15(R)-PROSTAGLANDIN E1

Product Name: 15(R)-PROSTAGLANDIN E1
CAS No.: 19313-28-1
Chemical Name: 15(R)-PROSTAGLANDIN E1
Synonyms: PGE0;13,14-dihydro PGE1;Prostaglandin E0 >AlprostadilImpurity5;13,14-Dihydroprostaglandinee1;13,14-DIHYDROPROSTAGLANDIN E1;Prostaglandin E1 Impurity 5 (PGE0);90% (20% solution in ethyl acetate);13,14-Dihydro-prostaglandin E1 (PGE0);9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
CBNumber: CB2233138
Molecular Formula: C20H36O5
Formula Weight: 356.5
MOL File: 19313-28-1.mol

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15(R)-PROSTAGLANDIN E1 Property

Boiling point:: 541.4±35.0 °C(Predicted)
Density: 1.075±0.06 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: Ethyl Acetate, Methanol, Tetrahydrofuran
form: Colorless to pale yellow oil
pka: 4.77±0.10(Predicted)
Stability:: Volatile

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13610
Product name: 13,14-dihydro Prostaglandin E1
Purity: ≥98%
Packaging: 500μg
Price: $47
Updated: 2024/03/01

Cayman Chemical

Product number: 13610
Product name: 13,14-dihydro Prostaglandin E1
Purity: ≥98%
Packaging: 1mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 13610
Product name: 13,14-dihydro Prostaglandin E1
Purity: ≥98%
Packaging: 5mg
Price: $360
Updated: 2024/03/01

Cayman Chemical

Product number: 13610
Product name: 13,14-dihydro Prostaglandin E1
Purity: ≥98%
Packaging: 10mg
Price: $629
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: BIO0000263
Product name: 13,14-DIHYDRO-PGE1
Purity: 95.00%
Packaging: 5MG
Price: $907.14
Updated: 2021/12/16

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15(R)-PROSTAGLANDIN E1 Chemical Properties,Usage,Production

Description

13,14-dihydro Prostaglandin E₁ (13,14-dihydro PGE₁) is a biologically active metabolite of PGE₁ with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC₅₀ values of 31 and 21 nM, respectively. 13,14-dihydro PGE₁ is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE₁ which has an IC₅₀ value of 40 nM. Also, 13,14-dihydro PGE₁ was shown to activate adenylate cyclase in NCB-20 hybrid cells with a K_act value of 668 nM.

Uses

Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.

Definition

ChEBI: 13,14-Dihydro PGE1 is a prostanoid.

15(R)-PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

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19313-28-1, 15(R)-PROSTAGLANDIN E1Related Search:

PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid 8-[(3S,4S)-4α-[(Z)-2-Pentenyl]-5-oxo-1-cyclopentene-3α-yl]octanoic acid 15-Hydroxy Lubiprostone 13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 11BETA-PROSTAGLANDIN E1 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 11-DEOXY PROSTAGLANDIN E1 13,14-DIHYDRO PROSTAGLANDIN E1-D4 13,14-DIHYDRO-19(R)-HYDROXY PROSTAGLANDIN E1 13,14-DIHYDROPROSTAGLANDIN E1 13,14-Dihydroprostaglandin F2α 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 15-keto-13,14-dihydroprostaglandin A2 15-keto-13,14-dihydroprostaglandin E2-thyroglobulin conjugate 2,3-dinor-6,15-diketo-13,14-dihydroprostaglandin F1alpha 13,14-dihydroprostaglandin E2

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID

13,14-DIHYDROPROSTAGLANDIN E1

PGE0

13,14-Dihydroprostaglandinee1

13,14-dihydro PGE1

7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid

(11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid

Prostan-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,15S)-

13,14-Dihydro-prostaglandin E1 (PGE0)

9-oxo-11α,15S-dihydroxy-prostan-1-oic acid

Prostaglandin E0 &gt

90% (20% solution in ethyl acetate)

Prostaglandin E1 Impurity 5 (PGE0)

Prostan-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,15S)-

Prostaglandin E0 >90% (20% solution in ethyl acetate)

AlprostadilImpurity5

Alprostadil (Prostaglandin E1) Impurity 5 (PGE0)

19313-28-1