2'-deoxy-2'-fluoro-2'-C-methylcytidine
- Product Name
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine
- CAS No.
- 817204-33-4
- Chemical Name
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine
- Synonyms
- ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130(R 1656);PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine
- CBNumber
- CB22525888
- Molecular Formula
- C10H14FN3O4
- Formula Weight
- 259.23
- MOL File
- 817204-33-4.mol
2'-deoxy-2'-fluoro-2'-C-methylcytidine Property
- Melting point:
- 216-218℃
- Boiling point:
- 482.4±55.0 °C(Predicted)
- Density
- 1.67
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Methanol (Slightly), Water (Slightly)
- pka
- 12.86±0.70(Predicted)
- form
- Solid
- color
- White to Light Brown
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 13575
- Product name
- PSI-6130
- Packaging
- 1mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 13575
- Product name
- PSI-6130
- Packaging
- 5mg
- Price
- $321
- Updated
- 2024/03/01
- Product number
- P839680
- Product name
- PSI6130
- Packaging
- 25mg
- Price
- $640
- Updated
- 2021/12/16
- Product number
- 097930
- Product name
- 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $685
- Updated
- 2021/12/16
- Product number
- orb146167
- Product name
- PSI6130
- Purity
- >99%
- Packaging
- 1g
- Price
- $765
- Updated
- 2021/12/16
2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemical Properties,Usage,Production
Description
PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).
Uses
PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.
target
Hepatitis C Virus Nucleoside
2'-deoxy-2'-fluoro-2'-C-methylcytidine Preparation Products And Raw materials
Raw materials
Preparation Products
2'-deoxy-2'-fluoro-2'-C-methylcytidine Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
View Lastest Price from 2'-deoxy-2'-fluoro-2'-C-methylcytidine manufacturers
- Product
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-22
- Product
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-08-05