ChemicalBook > CAS DataBase List > Kinsenoside
Kinsenoside
- Product Name
- Kinsenoside
- CAS No.
- 151870-74-5
- Chemical Name
- Kinsenoside
- Synonyms
- Kinsenoside;(+)-Kinsenoside;(4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone;2(3H)-Furanone, 4-(β-D-glucopyranosyloxy)dihydro-, (4R)-;(4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one;(R)-4-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)dihydrofuran-2(3H)-one;Keap1-Nrf2,Inhibitor,pulposus,disc,degeneration,Kinsenoside,inhibit,cells,nucleus,Nrf2,Apoptosis,intervertebral
- CBNumber
- CB22645474
- Molecular Formula
- C10H16O8
- Formula Weight
- 264.23
- MOL File
- 151870-74-5.mol
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Kinsenoside Property
- Boiling point:
- 570.2±50.0 °C(Predicted)
- Density
- 1.59±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMF:14.0(Max Conc. mg/mL);52.98(Max Conc. mM)
DMSO:33.0(Max Conc. mg/mL);124.89(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);37.85(Max Conc. mM) - form
- A crystalline solid
- pka
- 12.81±0.70(Predicted)
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25144
- Product name
- Kinsenoside
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25144
- Product name
- Kinsenoside
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25144
- Product name
- Kinsenoside
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $341
- Updated
- 2024/03/01
TRC
- Product number
- K570200
- Product name
- Kinsenoside
- Packaging
- 10mg
- Price
- $420
- Updated
- 2021/12/16
Usbiological
- Product number
- 300531
- Product name
- Kinsenoside
- Packaging
- 25mg
- Price
- $907
- Updated
- 2021/12/16
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Kinsenoside Chemical Properties,Usage,Production
Description
Kinsenoside is a glycoside originally isolated from A. formosanus that has diverse biological activities, including antihyperlipidemic, immunosuppressive, and anti-inflammatory properties. It increases lipolysis mediated by adipose triglyceride lipase and increases hydrolysis of triglycerides in C3H10T1/2 adipocytes. It also increases phosphorylation of peroxisome proliferator-activated receptor α (PPARα) and CREB as well as protein levels of SIRT1, PGC-1α, and carnitine palmitoyltransferase I. Kinsenoside downregulates the expression and phosphorylation of VEGF receptor 2 (VEGFR2) and inhibits crosstalk between the JAK2/STAT3 and PI3K/AKT signaling pathways in dendritic cells in vitro. It decreases the production of IFN-γ, IL-17, and TNF-α and increases the production of IL-10 in splenocytes isolated from mice with collagen-induced arthritis (CIA). Kinsenoside (300 mg/kg per day) decreases the expression of IL-1β, TNF-α, and matrix metalloproteinase-9 (MMP-9) and increases the expression of IL-10 in inflamed joints in a mouse model of collagen-induced arthritis and prevents paw edema and reduces the severity of arthritis.
Uses
Kinsenoside is an anti-hyperlipidemic agent isolated from the plant Anoect chilus.
Definition
ChEBI: (3R)-5-Oxotetrahydro-3-furanyl beta-D-glucopyranoside is a glycoside.
Kinsenoside Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Kinsenoside manufacturers
Shanghai Standard Technology Co., Ltd.
- Product
- Kinsenoside 151870-74-5
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-24
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