Difluoroacetic acid

Product Name: Difluoroacetic acid
CAS No.: 381-73-7
Chemical Name: Difluoroacetic acid
Synonyms: 2,2-DIFLUOROACETIC ACID;DIFLUOROACETATE;ifluoroaceticaci;difluoro-aceticaci;VITAS-BB TBB000649;DIFLUOROACETIC ACID;Difluoroaceticacid98%;Acetic acid, difluoro-;1,1-DIFLUOROACETIC ACID;Twotrifluoroacetic acid
CBNumber: CB2700577
Molecular Formula: C2H2F2O2
Formula Weight: 96.03
MOL File: 381-73-7.mol

More

Less

Difluoroacetic acid Property

Melting point:: -1 °C (lit.)
Boiling point:: 132-134 °C (lit.)
Density: 1.526 g/mL at 25 °C (lit.)
vapor pressure: 11.7hPa at 25℃
refractive index: n20/D 1.344(lit.)
Flash point:: 174 °F
storage temp.: 2-8°C
solubility: 540.54g/L in organic solvents at 20 ℃
form: Liquid
pka: pK1:1.33 (25°C)
color: Clear colorless to light brown
Specific Gravity: 1.527 (20℃)
Water Solubility: 1000g/L at 37℃
BRN: 1098588
InChIKey: PBWZKZYHONABLN-UHFFFAOYSA-N
LogP: 0.601 at 37℃
CAS DataBase Reference: 381-73-7(CAS DataBase Reference)
NIST Chemistry Reference: Difluoroacetic acid(381-73-7)
EPA Substance Registry System: Acetic acid, difluoro- (381-73-7)

More

Less

Safety

Hazard Codes: C
Risk Statements: 34-35
Safety Statements: 26-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
RTECS: AG9900000
Hazard Note: Corrosive
TSCA: T
HazardClass: 8
PackingGroup: II
HS Code: 29159080

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H332Harmful if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 142859
Product name: Difluoroacetic acid
Purity: 98%
Packaging: 5g
Price: $78.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 142859
Product name: Difluoroacetic acid
Purity: 98%
Packaging: 25g
Price: $191
Updated: 2024/03/01

Sigma-Aldrich

Product number: 00922
Product name: Difluoroacetic acid
Purity: for LC-MS LiChropur?, ≥97.5% (GC)
Packaging: 10X1ML
Price: $252
Updated: 2022/05/15

Sigma-Aldrich

Product number: 00922
Product name: Difluoroacetic acid
Purity: for LC-MS LiChropur?, ≥97.5% (GC)
Packaging: 50ML
Price: $802
Updated: 2022/05/15

TCI Chemical

Product number: D1423
Product name: Difluoroacetic Acid
Purity: >97.0%(T)
Packaging: 5g
Price: $50
Updated: 2024/03/01

More

Less

Difluoroacetic acid Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light brown liquid

Uses

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by fluorines.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the acid by distilling over P2O5. The acid chloride is a fuming liquid b 25o/atm, and the amide has b 108.6o/35mm, m 52o (from *C6H6), and the anilide has b 90o/1mm, 114o/5mm, m 58o [Henne & Pelley J Am Chem Soc 74 1426 1952, Coffman et al. J Org Chem 14 749 1949, NMR: Meyer et al. J Am Chem Soc 75 4567 1953, pK: Wegscheider Z Phys Chem 69 614 1909]. [Beilstein 2 IV 455.]

Difluoroacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Difluoroacetic acid Suppliers

Americas 1 Belgium 2 Brazil 1 CHINA 247 Europe 4 France 1 Germany 5 India 17 Ireland 1 Japan 7 Jordan 1 Russia 3 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 17 United States 36 Global 350

Shangfluoro

Tel: 021-021-65170832 13331983812
Email: qinba_2@163.com
Country: China
ProdList: 301
Advantage: 58

Shandong Carbon Spring New Materials Co., Ltd.

Tel: 13658618215
Email: 308410472@qq.com
Country: China
ProdList: 54
Advantage: 58

BTC Pharmaceutical CO. Ltd

Tel: 0513-0513-68015-397-397 18796027131
Fax: 0513-68015394
Email: sales14@btcpharm.com
Country: China
ProdList: 666
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40240
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1998
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

More

Less

View Lastest Price from Difluoroacetic acid manufacturers

Hebei Guanlang Biotechnology Co., Ltd.

Product: Difluoroacetic acid 381-73-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2023-03-07

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Difluoroacetic acid 381-73-7
Price: US $90.00-900.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-08

Hefei TNJ Chemical Industry Co.,Ltd.

Product: Difluoroacetic Acid 381-73-7
Price: US $0.00/L
Min. Order: 200L
Purity: 99%
Supply Ability: 1000MT
Release date: 2019-03-08

381-73-7, Difluoroacetic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate 2-Bromo-2,2-difluoroacetic acid ethyl ester Glycine Folic acid Trifluoroacetic acid Trifluoroacetic anhydride DIFLUOROACETIC ACID ETHYL ESTER,ETHYL DIFLUOROACETIC ACID Fluroxypyr DIFLUOROACETIC ACID METHYL ESTER,α,2-Difluoroacetic acid methyl ester Ethyl trifluoroacetate Citric acid Chlorodifluoroacetic acid ethyl ester Sodium chlorodifluoroacetate Diethyl 2,2-difluoromalonate Ascoric Acid DIFLUOROACETIC ACID ANHYDRIDE TRIMETHYLSILYL TRIFLUOROACETATE THALLIUM(III) TRIFLUOROACETATE

2,2-DIFLUOROACETIC ACID

1,1-DIFLUOROACETIC ACID

VITAS-BB TBB000649

DIFLUOROACETIC ACID

Acetic acid, difluoro-

difluoro-aceticaci

DIFLUOROACETATE

Difluoroaceticacid98%

Difluoroacetic acid, 98% 10ML

Difluoroacetic acid, 98% 2.5ML

2,2-Difluoroethanoic acid

Twotrifluoroacetic acid

Aceticacid, 2,2-difluoro-

Difluoroacetic acid, 97%+

Difluoroacetic Acid &gt

ifluoroaceticaci

381-73-7

7381-73-7

F2CHCO2H

F2CHCOOH

CHF2COOH

C2H2F2O2

CARBOXYLIC ACID

Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds

Fluorinated Building Blocks

Synthetic Reagents

Organic Acids

Pharmaceutical Intermediates

Small molecule

Organic Fluorides

Fluorinated Building Blocks

Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds

Synthetic Organic Chemistry

Chemical Synthesis

Organic Acids

Synthetic Reagents