 - 2028
[3] Molecules, 2015, vol. 20, # 9, p. 16604 - 16619
[4] Organic Process Research and Development, 2010, vol. 14, # 3, p. 650 - 656
[5] Journal of the American Chemical Society, 2009, vol. 131, # 37, p. 13286 - 13296

5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine Suppliers

China 83 Germany 2 India 1 Ukraine 1 United Kingdom 3 United States 16 Global 106

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

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View Lastest Price from 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine manufacturers

Career Henan Chemical Co

Product: 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamine 285984-25-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

285984-25-0, 5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-ylamineRelated Search:

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1H-Pyrazol-5-aMine, 3-(1,1-diMethylethyl)-1-(4-Methylphenyl)-

5-tert-butyl-2-(4-Methylphenyl)pyrazol-3-aMine

[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]amine

5-tert-butyl-2-(4-methylphenyl)-3-pyrazolamine

STK234818

ZINC02527276

5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE

3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-AMINE

5-AMINO-3-T-BUTYL-1-P-TOLYL-PYRAZOLE

5-t-butyl-2-p-tolyl-2H-pyrazol-3-ylamine

BUTTPARK 74\09-04

JR-13713, 3-Tert-butyl-1-p-tolyl-1H-pyrazol-5-amine, 95%

3-TERT-BUTYL-1-(P-TOLYL)-1H-PYRAZOLE-5-AMINE

3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-ylamine

5-Amino-3-tert-butyl-1-(4-methylphenyl)pyrazole

5-<i>tert</i>-Butyl-2-p-tolyl-2<i>H</i>-pyrazol-3-ylamine

285984-25-0

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