2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
- Product Name
- 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
- CAS No.
- 131747-55-2
- Chemical Name
- 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
- Synonyms
- 2-Fluoro-3-pyridinemethanol;2-Fluoro-3-pyridinecarbinol;3-Pyridinemethanol, 2-fluoro-;(2-Fluoropyridin-3-yl)methanol;3-Pyridinemethanol,2-fluoro-(9CI);2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE
- CBNumber
- CB2375153
- Molecular Formula
- C6H6FNO
- Formula Weight
- 127.12
- MOL File
- 131747-55-2.mol
2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Property
- Boiling point:
- 249℃
- Density
- 1.262
- Flash point:
- 105℃
- storage temp.
- Inert atmosphere,2-8°C
- pka
- 12.94±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
- CAS DataBase Reference
- 131747-55-2(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F12928
- Product name
- 2-(Fluoro-3-pyridine)methanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $17
- Updated
- 2021/12/16
- Product number
- J50839
- Product name
- 2-Fluoro-3-(hydroxymethyl)pyridine
- Packaging
- 1g
- Price
- $30
- Updated
- 2021/12/16
- Product number
- CS-D0977
- Product name
- 2-Fluoro-3-(hydroxymethyl)pyridine
- Purity
- 99.90%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- F12928
- Product name
- 2-(Fluoro-3-pyridine)methanol
- Purity
- 97%
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4H01-3-19
- Product name
- 2-Fluoro-3-(Hydroxymethyl)pyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Chemical Properties,Usage,Production
Synthesis
36404-90-7
131747-55-2
General procedure for the synthesis of 2-fluoro-3-hydroxymethylpyridine using 2-fluoro-3-pyridinecarboxaldehyde as starting material: sodium borohydride (1.0 g, 26 mmol) was slowly added to a solution of 2-fluoro-3-pyridinecarboxaldehyde (1.6 mL, 16 mmol) in ethanol (14 mL), and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, water was added to the reaction mixture, followed by extraction with ethyl acetate. The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure to afford the target product 2-fluoro-3-hydroxymethylpyridine (1.3 g, 10 mmol, 63% yield) as a colorless oil.
References
[1] Patent: EP3333163, 2018, A1. Location in patent: Paragraph 1401; 1402
[2] Patent: WO2010/132999, 2010, A1. Location in patent: Page/Page column 98
[3] Patent: WO2011/48082, 2011, A1. Location in patent: Page/Page column 88
[4] Organic Letters, 2017, vol. 19, # 14, p. 3895 - 3898
2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE Suppliers
- Tel
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- sales@chemos-group.com
- Country
- Germany
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View Lastest Price from 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE manufacturers
- Product
- 2-Fluoro-3-(hydroxymethyl)pyridine 131747-55-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.3%
- Supply Ability
- 100 tons
- Release date
- 2022-01-25
- Product
- 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE 131747-55-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25