ChemicalBook > CAS DataBase List > 15(R)-PROSTAGLANDIN E1

15(R)-PROSTAGLANDIN E1

Product Name
15(R)-PROSTAGLANDIN E1
CAS No.
19313-28-1
Chemical Name
15(R)-PROSTAGLANDIN E1
Synonyms
PGE0;13,14-dihydro PGE1;Prostaglandin E0 >AlprostadilImpurity5;13,14-Dihydroprostaglandinee1;13,14-DIHYDROPROSTAGLANDIN E1;Prostaglandin E1 Impurity 5 (PGE0);90% (20% solution in ethyl acetate);13,14-Dihydro-prostaglandin E1 (PGE0);9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
CBNumber
CB2233138
Molecular Formula
C20H36O5
Formula Weight
356.5
MOL File
19313-28-1.mol
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15(R)-PROSTAGLANDIN E1 Property

Boiling point:
541.4±35.0 °C(Predicted)
Density 
1.075±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Ethyl Acetate, Methanol, Tetrahydrofuran
form 
Colorless to pale yellow oil
pka
4.77±0.10(Predicted)
Stability:
Volatile
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13610
Product name
13,14-dihydro Prostaglandin E1
Purity
≥98%
Packaging
500μg
Price
$47
Updated
2024/03/01
Cayman Chemical
Product number
13610
Product name
13,14-dihydro Prostaglandin E1
Purity
≥98%
Packaging
1mg
Price
$87
Updated
2024/03/01
Cayman Chemical
Product number
13610
Product name
13,14-dihydro Prostaglandin E1
Purity
≥98%
Packaging
5mg
Price
$360
Updated
2024/03/01
Cayman Chemical
Product number
13610
Product name
13,14-dihydro Prostaglandin E1
Purity
≥98%
Packaging
10mg
Price
$629
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
BIO0000263
Product name
13,14-DIHYDRO-PGE1
Purity
95.00%
Packaging
5MG
Price
$907.14
Updated
2021/12/16
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15(R)-PROSTAGLANDIN E1 Chemical Properties,Usage,Production

Description

13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.

Uses

Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.

Definition

ChEBI: 13,14-Dihydro PGE1 is a prostanoid.

15(R)-PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

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15(R)-PROSTAGLANDIN E1 Suppliers

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19313-28-1, 15(R)-PROSTAGLANDIN E1Related Search:

PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid 8-[(3S,4S)-4α-[(Z)-2-Pentenyl]-5-oxo-1-cyclopentene-3α-yl]octanoic acid 15-Hydroxy Lubiprostone 13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 11BETA-PROSTAGLANDIN E1 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 11-DEOXY PROSTAGLANDIN E1 13,14-DIHYDRO PROSTAGLANDIN E1-D4 13,14-DIHYDRO-19(R)-HYDROXY PROSTAGLANDIN E1 13,14-DIHYDROPROSTAGLANDIN E1 13,14-Dihydroprostaglandin F2α 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 15-keto-13,14-dihydroprostaglandin A2 15-keto-13,14-dihydroprostaglandin E2-thyroglobulin conjugate 2,3-dinor-6,15-diketo-13,14-dihydroprostaglandin F1alpha 13,14-dihydroprostaglandin E2

  • 9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID
  • 13,14-DIHYDROPROSTAGLANDIN E1
  • PGE0
  • 13,14-Dihydroprostaglandinee1
  • 13,14-dihydro PGE1
  • 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid
  • (11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid
  • Prostan-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,15S)-
  • 13,14-Dihydro-prostaglandin E1 (PGE0)
  • 9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
  • Prostaglandin E0 &gt
  • 90% (20% solution in ethyl acetate)
  • Prostaglandin E1 Impurity 5 (PGE0)
  • Prostan-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,15S)-
  • Prostaglandin E0 >90% (20% solution in ethyl acetate)
  • AlprostadilImpurity5
  • Alprostadil (Prostaglandin E1) Impurity 5 (PGE0)
  • Alprostadil (prostaglandin E1) Impurity 12 (PGE0)
  • 19313-28-1