Ethyl bromodifluoroacetate

Product Name: Ethyl bromodifluoroacetate
CAS No.: 667-27-6
Chemical Name: Ethyl bromodifluoroacetate
Synonyms: 2-broMo-2,2-difluoroacetate;EBDA;2-Bromo-2,2-difluoroacetic acid ethyl ester;EBFA;bromodifL;Ethyl bromodifluoroa;Ethylbromdifluoracetat;Twoethyl broMidefluoride;ETHYL BROMODIFLUOROACETATE;difluorobromo ethyl acetate
CBNumber: CB2238865
Molecular Formula: C4H5BrF2O2
Formula Weight: 202.98
MOL File: 667-27-6.mol

More

Less

Ethyl bromodifluoroacetate Property

Boiling point:: 112 °C/700 mmHg (lit.)
Density: 1.583 g/mL at 25 °C (lit.)
refractive index: n20/D 1.387(lit.)
Flash point:: 70 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Soluble in most organic solvents.
form: Liquid
color: Clear colorless to slightly yellow
Specific Gravity: 1.583
BRN: 1906095
InChI: InChI=1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
InChIKey: IRSJDVYTJUCXRV-UHFFFAOYSA-N
SMILES: C(OCC)(=O)C(Br)(F)F
CAS DataBase Reference: 667-27-6(CAS DataBase Reference)
NIST Chemistry Reference: Ethyl bromodifluoroacetate(667-27-6)

More

Less

Safety

Hazard Codes: C,F,Xi
Risk Statements: 10-34-36
Safety Statements: 26-36/37/39-45-16-27
RIDADR: UN 2924 3/PG 2
WGK Germany: 3
Hazard Note: Irritant/Flammable
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29159000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 295795
Product name: Ethyl bromodifluoroacetate
Purity: 98%
Packaging: 5g
Price: $72.2
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 5g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 25g
Price: $53
Updated: 2024/03/01

Alfa Aesar

Product number: B20461
Product name: Ethyl bromodifluoroacetate, 97%
Packaging: 5g
Price: $65.65
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 250g
Price: $306
Updated: 2024/03/01

More

Less

Ethyl bromodifluoroacetate Chemical Properties,Usage,Production

Description

Ethyl bromodifluoroacetate, a clear to yellow liquid, is an ester of bromodifluoroacetic acid and ethyl alcohol. It is an ester that can be used to introduce the CF2 group when synthesizing chemical compounds. Ethyl bromdifluoroacetate is considered to be a good compound in the generation of compounds and for testing with other organic compounds like lactones, imines, and other amino acids.

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Ethyl bromodifluoroacetate, is used for the treatment of the Reformat sky reagent with aldehydes and ketones affords 2,2-difluoro-3-hydroxy esters. It is also used in the analysis of reagent purity through IR, NMR.

Uses

Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. A Cu-catalyzed regioselective bromodifluoroacetylation of alkenes, using ethyl bromodifluoroacetate (BrCF2CO2Et) as a difluoroacetylating reagent.

Uses

Ethyl bromodifluoroacetate is usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.

Preparation

Difluorobromoacetonitrile is taken as a raw material, and prepared through a one-pot method and subjected to alcoholysis and esterification in ethanol aqueous solution to obtain ethyl bromodifluoroacetate.Reaction equation is:
BrF2CCN→BrF2CCOOH→BrF2CCOOC2H5

Ethyl bromodifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Ethyl bromodifluoroacetate Suppliers

Americas 1 Belgium 4 Canada 2 China 362 China Hong Kong 1 Europe 6 France 2 Germany 5 India 31 Ireland 1 Italy 1 Japan 4 Russia 1 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 17 United States 48 Global 490

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

TCI Chemicals (India) Pvt. Ltd.

Tel: --
Fax: --
Email: sales-in@tcichemicals.com
Country: India
ProdList: 6768
Advantage: 58

SRF LIMITED

Tel: --
Fax: --
Email: info@srf.com
Country: India
ProdList: 33
Advantage: 58

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

S M Chem Associates

Tel: --
Fax: --
Country: India
ProdList: 36
Advantage: 58

ChemOrbit International

Tel: --
Fax: --
Email: 2014@gmail.com
Country: India
ProdList: 264
Advantage: 58

SR Global Source

Tel: --
Fax: --
Email: info@srglobalsources.in
Country: India
ProdList: 6
Advantage: 58

Kkyemistry (india) Pvt., Ltd.

