2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE

Product Name: 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
CAS No.: 131747-55-2
Chemical Name: 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
Synonyms: 2-Fluoro-3-pyridinemethanol;2-Fluoro-3-pyridinecarbinol;3-Pyridinemethanol, 2-fluoro-;(2-Fluoropyridin-3-yl)methanol;3-Pyridinemethanol,2-fluoro-(9CI);2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
CBNumber: CB2375153
Molecular Formula: C6H6FNO
Formula Weight: 127.12
MOL File: 131747-55-2.mol

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2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Property

Boiling point:: 249℃
Density: 1.262
Flash point:: 105℃
storage temp.: Inert atmosphere,2-8°C
pka: 12.94±0.10(Predicted)
Appearance: Colorless to light yellow Liquid
CAS DataBase Reference: 131747-55-2(CAS DataBase Reference)

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Frontier Specialty Chemicals

Product number: F12928
Product name: 2-(Fluoro-3-pyridine)methanol
Purity: 97%
Packaging: 1g
Price: $17
Updated: 2021/12/16

AK Scientific

Product number: J50839
Product name: 2-Fluoro-3-(hydroxymethyl)pyridine
Packaging: 1g
Price: $30
Updated: 2021/12/16

ChemScene

Product number: CS-D0977
Product name: 2-Fluoro-3-(hydroxymethyl)pyridine
Purity: 99.90%
Packaging: 5g
Price: $50
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: F12928
Product name: 2-(Fluoro-3-pyridine)methanol
Purity: 97%
Packaging: 5g
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-3-19
Product name: 2-Fluoro-3-(Hydroxymethyl)pyridine
Purity: 95%
Packaging: 1g
Price: $70
Updated: 2021/12/16

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2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Chemical Properties,Usage,Production

Synthesis

36404-90-7

131747-55-2

General procedure for the synthesis of 2-fluoro-3-hydroxymethylpyridine using 2-fluoro-3-pyridinecarboxaldehyde as starting material: sodium borohydride (1.0 g, 26 mmol) was slowly added to a solution of 2-fluoro-3-pyridinecarboxaldehyde (1.6 mL, 16 mmol) in ethanol (14 mL), and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, water was added to the reaction mixture, followed by extraction with ethyl acetate. The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure to afford the target product 2-fluoro-3-hydroxymethylpyridine (1.3 g, 10 mmol, 63% yield) as a colorless oil.

References

[1] Patent: EP3333163, 2018, A1. Location in patent: Paragraph 1401; 1402
[2] Patent: WO2010/132999, 2010, A1. Location in patent: Page/Page column 98
[3] Patent: WO2011/48082, 2011, A1. Location in patent: Page/Page column 88
[4] Organic Letters, 2017, vol. 19, # 14, p. 3895 - 3898

2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Suppliers

China 93 Europe 1 Germany 1 India 1 United Kingdom 3 United States 14 Global 113

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View Lastest Price from 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE manufacturers

Honest Joy Holdings Limited

Product: 2-Fluoro-3-(hydroxymethyl)pyridine 131747-55-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.3%
Supply Ability: 100 tons
Release date: 2022-01-25

Career Henan Chemical Co

Product: 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE 131747-55-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

131747-55-2, 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINERelated Search:

6-FLUORO-2-METHYLNICOTINIC ACID 2-FLUORO-4-IODONICOTINIC ACID 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 5-chloro-2-fluoro-3-Pyridinemethanol 2,6-Difluoropyridine-3-carboxylic acid 4,6-Difluoronicotinic acid 6-Fluoronicotinic acid 5-CHLORO-2-FLUORONICOTINIC ACID 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE 2-Fluoronicotinic acid 2-FLUORONICOTINIC ACID METHYL ESTER 2-FLUORO-3-METHYL-PYRIDINE-5-CARBOXYLIC ACID 6-FLUORONICOTINIC ACID METHYL ESTER 6-Chloro-3-fluoro-2-(hydroxymethyl)pyridine 2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE,6-Fluoro-3-(Hydroxymethyl)Pyridine 2-CHLORO-5-FLUORO-4-(HYDROXYMETHYL)PYRIDINE 2-CHLORO-5-FLUORO-3-(HYDROXYMETHYL)PYRIDINE 3-Pyridinemethanol

2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE

3-Pyridinemethanol,2-fluoro-(9CI)

2-Fluoro-3-pyridinecarbinol

2-Fluoro-3-pyridinemethanol

(2-Fluoropyridin-3-yl)methanol

3-Pyridinemethanol, 2-fluoro-

131747-55-2

PYRIDINE

Pyridines