synthesis
ChemicalBook > CAS DataBase List > Ethyl 2-oxo-4-phenylbutyrate

Ethyl 2-oxo-4-phenylbutyrate

synthesis
Product Name
Ethyl 2-oxo-4-phenylbutyrate
CAS No.
64920-29-2
Chemical Name
Ethyl 2-oxo-4-phenylbutyrate
Synonyms
KETO ESTER;ETHYL BENZYLPYRUVATE;Ethyl 2-oxy-butyrate;2-oxo-4-phenylhexanoate;2 - oxo -4 - ethyl benzene;ETHYL-2-OXO-4-PHENYLBUTRATE;Ethy 2-oxo-4-phenylbutyrate;Ethyl α-oxobenzenebutanoate;ETHYL 2-OXO-4-PHENYLBUTYRATE;Ethyl-2-oxo-4-pheny1Butyrate
CBNumber
CB2207283
Molecular Formula
C12H14O3
Formula Weight
206.24
MOL File
64920-29-2.mol
More
Less

Ethyl 2-oxo-4-phenylbutyrate Property

Boiling point:
132 °C/2 mmHg (lit.)
Density 
1.091 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.504(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Oil
color 
Colourless
BRN 
2725083
CAS DataBase Reference
64920-29-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-24/25-36/37-26
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Alfa Aesar
Product number
B20148
Product name
Ethyl 2-oxo-4-phenylbutyrate, 90+%
Packaging
10g
Price
$42.65
Updated
2024/03/01
Alfa Aesar
Product number
B20148
Product name
Ethyl 2-oxo-4-phenylbutyrate, 90+%
Packaging
50g
Price
$135.65
Updated
2024/03/01
TRC
Product number
E925385
Product name
Ethyl 2-oxo-4-phenylbutyrate, 90+%
Packaging
25g
Price
$105
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0000360
Product name
ETHYL 2-OXO-4-PHENYLBUTYRATE
Purity
95.00%
Packaging
1G
Price
$128.1
Updated
2021/12/16
AK Scientific
Product number
J54157
Product name
Ethyl 2-oxo-4-phenylbutyrate
Packaging
100g
Price
$180
Updated
2021/12/16
More
Less

Ethyl 2-oxo-4-phenylbutyrate Chemical Properties,Usage,Production

synthesis

Potassium tert-butoxide (4.3 g, 38.34 mmol) was added in 1 portion to a solution of the diester (8 g, 25.56 mmol) in toluene (80 mL) at 0 °C. After being stirred at the same temperature for 30 min, the reaction mixture was kept at room temperature overnight. Water (100 mL) was added, the phases were separated, and the aqueous phase was extracted with EtOAc (3 × 100 mL). The combined organic extracts  were dried and evaporated. The residue was purifified by flflash chromatography  eluting with EtOAc:light petroleum (1:9) to give 5.6 g (78%) of the keto-ester as an orange oil.

Chemical Properties

light yellow oily liquid

Uses

Ethyl 2-oxo-4-phenylbutyrate may be used in the synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate, an important chiral precursor for angiotensin-converting enzyme (ACE) inhibitor.

General Description

Ethyl 2-oxo-4-phenylbutyrate is an aliphatic α-ketoester. Bioreduction of ethyl 2-oxo-4-phenylbutyrate is reported to yield ethyl (R)-2-hydroxy-4-phenylbutanoate. The effect of ionic liquid on the asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate by Saccharomyces cerevisiae has been reported. Asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate using a bacterial reductase is reported. Enantioselective hydrogenation of ethyl 2-oxo-4-phenylbutyrate using homogeneous Rh-diphosphine and heterogeneous Pt/Al2O3-cinchona catalysts has been reported.

