ChemicalBook > CAS DataBase List > 6-FLUORONICOTINIC ACID METHYL ESTER

6-FLUORONICOTINIC ACID METHYL ESTER

Product Name
6-FLUORONICOTINIC ACID METHYL ESTER
CAS No.
1427-06-1
Chemical Name
6-FLUORONICOTINIC ACID METHYL ESTER
Synonyms
uoropyridine-3-carboxyL;METHYL6-FLUORONICOTINATE;Methyl6-Fluoronicotinate>6-fluoro-3-Pyridinecarboxyli;Methyl 6-fluoronicotinate 98%;6-FLUORONICOTINIC ACID METHYL ESTER;6-Fluoro-3-(Methoxycarbonyl)pyridine;Methyl 6-fluoropyridin-3-carboxylate;methyl 6-fluoro-3-pyridinecarboxylate;Methyl 6-fluoropyridine-3-carboxylate
CBNumber
CB2241511
Molecular Formula
C7H6FNO2
Formula Weight
155.13
MOL File
1427-06-1.mol
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6-FLUORONICOTINIC ACID METHYL ESTER Property

Melting point:
48-52 °C
Boiling point:
210.3±20.0 °C(Predicted)
Density 
1.243±0.06 g/cm3(Predicted)
Flash point:
99 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
-2.47±0.10(Predicted)
form 
Solid
color 
White to Light yellow
InChI
InChI=1S/C7H6FNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3
InChIKey
HLYBWNNPVXFCPZ-UHFFFAOYSA-N
SMILES
C1=NC(F)=CC=C1C(OC)=O
CAS DataBase Reference
1427-06-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-36/37/39-45
WGK Germany 
3
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
697850
Product name
Methyl 6-fluoropyridine-3-carboxylate
Purity
97%
Packaging
250mg
Price
$87.7
Updated
2023/01/07
TCI Chemical
Product number
M2724
Product name
Methyl 6-Fluoronicotinate
Purity
>98.0%(GC)
Packaging
1g
Price
$82
Updated
2025/07/31
TCI Chemical
Product number
M2724
Product name
Methyl 6-Fluoronicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$271
Updated
2025/07/31
TRC
Product number
F593698
Product name
6-Fluoronicotinicacidmethylester
Packaging
250mg
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
PC49205
Product name
Methyl 6-Fluoronicotinate
Purity
98%
Packaging
25g
Price
$358
Updated
2021/12/16
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6-FLUORONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

403-45-2

18107-18-1

1427-06-1

General procedure for the synthesis of methyl 6-fluoronicotinate: 6-fluoronicotinate (255 mg, 1.32 mmol) was dissolved in methanol (5 mL) at room temperature, followed by the addition of (trimethylmethylsilyl) diazomethane (4.0 mL, 2 M of ether solution, 8.0 mmol). The reaction mixture was stirred at room temperature for 30 min and then concentrated. The resulting methyl 6-fluoronicotinate (129 mg, 47% yield) was used without further purification. Its nuclear magnetic resonance hydrogen spectrum (1H NMR, 600 MHz, DMSO-d6) data were as follows: δ 8.79 (d, J=2.6 Hz, 1H), 8.47 (td, J=7.9,2.6 Hz, 1H), 7.35 (ddd, J=8.5,2.6,0.6 Hz, 1H), 3.88 (s, 3H). The calculated value for electrospray ionization mass spectrometry (ESIMS) was 156.0 (M++H) and the measured value was 156.1 (M++H).

References

[1] Patent: WO2007/2248, 2007, A2. Location in patent: Page/Page column 76

6-FLUORONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-FLUORONICOTINIC ACID METHYL ESTER Suppliers

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View Lastest Price from 6-FLUORONICOTINIC ACID METHYL ESTER manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-30
Henan Fengda Chemical Co., Ltd
Product
6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Career Henan Chemical Co
Product
6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100KGS
Release date
2018-12-14

1427-06-1, 6-FLUORONICOTINIC ACID METHYL ESTERRelated Search:

Ethyl 6-bromopicolinate Methyl nicotinate 2-FLUORONICOTINIC ACID METHYL ESTER 2-Fluoropyridine-5-carboxaldehyde 6-Fluoronicotinic acid METHYL 2,6-DIFLUORONICOTINATE 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE 2-Fluoro-5-methylpyridine 6-FLUORONICOTINIC ACID METHYL ESTER

  • 6-FLUORONICOTINIC ACID METHYL ESTER
  • METHYL6-FLUORONICOTINATE
  • Methyl 6-fluoronicotinate 98%
  • methyl 6-fluoro-3-pyridinecarboxylate
  • Methyl 6-fluoropyridine-3-carboxylate
  • 3-Pyridinecarboxylic acid, 6-fluoro-, methyl ester
  • Methyl 6-fluoropyridine-3-carboxylate, 6-Fluoro-3-(methoxycarbonyl)pyridine
  • 6-fluoro-3-Pyridinecarboxylic acid Methyl ester
  • 6-Fluoro-3-(Methoxycarbonyl)pyridine
  • 6-fluoro-3-Pyridinecarboxyli
  • Methyl6-Fluoronicotinate&gt
  • uoropyridine-3-carboxyL
  • 6-Fluoropyridine-3-carboxylic Acid Methyl Ester
  • 6-FLUORONICOTINIC ACID METHYL ESTER ISO 9001：2015 REACH
  • 3-Pyridinecarboxylic acid, 6-fluoro-, methyl ester (9CI, ACI)
  • 6-fluoro-3-Pyridinecarboxylic acid methyl ester (9CI ACI)
  • 6-Fluoropyridin-3-carboxylic acid methyl ester
  • Methyl 6-fluoropyridin-3-carboxylate
  • 1427-06-1
  • C6H3FNO2
  • Imidazoles ,Homopiperidines
  • Fluorine series
  • Picolinic acid series
  • Pyridines
  • Boronic Acid
  • Pyridine
  • pharmacetical