2-[(Diphenylmethyl)thio]acetic acid

Product Name: 2-[(Diphenylmethyl)thio]acetic acid
CAS No.: 63547-22-8
Chemical Name: 2-[(Diphenylmethyl)thio]acetic acid
Synonyms: AKOS BC-179;AKOS BC-1797;ArModafinil IMpurity B;(BENZHYDRYLTHIO)ACETIC ACID;2-(benzhydrylthio)acetic acid;(Benzhydrylthio)aceticAcid>BENZHYDRYLSULFANYL ACETIC ACID;2-PHENYL METHYLTHIO ACETIC ACID;2-[(diphenylmethyl)thio]acetate;2-[(DIPHENYLMETHYL)THIO]ACETIC ACID
CBNumber: CB2211062
Molecular Formula: C15H14O2S
Formula Weight: 258.34
MOL File: 63547-22-8.mol

More

Less

2-[(Diphenylmethyl)thio]acetic acid Property

Melting point:: 127-1290C
Boiling point:: 408.6±33.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 3.68±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C15H14O2S/c16-14(17)11-18-15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H,16,17)
InChIKey: HTHFEDOFDBZPRX-UHFFFAOYSA-N
SMILES: C(O)(=O)CSC(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference: 63547-22-8(CAS DataBase Reference)

More

Less

Safety

HS Code: 2930.90.2900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B4175
Product name: (Benzhydrylthio)acetic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $111
Updated: 2025/07/31

TCI Chemical

Product number: B4175
Product name: (Benzhydrylthio)acetic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $335
Updated: 2025/07/31

TRC

Product number: D491830
Product name: 2-[(Diphenylmethyl)thio]aceticAcid
Packaging: 5g
Price: $580
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22503
Product name: 2-[(Diphenylmethyl)thio]acetic acid
Packaging: 5G
Price: $660.7
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22503
Product name: 2-[(Diphenylmethyl)thio]acetic acid
Packaging: 10g
Price: $1201.2
Updated: 2021/12/16

More

Less

2-[(Diphenylmethyl)thio]acetic acid Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Powder

Uses

Intermediate in the preparation of Modafinil

Synthesis

91-01-0

68-11-1

63547-22-8

General procedure for the synthesis of 2-[(diphenylmethyl)mercapto]acetic acid from diphenylmethanol and mercaptoacetic acid: mercaptoacetic acid (10.5 g, 7.92 mL, density = 1.325 g/mL, 0.114 mol) was added slowly and dropwise to a solution of trifluoroacetic acid (100 mL) in diphenylmethanol. During the dropwise addition, precipitate formation was observed within 30 minutes. The reaction mixture was stirred continuously for 3 hours at room temperature. Upon completion of the reaction, the precipitate was collected by filtration and washed sequentially with water (3 x 50 mL) and hexane. The crude product was purified by recrystallization from EtOAc/hexane mixed solvent to give colorless crystals of 2-[(diphenylmethyl)thio]acetic acid. Yield: 17.93 g (64% yield). Melting point: 121°C.

References

[1] Journal of Medicinal Chemistry, 1993, vol. 36, # 20, p. 2984 - 2997
[2] Tetrahedron Asymmetry, 2004, vol. 15, # 6, p. 1053 - 1058
[3] Tetrahedron Asymmetry, 2005, vol. 16, # 21, p. 3507 - 3511
[4] Patent: US7553646, 2009, B2
[5] Molecules, 2012, vol. 17, # 9, p. 10446 - 10458

2-[(Diphenylmethyl)thio]acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-[(Diphenylmethyl)thio]acetic acid Suppliers

Americas 1 Canada 1 China 129 Europe 1 Germany 2 India 31 Italy 1 Japan 1 Slovakia 1 South Korea 1 Ukraine 2 United Kingdom 7 United States 21 Global 199

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

More

Less

View Lastest Price from 2-[(Diphenylmethyl)thio]acetic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2-[(Diphenylmethyl)thio]acetic acid 63547-22-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-06

Career Henan Chemical Co

Product: 2-[(Diphenylmethyl)thio]acetic acid 63547-22-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-01-08

63547-22-8, 2-[(Diphenylmethyl)thio]acetic acidRelated Search:

Mercaptoacetic acid Calcium thioglycolate POTASSIUM THIOGLYCOLATE Ammonium thioglycolate Sodium thioglycolate Methyl thioglycolate Thiosalicylic acid Ethyl 2-(Chlorosulfonyl)acetate 2-Ethylhexyl mercaptoacetate Phenylacetic acid Acetic anhydride (METHYLTHIO)ACETIC ACID Modafinil Carboxylate-d5 Methyl Ester 2-Benzhydrylsulphinylacetic acid ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER Modafinil Carboxylate-d5 Modafinil Carboxylate Methyl Ester (Diphenylmethyl)Thio Acetic Acid Ethyl Ester

2-PHENYL METHYLTHIO ACETIC ACID

2-[(DIPHENYLMETHYL)THIO]ACETIC ACID

AKOS BC-1797

2-(Diphenylmethyl)sulfide acetic acid

BENZHYDRYLSULFANYL ACETIC ACID

(BENZHYDRYLTHIO)ACETIC ACID

AKOS BC-179

Acetic acid, [(diphenylmethyl)thio]-

2-(benzhydrylthio)acetic acid

Acetic acid, [(diphenylMethyl)thio]- (9CI)

ArModafinil IMpurity B

2-[(diphenylmethyl)thio]acetate

2-[(diphenylmethyl)sulfanyl]acetic acid

(Benzhydrylthio)aceticAcid&gt

Acetic acid, 2-[(diphenylmethyl)thio]-

Armodafinil Impurity 3/(2-benzhydryl thio)acetic acid

2-[(DiphenyI Methyl) Thio] Acetic Acid

63547-22-8

62547-22-8

C15H14O2S

Aromatics Compounds

Benzene series

Aromatics

Sulfur & Selenium Compounds