Ethyl 2-oxo-4-phenylbutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

Enalapril Spirapril
More
Less

Ethyl 2-oxo-4-phenylbutyrate Suppliers

Belgium 1 Canada 4 China 190 Europe 4 France 1 Germany 5 India 23 Japan 2 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 9 United States 30 Global 272
Henan yingchuang
Tel
16650708709
Fax
qq:778660296
Email
hnyingchuang@163.com
Country
China
ProdList
3924
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1541
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.
Tel
18606289633 15862625988
Fax
0512-58813106
Email
sales@clentchem.com
Country
China
ProdList
172
Advantage
60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11578
Advantage
59
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing HuaYangZhicheng Technology Co., Ltd.
Tel
13716033033
Fax
010-56276266
Email
hanchochem@163.com
Country
China
ProdList
2960
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Chengdu JingXin Technology Co., Ltd.
Tel
028-85005297 13980656781
Fax
028-85005529
Email
jingxin73730@163.com
Country
China
ProdList
3280
Advantage
50
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
sales@chemwill.com
Country
China
ProdList
1974
Advantage
58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5904
Advantage
65
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shanghai XiZhi Chemical Co., Ltd.
Tel
021-69005855 13701817869
Fax
021-69005955
Email
xizhichem@163.com
Country
China
ProdList
3339
Advantage
55
Shanghai Pengsuo Biochemical Technology Co., Ltd.
Tel
021-59118555 13701823997
Fax
021-59119222
Email
pengsuochem@163.com
Country
China
ProdList
3300
Advantage
55
Shijiazhuang XinZhaoYang Chemical Technology Co., Ltd.
Tel
0311-69032540 13931172911
Fax
0311-69032540
Email
2636239065@qq.com
Country
China
ProdList
289
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
More
Less

View Lastest Price from Ethyl 2-oxo-4-phenylbutyrate manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
Ethyl 2-oxo-4-phenylbutyrate 64920-29-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-12-05
Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl 2-oxo-4-phenylbutyrate 64920-29-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl 2-oxo-4-phenylbutyrate 64920-29-2
Price
US $40.00-5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
15 tons
Release date
2023-09-14

64920-29-2, Ethyl 2-oxo-4-phenylbutyrate Related Search:

Ethyl 4-hydroxy-3-methoxycinnamate Triphenylphosphine 2-Phenylphenol Ethyl butyrate Ethylparaben Ethyl vanillin Ethanol Ethyl acrylate Ethyl acetate Phenylacetone PLASMIN HUMAN FIBRINOGEN Protein hydrolyzates, fibronectin Urokinase Brinase FIBRINOPEPTIDE A, HUMAN FIBRIN ethyl 4-(2,4-difluorophenyl)-2,4-dioxobutanoate

  • 4-PHENYL-2-OXOBUTYRIC ACID ETHYL ESTER
  • 2-OXO-4-PHENYLBUTANOIC ACID ETHYL ESTER
  • 2-OXO-4-PHENYLBUTYRIC ACID ETHYL ESTER
  • BENZYLPYRUVIC ACID ETHYL ESTER
  • KETO ESTER
  • ETHYL BENZYLPYRUVATE
  • ETHYL-2 OXO-4 PHENYL BUTANOATE
  • ETHYL 2-OXO-4-PHENYLBUTYRATE
  • Ethyl 2-oxo-4-phenylbutyrate (93%)
  • Ethyl 2-oxo-4-phenylbutyrate 97%
  • Benzenebutanoicacid,.alpha.-oxo-,ethylester
  • ETHYL-2-OXO-4-PHENYLBUTRATE
  • Ethyl 2-oxo-phenylbutrate (EOPB)
  • Benzenebutanoic acid, a-oxo-, ethyl ester
  • Ethyl 2-oxo-4-phenylbutyrate, 90+%
  • α-Oxobenzenebutanoic acid ethyl ester
  • α-Oxobenzenebutyric acid ethyl ester
  • Ethy 2-oxo-4-phenylbutyrate
  • Ethyl 2-oxo-4-phenylbutyrate (for ACEI)
  • Ethyl 4-phenyl-2-oxobutanoate
  • 2-oxo-4-phenylhexanoate
  • Benzylpyruvic Acid Ethyl Ester Ethyl Benzylpyruvate 2-Oxo-4-phenylbutyric Acid Ethyl Ester
  • 2 - oxo -4 - ethyl benzene
  • Ethyl 2-oxo-4-phenylbutyrate (&gt
  • Ethyl 2-oxo-4-phenylbutyrate USP/EP/BP
  • TIANFU CHEM Ethyl 2-oxo-4-phenylbutyrate
  • Ethyl α-oxobenzenebutanoate
  • Benzenebutanoic acid, α-oxo-, ethyl ester
  • Ethyl 2-oxy-butyrate
  • BEChemicalbookNZYLPYRUVICACIDETHYLESTER
  • Ethyl-2- oxyl-4-Phenyl Butyrate
  • Ethyl-2-oxo-4-pheny1Butyrate
  • 64920-29-2
  • 6490-29-2
  • C6H5CH2CH2COCOOCH2CH3
  • Building Blocks
  • Carbonyl Compounds
  • C12 to C63
  • Esters
  • Organic Building Blocks
  • C12 to C63
  • Carbonyl Compounds
  • Esters
  • Aromatics
  • Intermediates of Sertraline
  • Pharmaceutical Intermediates
  • Building Blocks
  • C12 to C63
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • (intermediate of lisinopril )
  • 1