ChemicalBook > CAS DataBase List > (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester

Product Name
(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
CAS No.
124655-09-0
Chemical Name
(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
Synonyms
Rosuvastatin P-2;(4R-Cis)-6-Hydroxyme;Atorvastatin calcium-12;Rosuvastatin side-chains;Pitavastatin Impurity 63;ROSVASTATIN INTERMEDIATES;idene-3,5-dihydroxyhexanoate;rosuvastatin intermediatesC-5;Rosuvastatin Calcium Impurity 6;Atorvastatin calcium impurity 20
CBNumber
CB2238335
Molecular Formula
C13H24O5
Formula Weight
260.33
MOL File
124655-09-0.mol
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(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Property

Boiling point:
331°C
Density 
1.030
refractive index 
1.4500-1.4540
Flash point:
113°C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
14.25±0.10(Predicted)
color 
Pale Yellow to Brown
InChIKey
CFRUAOXMCVQMFP-ZJUUUORDSA-N
CAS DataBase Reference
124655-09-0(CAS DataBase Reference)
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Safety

HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4214
Product name
tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Purity
>98.0%(GC)
Packaging
5g
Price
$114
Updated
2024/03/01
TCI Chemical
Product number
B4214
Product name
tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Purity
>98.0%(GC)
Packaging
25g
Price
$396
Updated
2024/03/01
TRC
Product number
H946660
Product name
(4R,6S)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster
Packaging
1g
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-W019118
Product name
tert-Butyl(3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate
Packaging
10g
Price
$79
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB05616
Product name
tert-Butyl(3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate
Packaging
5G
Price
$95
Updated
2021/12/16
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(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

A useful synthetic intermediate in the preparation of Rosuvastatin (R700500) and its derivatives

Uses

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester is a useful synthetic intermediate.

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Suppliers

Americas 1 Canada 2 China 188 Europe 3 France 2 Germany 1 India 26 Japan 2 South Korea 1 United Kingdom 8 United States 23 Global 257
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Kaneka Corporation
Tel
--
Fax
--
Email
finechem@kaneka.co.jp
Country
Japan
ProdList
112
Advantage
81
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View Lastest Price from (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester 124655-09-0
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14
Hebei Mojin Biotechnology Co., Ltd
Product
(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester 124655-09-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-01-12
Hangzhou ICH Biofarm Co., Ltd
Product
(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester 124655-09-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200
Release date
2023-07-07

124655-09-0, (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl esterRelated Search:

tert-Butyl acetate Methyl 2,2-dimethylphenylacetate Tris(hydroxymethyl)nitromethane tert-Butyl chloroacetate tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate 1,4-Dioxane Dimethyl sulfate Dimethyl ether Dacthal Dimethylbenzylcarbinyl acetate ETHANE N,N-Dimethylformamide Dimethyl sulfoxide DL-sec-Butyl acetate Ethyl 2-(Chlorosulfonyl)acetate Dimethyl fumarate Butyl acetate tert-Butyl peroxyacetate

  • D-6 (4R-Cis)-6-HydroxyMethyl-2,2-DiMethyl-1,3-Dioxane-4-AceticAcid,1,1-DiMethylthylEster
  • <i>tert</i>-Butyl (4<i>R</i>,6<i>S</i>)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • rosuvastatin intermediatesC-5
  • T-BUTYL-(3R,5S)-6-HYDROXY 3,5-O-ISOPROPYLIDENE 3,5-DIHYDROXYHEXANOATE
  • TERT-BUTYL [(4R,6S)-6-(HYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-YL] ACETATE
  • TERT-BUTYL (3R,5S)-6-HYDROXY 3,5-O-ISOPROPYLIDENE-3,5-DIHYDROXYHEXANOATE
  • 2-[(4r,6s)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-butyl ester
  • (6S-Hydroxymethyl-2,2-dimethyl-[1,3]dioxan-4R-yl)acetic acid tert-butyl ester
  • ((4r,6s)-6-hydroxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
  • (4R-CIS)-6-HYDROXYMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID 1,1-DIMETHYLETHYL ESTER
  • (4R-CIS)-6-HYDROXYMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID, T-BUTYL ESTER
  • Rosuvastatin side-chains
  • ROSVASTATIN INTERMEDIATES
  • TERT-BUTYL[(4R,6R)-6-HYDROXYMETHYL-1,3-DIOXAN-4-YL]ACETATE
  • T-BUTYL-(3R,5S)-6-HYDROXY-3,5-O-ISOPROPYLIDENE
  • 4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl est
  • (4R-CIS)-6-HYDROXYMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETI ACID,1,1-DIMETHYLETHYL ESTER
  • (4R-Cis)-6-Hydroxyme
  • 2,4-Dideoxy-3,5-O-(1-Methylethylidene)-D-erythro-hexonic Acid 1,1-DiMethylethyl Ester
  • tert-Butyl 2-((4R,6S)-6-(hydroxyMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate
  • 4R-Cis)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic acid 1,1-diMethylethyl ester (D6)
  • (4R,6S)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid, 1,1-DiMethylethyl Ester
  • (4R-Cis)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic acid,1,1-diMenthylethyl ester
  • Rosuvastatin calciuM interMediate C-2
  • D-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-Methylethylidene)-, 1,1-diMethylethyl ester
  • tert-Butyl (4R,6S)-6-(HydroxyMethyl)-2,2-diMethyl-1,3-dioxane-4-acetate
  • Atorvastatin calcium-12
  • 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]-3,3-dimethylbutanoate
  • Atorvastatin Calcium Hydrate impurity 20
  • Rosuvastatin Calcium Impurity 6
  • Rosuvastatin P-2
  • tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate &gt
  • Pitavastatin Impurity 63
  • (3R,5S)-6-hydroxy-3,5-O-isopropyL
  • idene-3,5-dihydroxyhexanoate
  • (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
  • T-butyl-(3R,5S)-6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxy...
  • D-6 (4R-Cis)-6-Hydroxymethyl -2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Dimethyethyl Ester
  • Atorvastatin calcium impurity 20
  • Rosuvastatin Impurity 1（Pitavastatin Impurity 63）
  • Tert-Butyl(4R,6S)-2-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate
  • tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate, ≥ 98.0%
  • tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2
  • 124655-09-0
  • C13H24O5
  • C13H24O4
  • chiral
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals