4-Chloro-3,5-dinitrobenzoic acid
- Product Name
- 4-Chloro-3,5-dinitrobenzoic acid
- CAS No.
- 118-97-8
- Chemical Name
- 4-Chloro-3,5-dinitrobenzoic acid
- Synonyms
- 4-Chloro-3;AKOS 212-81;4-C-3,5-DNBA;CBI-BB ZERO/005300;TIMTEC-BB SBB003176;RARECHEM AL BO 0221;LABOTEST-BB LT00117948;4-chloro-3,5-dinitrobenzoate;4-chloro-3,5-dinitro-benzoicaci;4-CHLORO-3,5-DINITROBENZOIC ACID
- CBNumber
- CB6753319
- Molecular Formula
- C7H3ClN2O6
- Formula Weight
- 246.56
- MOL File
- 118-97-8.mol
4-Chloro-3,5-dinitrobenzoic acid Property
- Melting point:
- 159-162 °C (lit.)
- Boiling point:
- 315°C
- Density
- 1.9543 (rough estimate)
- refractive index
- 1.6500 (estimate)
- Flash point:
- 186°C
- storage temp.
- Sealed in dry,2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 2?+-.0.10(Predicted)
- color
- Light orange to Yellow to Green
- BRN
- 668253
- InChI
- InChI=1S/C7H3ClN2O6/c8-6-4(9(13)14)1-3(7(11)12)2-5(6)10(15)16/h1-2H,(H,11,12)
- InChIKey
- PCTFIHOVQYYAMH-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC([N+]([O-])=O)=C(Cl)C([N+]([O-])=O)=C1
- CAS DataBase Reference
- 118-97-8(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 4-chloro-3,5-dinitro- (118-97-8)
Safety
- Hazard Codes
- Xi,E
- Risk Statements
- 38-36/37/38-36/38-2
- Safety Statements
- 28-24/25-22-35-26
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- C38907
- Product name
- 4-Chloro-3,5-dinitrobenzoic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $65
- Updated
- 2023/06/20
- Product number
- C38907
- Product name
- 4-Chloro-3,5-dinitrobenzoic acid
- Purity
- 97%
- Packaging
- 100g
- Price
- $210
- Updated
- 2023/06/20
- Product number
- C0607
- Product name
- 4-Chloro-3,5-dinitrobenzoic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $74
- Updated
- 2024/03/01
- Product number
- C0607
- Product name
- 4-Chloro-3,5-dinitrobenzoic Acid
- Purity
- >98.0%(T)
- Packaging
- 250g
- Price
- $471
- Updated
- 2024/03/01
- Product number
- A12373
- Product name
- 4-Chloro-3,5-dinitrobenzoic acid, 99%
- Packaging
- 25g
- Price
- $50.65
- Updated
- 2024/03/01
4-Chloro-3,5-dinitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
yellow crystals
Uses
4-Chloro-3,5-dinitrobenzoic-15N2 Acid is an intermediate in synthesizing Lodoxamide-15N2,d2 (L469367), a labelled form of Lodoxamide. It is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
Hazard
irritant
Synthesis
The synthesis of 4-Chloro-3,5-dinitrobenzoic acid is as follows:
4-chloro-benzoic acid (20 g, 0.128 mol) was dissolved in H2SO4 (d = 1.835 g/mL, 300 mL) at80 C, and KNO3 (66 g, 0.65 mol) was added. The reaction mixture was heated to 125 C using ahigh-pressure flask and kept for 2 h, after which the reaction was cooled to rt and poured onto ice.The yield of 4-Chloro-3,5-dinitrobenzoic acid was 28 g (89%) .
Purification Methods
Crystallise the acid from EtOH/ H2O, EtOH or *C6H6. The 1:1 naphthalene complex (by fusing various ratios of ingredients and recrystallising from EtOH) has m 122o. [Beilstein 9 H 416, 9 III 1953, 9 IV 1360.]
4-Chloro-3,5-dinitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-3,5-dinitrobenzoic acid manufacturers
- Product
- 4-Chloro-3,5-dinitrobenzoic acid 118-97-8
- Price
- US $34.88/Kg/Drum
- Min. Order
- 25Kg/Drum
- Purity
- 99.00%HPLC
- Supply Ability
- 10tons/month
- Release date
- 2021-09-23
- Product
- 4-Chloro-3,5-dinitrobenzoic acid 118-97-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29
- Product
- 4-Chloro-3,5-dinitrobenzoic acid 118-97-8
- Price
- US $10.70/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-23