4-Chloro-3-nitrotoluene

Product Name: 4-Chloro-3-nitrotoluene
CAS No.: 89-60-1
Chemical Name: 4-Chloro-3-nitrotoluene
Synonyms: 4-Chloro-3-nit;4,3-Chloronitrotoluene;3-nitro-4-chlorotoluol;4-CHLORO-3-NITROTOLUENE;M-NITRO-P-CHLOROTOLUENE;3-NITRO-4-CHLORO TOLUENE;toluene,4-chloro-3-nitro-;Toluene, 4-chloro-3-nitro-;4-Chloro-3-nitrotoluene,99%;4-Chloro-3-nitrotoluene 97%
CBNumber: CB2259222
Molecular Formula: C7H6ClNO2
Formula Weight: 171.58
MOL File: 89-60-1.mol

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4-Chloro-3-nitrotoluene Property

Melting point:: 7 °C(lit.)
Boiling point:: 260 °C745 mm Hg(lit.)
Density: 1.297 g/mL at 25 °C(lit.)
refractive index: n20/D 1.558(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
form: clear liquid
color: Light yellow to Yellow to Orange
BRN: 511055
InChIKey: NWESJZZPAJGHRZ-UHFFFAOYSA-N
CAS DataBase Reference: 89-60-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1-chloro-4-methyl-2-nitro-(89-60-1)
EPA Substance Registry System: Benzene, 1-chloro-4-methyl-2-nitro- (89-60-1)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-36/37/38-20/21/22-52/53-51/53-36/38-33
Safety Statements: 36/37/39-26-61-57-36/37-23-9
RIDADR: UN 2433 6.1/PG 3
WGK Germany: 3
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29049085

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 213055
Product name: 4-Chloro-3-nitrotoluene
Purity: technical grade
Packaging: 100g
Price: $165
Updated: 2025/07/31

TCI Chemical

Product number: C0232
Product name: 4-Chloro-3-nitrotoluene
Purity: >97.0%(GC)
Packaging: 25g
Price: $45
Updated: 2025/07/31

TRC

Product number: C374820
Product name: 4-Chloro-3-nitrotoluene
Packaging: 5g
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: U032
Product name: 4-Chloro-3-nitrotoluene
Packaging: 25g
Price: $27
Updated: 2021/12/16

AK Scientific

Product number: J95615
Product name: 4-Chloro-3-nitrotoluene
Packaging: 100g
Price: $49
Updated: 2021/12/16

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4-Chloro-3-nitrotoluene Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

4-Chloro-3-nitrotoluene is used in the synthesis of quinazoline-2,4(1H,3H)-dione derivatives as PARP-2 selective inhibitors.

Uses

4-Chloro-3-nitrotoluene was used in the synthesis of 4-(2-hydroxyethylamino)-3-nitrotoluene.

Synthesis Reference(s)

The Journal of Organic Chemistry, 42, p. 2426, 1977 DOI: 10.1021/jo00434a017

General Description

Vibrational spectral analysis of 4-chloro-3-nitrotoluene has been studied using Raman and IR spectroscopy.

Synthesis

27329-27-7

89-60-1

General procedure for the synthesis of 1-chloro-4-methyl-2-nitrobenzene from 4-methyl-2-nitrobenzoic acid: 6.2 mg of silver sulfate, 36.3 mg of copper acetate, 12.5 mg of 2,9-dimethyl-1,10-o-phenanthroline, 36.2 mg of 4-methyl-2-nitrobenzoic acid, and 17.5 mg of sodium chloride were added sequentially to a Silak reactor tube fitted with a magnetic stirrer. NaCl, followed by the addition of 4 mL of dimethyl sulfoxide as solvent. The reaction mixture was heated and stirred at 160 °C for 24 hours under an oxygen atmosphere. Upon completion of the reaction, the reaction was quenched by the addition of appropriate amount of distilled water and extracted three times with ethyl acetate (10 mL each time). The organic phases were combined and concentrated under reduced pressure to give 17.5 mg of 1-chloro-4-methyl-2-nitrobenzene in 51% yield.

References

[1] Patent: CN107325002, 2017, A. Location in patent: Paragraph 0091
[2] Organic and Biomolecular Chemistry, 2018, vol. 16, # 30, p. 5416 - 5421
[3] Journal of Organic Chemistry, 2016, vol. 81, # 7, p. 2794 - 2803

4-Chloro-3-nitrotoluene Preparation Products And Raw materials

Raw materials

Copper(I) chloride 3-Nitrotoluene

Preparation Products

2-Amino-4-methylbenzonitrile 2-Methoxy-5-methylaniline Meclofenamic acid

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4-Chloro-3-nitrotoluene Suppliers

Americas 1 Belgium 3 China 150 Europe 1 France 1 Germany 9 India 4 Japan 2 Poland 1 Switzerland 2 United Kingdom 11 United States 38 Global 223

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View Lastest Price from 4-Chloro-3-nitrotoluene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Chloro-3-nitrotoluene 89-60-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Henan Fengda Chemical Co., Ltd

Product: 4-Chloro-3-nitrotoluene 89-60-1
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-24

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Chloro-3-nitrotoluene 89-60-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2020-01-07

89-60-1, 4-Chloro-3-nitrotolueneRelated Search:

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89-60-1

Nitrogen Compounds

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Nitro Compounds

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Aromatic Hydrocarbons (substituted) & Derivatives

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Nitro Compounds

Nitrogen Compounds

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Nitro Compounds

Nitrogen Compounds

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