Tel: --
Fax: --
Email: marketing@kyemistryindia.com
Country: India
ProdList: 163
Advantage: 58

Gujarat Fluorochemicals Limited (GFL)

Tel: --
Fax: --
Email: contact@gfl.co.in
Country: India
ProdList: 11
Advantage: 58

VASIN BIO LIFE SCIENCES PVT LTD

Tel: --
Fax: --
Email: info@vasinbio.com
Country: India
ProdList: 2092
Advantage: 58

SM Chem Associates

Tel: --
Fax: --
Email: sastry@smchemassociates.com
Country: India
ProdList: 84
Advantage: 58

SRF Limited (Pharma Division)

Tel: --
Fax: --
Country: India
ProdList: 15
Advantage: 58

Spectrochem Private Limited

Tel: --
Fax: --
Country: India
ProdList: 1055
Advantage: 58

Vyas Bio Life Sciences Pvt. Ltd

Tel: --
Fax: --
Country: India
ProdList: 1213
Advantage: 58

ASM Organics

Tel: --
Fax: --
Country: India
ProdList: 1185
Advantage: 58

Bizten Impex Private Limited.

Tel: --
Fax: --
Country: India
ProdList: 109
Advantage: 58

Vihasibio Sciences Private Limited

Tel: --
Fax: --
Country: India
ProdList: 391
Advantage: 58

Shivam Pharma Chemicals

Tel: --
Fax: --
Email: info@shivampharma.com
Country: India
ProdList: 656
Advantage: 58

Oceanic Pharmachem Pvt. Ltd.

Tel: --
Fax: --
Email: info@oceanicpharmachem.com
Country: India
ProdList: 2005
Advantage: 58

Bizten Impex Private Limited

Tel: --
Fax: --
Country: India
ProdList: 71
Advantage: 58

Sai Quest Syn. Ltd

Tel: --
Fax: --
Country: India
ProdList: 268
Advantage: 58

Anand Agencies

Tel: --
Fax: --
Email: en@gmail.com
Country: India
ProdList: 2332
Advantage: 58

Avra Synthesis Pvt Ltd

Tel: --
Fax: --
Email: info@avrasynthesis.com
Country: India
ProdList: 1603
Advantage: 30

ARCHERCHEM

Tel: --
Fax: --
Email: archerchem@vsnl.net
Country: India
ProdList: 86
Advantage: 54

Meru Chem Pvt. Ltd.

Tel: --
Fax: --
Email: meruchempltd@gmail.com
Country: India
ProdList: 174
Advantage: 58

Gujarat Fluorochemicals Limited

Tel: --
Fax: --
Country: India
ProdList: 27
Advantage: 58

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

More

Less

View Lastest Price from Ethyl bromodifluoroacetate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.%
Supply Ability: 10 ton
Release date: 2024-08-23

Career Henan Chemical Co

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-21

667-27-6, Ethyl bromodifluoroacetateRelated Search:

Difluoroacetic acid Ethyl difluoroacetate BROMODIFLUOROACETIC ACID METHYL BROMODIFLUOROACETATE Cuprous iodide Sulfuryl chloride Hydrazine sulfate Sodium ascorbate METHYL DIFLUOROACETATE Sodium chlorodifluoroacetate Diethyl 2,2-difluoromalonate Chlorodifluoroacetic acid ethyl ester 2-(2-Aminoethoxy)ethanol Bromoacetic acid Ethyl fluoroacetate Ethyl bromofluoroacetate Ethyl bromodifluoroacetate Ethyl bromoacetate

ETHYL BROMODIFLUOROACETATE

BROMODIFLUOROACETIC ACID ETHYL ESTER

2-Bromo-2,2-difluoroacetic acid ethyl ester

Difluorobromoacetic acid ethyl ester

Ethyl 2,2-Difluoro-2-Bromoac

Ethyl bromodifluoroa

2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane

Ethyl broModifluoroacetate, 98% 5GR

Ethylbromdifluoracetat

2-broMo-2,2-difluoroacetate

2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane, Bromo(difluoro)acetic acid ethyl ester

Twoethyl broMidefluoride

Ethyl broMoacetatetwo fluorine

Acetic acid, bromodifluoro-, ethyl ester

2,2-difluoro-2-bromoacetate ethyl

Ethyl bromodifluoroacetate 98%

difluorobromo ethyl acetate

Ethylbromodifluoroacetate98%

Acetic acid, 2-bromo-2,2-difluoro-, ethyl ester

Ethyl 2,2-difluoro-2-bromoacetate

Ethyl Bromodifluoroacetate &gt

Ethyl Bromodifluoroacetate,99%

bromodifL

TIANFU CHEM---Ethyl bromodifluoroacetate

EBDA

Ethyl bromoacetate difluoro

EBFA

667-27-6

C4H5BrF2O2

BrCF2COOCH2CH3

BrCF2CO2CH2CH3

Esters

Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds

Organic Building Blocks

Building Blocks

C2 to C5

Carbonyl Compounds

Fluorinated Building Blocks

Alkyl Fluorinated Building Blocks

Building Blocks

C2 to C5

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

C2 to C5

Carbonyl Compounds

Esters

API intermediates

Fluorinated Building Blocks

Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds

Synthetic Organic Chemistry

Fluoro series

Pharmaceutical Intermediates

Fluoro-containing compounds