2-(7-Methoxynaphthalen-1-yl)acetic acid

Product Name: 2-(7-Methoxynaphthalen-1-yl)acetic acid
CAS No.: 6836-22-2
Chemical Name: 2-(7-Methoxynaphthalen-1-yl)acetic acid
Synonyms: 7-Methyl-1-naphthyl acetic acid;(7-Methoxy-1-naphthyl)acetic acid;7-Methoxy-1-napthalene acetic acid;7-Methoxy-1-naphthaleneacetic acid;2-(7-Methoxy-1-naphthyl)acetic Acid;1-Naphthaleneacetic acid, 7-Methoxy-;2-(7-Methoxynaphthalen-1-yl)AceticAci;2-(7-Methoxyphthalen-1-yl)acetic acid;2-(7-Methoxynaphthalen-1-yl)acetic acid;7-Methoxy-1-naphthaleneacetic acid, 10 mM in DMSO
CBNumber: CB22462143
Molecular Formula: C13H12O3
Formula Weight: 216.23
MOL File: 6836-22-2.mol

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2-(7-Methoxynaphthalen-1-yl)acetic acid Property

Melting point:: 153-154 ºC
Boiling point:: 408.8±20.0 °C(Predicted)
Density: 1.235
storage temp.: Sealed in dry,Room Temperature
solubility: Dichloromethane (Slightly), Methanol (Slightly)
form: Solid
pka: 4.33±0.30(Predicted)
color: White to Off-White

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2888
Product name: 7-Methoxy-1-naphthaleneacetic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $93
Updated: 2025/07/31

TCI Chemical

Product number: M2888
Product name: 7-Methoxy-1-naphthaleneacetic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $279
Updated: 2025/07/31

TRC

Product number: M265788
Product name: 2-(7-Methoxynaphthalen-1-yl)aceticAcid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: B669
Product name: 7-Methoxy-1-naphthaleneacetic Acid
Packaging: 5g
Price: $61
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2621-1-61
Product name: 2-(7-Methoxynaphthalen-1-yl)acetic acid
Packaging: 1g
Price: $232
Updated: 2021/12/16

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2-(7-Methoxynaphthalen-1-yl)acetic acid Chemical Properties,Usage,Production

Uses

7-Methyl-1-naphthyl acetic acid is a potent inhibitor of auxin action in plants. 7-Methyl-1-naphthyl acetic acid inhibits AUX1, PIN, and ABCB protein-mediated auxin transport expressed in yeast. 7-Methyl-1-naphthyl acetic acid can be used in auxin dependent development [1].

Synthesis

6836-21-1

6836-22-2

Step 3 Synthesis of (7-methoxy-1-naphthyl)acetic acid: To a solution of methanol (12 mL) containing ethyl 7-methoxy-1-naphthylacetate (2.38 g, 9.8 mmol), sodium hydroxide (0.62 g, 15.6 mmol) and water (6 mL) were added. The reaction mixture was heated at 40°C for about 2 hours with continuous stirring. Upon completion of the reaction, the mixture was concentrated under reduced pressure and the residue was diluted with 50 mL of water and extracted with ether (4 x 25 mL). The aqueous phase was acidified with concentrated hydrochloric acid to pH=2. After conventional extraction and post-treatment, the title compound 7-methoxy-1-naphthaleneacetic acid was obtained as an off-white solid (1.9 g, 90% yield). The product was confirmed by 1H NMR (300 MHz, CD3OD): δ 3.9 (s, 3H), 4.03 (s, 2H), 7.15 (dd, J = 9.0, 2.4 Hz, 1H), 7.27-7.41 (m, 4H), 7.76 (m, 2H); LC-MS showed the molecular ion peak as 215 (M + H)+.

References

[1] Tsuda E, et al. Alkoxy-auxins are selective inhibitors of auxin transport mediated by PIN, ABCB, and AUX1 transporters. J Biol Chem. 2011 Jan 21;286(3):2354-64. DOI:10.1074/jbc.M110.171165

2-(7-Methoxynaphthalen-1-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(7-Methoxynaphthalen-1-yl)acetic acid Suppliers

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View Lastest Price from 2-(7-Methoxynaphthalen-1-yl)acetic acid manufacturers

Career Henan Chemical Co

Product: 2-(7-Methoxynaphthalen-1-yl)acetic acid 6836-22-2
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-09

6836-22-2, 2-(7-Methoxynaphthalen-1-yl)acetic acidRelated Search:

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6836-22-2

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