ChemicalBook > CAS DataBase List > Ethyl 6-chloronicotinate

Ethyl 6-chloronicotinate

Product Name
Ethyl 6-chloronicotinate
CAS No.
49608-01-7
Chemical Name
Ethyl 6-chloronicotinate
Synonyms
Ethyl 6-chloropyridine-3-carboxylate;Ethyl 6-chloronicoti;6-chloro ethyl sMoke;6-Chloronictinic Acid;Ethyl 6-chloronicotite;thyl 6-chloronicotinate;ETHYL 6-CHLORONICOTINATE;Ethyl6-Chloronicotinate>Ethyl6-chloronicotinate,97%;Ethyl 6-Chloro-3-nicotinate
CBNumber
CB2236371
Molecular Formula
C8H8ClNO2
Formula Weight
185.61
MOL File
49608-01-7.mol
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Ethyl 6-chloronicotinate Property

Melting point:
26-30 °C(lit.)
Boiling point:
98 °C
Density 
1.245±0.06 g/cm3(Predicted)
refractive index 
1.522
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-1.95±0.10(Predicted)
color 
Colourless to Off-White Oil
BRN 
4742175
InChIKey
ILDJJTQWIZLGPO-UHFFFAOYSA-N
CAS DataBase Reference
49608-01-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
531197
Product name
Ethyl 6-chloropyridine-3-carboxylate
Purity
97%
Packaging
25g
Price
$41.6
Updated
2024/03/01
TCI Chemical
Product number
E0852
Product name
Ethyl 6-Chloronicotinate
Purity
>97.0%(GC)
Packaging
5g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
E0852
Product name
Ethyl 6-Chloronicotinate
Purity
>97.0%(GC)
Packaging
25g
Price
$92
Updated
2024/03/01
Alfa Aesar
Product number
A14723
Product name
Ethyl 6-chloronicotinate, 97%
Packaging
5g
Price
$33.65
Updated
2024/03/01
Alfa Aesar
Product number
A14723
Product name
Ethyl 6-chloronicotinate, 97%
Packaging
25g
Price
$106.65
Updated
2024/03/01
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Ethyl 6-chloronicotinate Chemical Properties,Usage,Production

Chemical Properties

White to light yellow solid or colorless to yellow liquid

Uses

Ethyl 6-chloropyridine-3-carboxylate (Ethyl 6-chloronicotinate) may be used in the preparation of ethyl 5-{[5-(1H-benzimidazol-2-yl)pyridin-2-yl]ethynyl}pyridine-2-carboxylate by reacting with 2-[6-(ethynyl)pyridin-3-yl]-1H-benzimidazole under microwave irradiation.

Uses

Ethyl 6-chloronicotinate is a nicotinic acid derivative used in the preparation of potent H3 receptor antagonists.

General Description

Ethyl 6-chloropyridine-3-carboxylate (Ethyl-6-chloronicotinate, E-6-ClN) undergoes direct amidation on reacting with benzylamine in the presence lanthanum trifluoromethanesulfonate La(OTf)3. The structural and physicochemical properties of E-6-ClN have been investigated based on its spectroscopic data, time-dependent density functional theory and density of state diagrams.

Ethyl 6-chloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

[6-(1-PYRROLIDINYL)-3-PYRIDINYL]METHANOL 6-MORPHOLINONICOTINOHYDRAZIDE 6-MORPHOLINONICOTINONITRILE (6-MORPHOLINO-3-PYRIDINYL)METHANOL
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Ethyl 6-chloronicotinate Suppliers

Americas 1 Belgium 1 Canada 1 China 203 Europe 1 France 2 Germany 6 India 25 Italy 1 Japan 2 Switzerland 3 Ukraine 1 United Kingdom 12 United States 36 Global 295
Pure Chemistry Scientific Inc.
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View Lastest Price from Ethyl 6-chloronicotinate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl 6-chloronicotinate 49608-01-7
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-05-25
Hebei Mojin Biotechnology Co., Ltd
Product
Ethyl 6-chloronicotinate 49608-01-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-01
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl 6-chloronicotinate 49608-01-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

49608-01-7, Ethyl 6-chloronicotinateRelated Search:

Ethyl cyanoacetate RESMETHRIN Ethyl acrylate Trinexapac-ethyl Ethyl formate Tris(trimethylsilyl)phosphate Ethylparaben Ethyl 2-chloroacetoacetate Ethyl chloroacetate Ethyl propiolate Ethyl isonicotinate ISOXADIFEN-ETHYL Ethanol Methyl acrylate Ethyl 5-bromonicotinate Ethyl nicotinate Ethyl acetate Ethyl chloroformate

  • 3-Pyridinecarboxylic acid, 6-chloro-, ethyl ester
  • ETHYL 6-CHLORONICOTINATE[FOR TAZAROTENE]
  • Ethyl 6-chloropyridine-3-carboxylate
  • ETHYL 2-CHLOROPYRIDINE-5-CARBOXYLATE
  • Ethyl 6-chloronicoti
  • 2-Chloro-5-pyridinecarboxylicacid ethylester
  • Ethyl6-chloronicotinate,97%
  • Ethyl 2-chloropyridine-3-carboxylate, 6-Chloronicotinic acid ethyl ester
  • Ethyl 6-chloropyridine-3-carboxylate ,98%
  • 6-Chloro-3-pyridinecarboxylic acid ethyl ester
  • Ethyl 6-chloro-3-pyridinecarboxylate
  • 6-chloro ethyl sMoke
  • Ethyl 6-chloropyridine-3-carboxylate, 2-Chloro-5-(ethoxycarbonyl)pyridine
  • 2-Chloropyridine-5-carboxylic Acid Ethyl Ester
  • Ethyl 2-chloro-5-pyridinecarboxylate
  • Ethyl 6-Chloro-3-nicotinate
  • 6-Chloronicotinic Acid Ethyl Ester Ethyl 2-Chloro-5-pyridinecarboxylate 2-Chloro-5-pyridinecarboxylic Acid Ethyl Ester
  • thyl 6-chloronicotinate
  • Ethyl 6-chloropyridine-3-carboxylate 97%
  • Ethyl 6-chloronicotite
  • Ethyl - 6 chloronicotinate for synthesis
  • ETHYL 6-CHLORONICOTINATE
  • 6-CHLORONICOTINIC ACID ETHYL ESTER
  • 6-Chloro Nitotinic acid Ethyl ester
  • 6-Chloronicotinic acid ethyl ester (Ethyl-6-Chloronicotinate)
  • Ethyl6-Chloronicotinate&gt
  • 6-Chloronictinic acid ethyl ester
  • Ethyl 6-chloronicotinate ISO 9001：2015 REACH
  • 6-Chloronictinic Acid
  • 3-Pyridinecarboxylic acid, 6-chloro-, ethyl ester (9CI, ACI)
  • 6-chloro-3-Pyridinecarboxylic acid ethyl ester (9CI ACI)
  • 49608-01-7
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines
  • Building Blocks
  • C7 to C18
  • C8 to C9
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Heterocycle-Pyridine series
  • carboxylic ester| alkyl chloride
  • Esters
  • Pyridines