Tylvalosin tartrate
- Product Name
- Tylvalosin tartrate
- CAS No.
- 63428-13-7
- Chemical Name
- Tylvalosin tartrate
- Synonyms
- Tylvalosin Tartrate;Acetylisovaleryltylosin Tartrate;Acetylisovaleryltylosin Tartrat;Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt);Aivlosin Tartrate;Tawanthin tartrate;TYLVALOSIN TARTRATE PREMIX;Acetylisovalerylosin tartrate;Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate;TIANFU-CHEM Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7
- CBNumber
- CB22534581
- Molecular Formula
- C57H93NO25
- Formula Weight
- 1192.35
- MOL File
- 63428-13-7.mol
Tylvalosin tartrate Property
- Melting point:
- 208 - 211°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- InChIKey
- OLLSDNUHBJHKJS-YZBHKUDENA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0099515
- Product name
- Tylvalosintartrate
- Packaging
- 25mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 097240
- Product name
- Acetylisovaleryltylosin tartrate
- Purity
- 80%
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 9668AB
- Product name
- Acetylisovaleryltylosintartrate
- Packaging
- 1g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- API0019489
- Product name
- ACETYLISOVALERYLTYLOSIN TARTRATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $284.55
- Updated
- 2021/12/16
- Product number
- J50036
- Product name
- Acetylisovaleryltylosintartrate,tech.
- Packaging
- 5g
- Price
- $298
- Updated
- 2021/12/16
Tylvalosin tartrate Chemical Properties,Usage,Production
Uses
Tylvalosin Tartrate is an impurity of Tylvalosin (T898210); Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.
Pharmacokinetics
Tylvalosin tartrate is a macrolide antibiotic with antibacterial activity against Gram-positive and some Gram-negative organisms and mycoplasma. It acts by inhibiting protein synthesis in the bacterial cell. Macrolide antibiotics are metabolites or semi-synthetic derivatives of metabolites of soil organisms obtained by fermentation. They have differently-sized lactone rings and are essential due to the dimethylamino group. Tylvalosin has a sixteen-membered ring. Macrolides interfere with protein synthesis by reversibly binding to the 50S ribosome subunit.
Pharmacology
Tylvalosin tartrate is rapidly absorbed after oral administration of Aivlosin. After administration of the recommended dose, lung concentrations of 0.060–0.066 μg/ml were found at 2 and 12 hours post-treatment. The parent compound is widely distributed in the tissues, with the highest concentrations found in the lungs, bile, intestinal mucosa, spleen, kidney, and liver. There is evidence that the concentration of macrolides is higher at the site of infection than in plasma, particularly in neutrophils, alveolar macrophages, and alveolar epithelial cells. In vitro metabolism studies have confirmed that the parent compound is rapidly metabolised to 3-O-acetyltylosin. In a trial with 14C-labeled Aivlosin administered at 2.125 mg/kg to pigs for 7 days, over 70% of the dose was excreted in the feces, with urinary excretion accounting for 3 to 4% of the dose.
in vitro
Tylvalosin tartrate (10 μg/mL; 0.5, 1 h) increases caspase-3 cleavage in porcine neutrophils, leading to DNA fragmentation during apoptosis.Tylvalosin tartrate (0.1-10 μg/mL; 0.5 h) Promote endocytosis of porcine neutrophils by macrophages without changing phagocytosis.
Tylvalosin tartrate Preparation Products And Raw materials
Raw materials
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View Lastest Price from Tylvalosin tartrate manufacturers
- Product
- Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- 10tons
- Release date
- 2024-04-24
- Product
- Acetylisovaleryltylosin Tartrate 63428-13-7
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-01
- Product
- Tylvalosin tartrate 63428-13-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 80% 90%
- Supply Ability
- 20tons
- Release date
- 2023-09-20