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Ethyl difluoroacetate

Product Name
Ethyl difluoroacetate
CAS No.
454-31-9
Chemical Name
Ethyl difluoroacetate
Synonyms
Ethyl difluoroacetic;DIFLUOROACETIC ACID ETHYL ESTER;uroacetate;AKOS B020251;ethyldifluoracetat;ART-CHEM-BB B020251;Ethyldifluorocetate;Ethyl Difluroacetate;ETHYL DIFLUOROACETATE;Difluoroacetate(DFAE)
CBNumber
CB3252699
Molecular Formula
C4H6F2O2
Formula Weight
124.09
MOL File
454-31-9.mol
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Ethyl difluoroacetate Property

Boiling point:
99.2 °C (lit.)
Density 
1.18 g/mL at 25 °C (lit.)
vapor pressure 
30.03-200.2hPa at 20.03-56.98℃
refractive index 
1.3465-1.3485
Flash point:
25 °C
storage temp. 
2-8°C
solubility 
DMSO (Sparingly), Methanol (Sparingly)
form 
Liquid
Specific Gravity
1.242
color 
Clear colorless
Water Solubility 
Slightly soluble in water
BRN 
1748597
InChI
1S/C4H6F2O2/c1-2-8-4(7)3(5)6/h3H,2H2,1H3
InChIKey
GZKHDVAKKLTJPO-UHFFFAOYSA-N
SMILES
CCOC(=O)C(F)F
LogP
0.87 at 25℃
CAS DataBase Reference
454-31-9(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, difluoro-, ethyl ester(454-31-9)
EPA Substance Registry System
Acetic acid, difluoro-, ethyl ester (454-31-9)
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Safety

Hazard Codes 
C,F,T,Xi
Risk Statements 
34-10
Safety Statements 
45-36/37/39-26-16-27
RIDADR 
1992
WGK Germany 
3
Hazard Note 
Flammable
TSCA 
TSCA listed
HazardClass 
3
PackingGroup 
III
HS Code 
29159000
Storage Class
3 - Flammable liquids
Hazard Classifications
Flam. Liq. 3
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
287628
Product name
Ethyl difluoroacetate
Purity
97%
Packaging
5g
Price
$42.3
Updated
2026/03/19
Sigma-Aldrich
Product number
287628
Product name
Ethyl difluoroacetate
Purity
97%
Packaging
25g
Price
$62
Updated
2026/03/19
TCI Chemical
Product number
D2498
Product name
Ethyl Difluoroacetate
Purity
>98.0%(GC)
Packaging
5g
Price
$53
Updated
2026/03/19
TCI Chemical
Product number
D2498
Product name
Ethyl Difluoroacetate
Purity
>98.0%(GC)
Packaging
25g
Price
$131
Updated
2026/03/19
TRC
Product number
E916603
Product name
Ethyl Difluoroacetate
Packaging
50g
Price
$80
Updated
2021/12/16
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Ethyl difluoroacetate Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Ethyl difluoroacetate is used in pharmaceutical intermediates, acrylization oxidation and halogenating reaction of catalyst. Also ethyl difluoroacetate is used in preparing pyrrazolo-pyrimidine derivatives.

General Description

Ethyl difluoroacetate was degraded to difluoroacetic acid by the strains of Actinobacteria.

Ethyl difluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl difluoroacetate Suppliers

HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD
Tel
571-89189769 15168342188
Fax
0571-86205065
Country
China
ProdList
229
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Shanghai Yihe Biological Technology Co., Ltd.
Tel
021-68882955 17721395025
Email
2423903095@qq.com
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China
ProdList
5000
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West fluorine technology co., ltd
Tel
0531-85906692 15588812394
Fax
86-0531-85906692
Email
325912682@qq.com
Country
China
ProdList
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SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
397
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jinanzhonglanhuagongyouxiangongsi
Tel
15169176553; 15169176553
Email
644658103@qq.com
Country
China
ProdList
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Jinan Fuzhe New Material Co., Ltd.
Tel
00-15169181 15169181281
Email
15169181281@163.com
Country
China
ProdList
262
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58
Shanghai Huafutai Chemical Co., Ltd
Tel
18662433356
Email
13906215003@163.com
Country
China
ProdList
295
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
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69
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View Lastest Price from Ethyl difluoroacetate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Ethyl difluoroacetate 454-31-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-05
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Ethyl difluoroacetate 454-31-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-13
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl difluoroacetate 454-31-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08

454-31-9, Ethyl difluoroacetateRelated Search:


  • DIFLUOROACETIC ACID ETHYL ESTER
  • ETHYL DIFLUOROACETATE
  • ETHYL DIFLUOROACETIC ACID
  • ART-CHEM-BB B020251
  • AKOS B020251
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  • ETHYL DIFLUOROACETATE 97%
  • Ethyldifluoroacetate,98%
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  • Difluoroacetic acid ethyl ester, Ethyl 2,2-difluoroethanoate
  • Ethyldifluorocetate
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  • Ethyl difluoroacetate(DFAE)
  • 454-31-9
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  • CHF2COOCH2CH3
  • F2CHCO2CH2CH3
  • F2CHCO2C2H5
  • F2CHOOCH2CH3
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